Results 11 to 20 of about 98,046 (284)
Aldehydes: magnificent acyl equivalents for direct acylation [PDF]
Organic & Biomolecular Chemistry, 2020 This review sheds light on the use of aldehydes in the selective acylation of arene, heteroarene and alkyl (sp3, sp2and sp) C–H bonds by proficient utilization of the C–H activation strategy.
Vijay Bahadur +9 more
openaire +4 more sources
Detection of S-Acylated CD95 by Acyl-Biotin Exchange [PDF]
, 2017 S-acylation is the covalent addition of a fatty acid, most generally palmitate onto cysteine residues of proteins through a labile thioester linkage. The death receptor CD95 is S-palmitoylated and this post-translational modification plays a crucial role on CD95 organization in cellular membranes and thus on CD95-mediated signaling.
Rossin, Aurélie, Hueber, Anne-Odile
openaire +3 more sources
The Arabidopsis Book, 2010 Acyl lipids in Arabidopsis and all other plants have a myriad of diverse functions. These include providing the core diffusion barrier of the membranes that separates cells and subcellular organelles. This function alone involves more than 10 membrane lipid classes, including the phospholipids, galactolipids, and sphingolipids, and within each class ...
Katherine M. Schmid +27 more
openaire +7 more sources
Acylation of glycerolipids in mycobacteria
Nature Communications, 2023 AbstractWe report on the existence of two phosphatidic acid biosynthetic pathways in mycobacteria, a classical one wherein the acylation of the sn-1 position of glycerol-3-phosphate (G3P) precedes that of sn-2 and another wherein acylations proceed in the reverse order.
Shiva Kumar Angala +15 more
openaire +4 more sources
Versatility of Acyl-Acyl Carrier Protein Synthetases
Chemistry & Biology, 2014 The acyl carrier protein (ACP) requires posttranslational modification with a 4'-phosphopantetheine arm for activity, and this thiol-terminated modification carries cargo between enzymes in ACP-dependent metabolic pathways. We show that acyl-ACP synthetases (AasSs) from different organisms are able to load even, odd, and unnatural fatty acids onto E ...
Kara Finzel +2 more
openaire +3 more sources
An engineered Tetrahymena tRNA(Gln) for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression [PDF]
, 1996 A new tRNA, THG73, has been designed and evaluated as a vehicle for incorporating unnatural amino acids site-specifically into proteins expressed in vivo using the stop codon suppression technique.
Abelson, John N. +7 more
core +1 more source
A Receptor Component of the Chloroplast Protein Translocation Machinery [PDF]
, 1994 The chloroplast outer envelope protein OEP86 functions as a receptor in precursor protein translocation into chloroplasts. Sequence analysis suggests that the precursor of OEP86 is directed to the chloroplast outer envelope by a cleavable, negatively ...
Heemeyer, Frank +4 more
core +1 more source
A broad inhibitor of acyl-acyl carrier protein synthetases
Biochemistry and Biophysics Reports, 2023 The acyl-acyl carrier protein synthetase enzyme enables some bacteria to scavenge free fatty acids from the environment for direct use in lipids. This fatty acid recycling pathway can help pathogens circumvent fatty acid synthase (FAS) inhibition with established antibiotics and those in clinical development.
Magdalena Todorinova +2 more
openaire +3 more sources
Acylated and non-acylated anthocyanins as antibacterial and antibiofilm agents
Discover Food, 2023 AbstractNatural products have served as an essential source of medicinal compounds in drug discovery, with their high abundance in nature and structural complexity being beneficial for various biological activities. Anthocyanins are a natural food colourant that belongs to the flavonoid group of compounds responsible for the colour of various fruits ...
Jeyaraj, Ethel Jeyaseela +3 more
openaire +4 more sources
Correction: de Gonzalo, G. Lipase Catalysed Kinetic Resolution of Racemic 1,2-Diols Containing a Chiral Quaternary Center. Molecules 2018, 23, 1585 [PDF]
, 2018 n/
Gonzalo Calvo, Gonzalo de
core +1 more source