Results 191 to 200 of about 89,225 (346)

S-acylation and membrane localization of the small GTPase ARL15 are mediated by the Golgi S-acyltransferases ZDHHC7 and ZDHHC3. [PDF]

J Biol Chem
Chino T, Araki M, Ashi Y, Izawa Y, Nunami Y, Ichikawa Y, Kuroiwa I, Kontani K.   +7 more
europepmc   +1 more source

High‐Resolution LC–MS/MS Characterization of Budmunchiamine‐Type Alkaloids in Albizia niopoides

Rapid Communications in Mass Spectrometry, Volume 40, Issue 19, 15 October 2026.
ABSTRACT Rationale Budmunchiamines are macrocyclic spermine alkaloids that constitute a distinctive class of polyamine natural products predominantly found in species of the genus Albizia. Comprehensive characterization of these compounds remains challenging because of their structural diversity and the limited availability of reference standards. This
Maria L. A. Majevski, Lienne D'Auria Lima, Adriana C. C. Reis, Leonan I. C. R. Santos, Brenno F. S. Vargas, Markus Kohlhoff, Geraldo Célio Brandão   +6 more
wiley   +1 more source

Reversible one-step acylation facilitates mitochondrial delivery of functional RNA. [PDF]

Chem Sci
Zhuang Y, Liu X, Shen Y, Wang Q, Lin Z, Zeng Q, Chen X, Jiang L, Yao SQ, Ge J.   +9 more
europepmc   +1 more source

Controllable Chemodivergent Synthesis of α‐Trifluoromethyl Boronates and gem‐Difluoroalkenyl Boronates via Photoredox 1,2‐Boron Migratory Carbonylation

Chinese Journal of Chemistry, Volume 44, Issue 17, Page 2918-2926, 1 September 2026.
We have developed a visible‐light‐driven, transition‐metal‐free protocol for the chemodivergent borocarbonylation of trifluoromethyl styrenes which integrates radical 1,2‐boron migration, CO trapping, and intermolecular C–C bond formation into a single multicomponent cascade.
Xiao‐Fan Cui, Le‐Cheng Wang, Xiao‐Feng Wu   +2 more
wiley   +1 more source

Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley   +1 more source

<i>S</i>-Palmitoylation in Health and Disease. [PDF]

Biochemistry
Wong W, Hu M, Isaacson RL.
europepmc   +1 more source

Chemical Optimization of Temporin A–L Peptides: From Native Isoforms to Enhanced Antimicrobial Analogs

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino, Paolo Grieco, Francesco Merlino   +2 more
wiley   +1 more source

New Biobased Polyester Polyols With Tunable Tg Values From 4‐Vinylguaiacol‐Derived Monomers

ChemSusChem, Volume 19, Issue 15, 14 August 2026.
Biobased low‐molecular‐weight polyesters were obtained by ROCOP of guaiacol‐derived epoxides with cyclic anhydrides. Varying the length of the acyl moieties on the epoxides and the cyclic anhydride structures, it is possible to tune the Tg's within an 80 ºC wide temperature range.
Erika Zangelmi, Orlando Santoro, Raffaele Cucciniello, Francesco Della Monica, Lorella Izzo   +4 more
wiley   +1 more source

Correction: Acylation of Lysine 983 Is Sufficient for Toxin Activity of Bordetella pertussis Adenylate Cyclase. [PDF]

J Biol Chem
Basar T, Havlíček V, Bezoušková S, Hackett M, Ŝebo P.   +4 more
europepmc   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, Volume 13, Issue 43, 3 August 2026.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source