Results 211 to 220 of about 126,317 (283)

Mechanisms and functions of protein S-acylation

Nature Reviews Molecular Cell Biology
Over the past two decades, protein S-acylation (often referred to as S-palmitoylation) has emerged as an important regulator of vital signalling pathways. S-Acylation is a reversible post-translational modification that involves the attachment of a fatty
Francisco S Mesquita, Laurence Abrami, Maurine E Linder   +2 more
exaly   +2 more sources

Enzymatic acylation of blackcurrant (Ribes nigrum) anthocyanins and evaluation of lipophilic properties and antioxidant capacity of derivatives

Food Chemistry, 2019
Anthocyanin-rich fractions isolated from blackcurrant (Ribes nigrum L.) including delphinidin-3-O-glucoside, delphinidin-3-O-rutinoside, cyanidin-3-O-glucoside and cyanidin-3-O-rutinoside were enzymatically acylated with lauric acid.
Wei Yang, Maaria Kortesniemi, Xueying Ma   +2 more
exaly   +2 more sources

S-acylation regulates SQSTM1/p62-mediated selective autophagy

Autophagy, 2023
Macroautophagy/autophagy is a highly conserved metabolic process that degrades intracellular components and recycles bioenergetic substrates. SQSTM1/p62 (sequestosome 1) is a classical autophagy receptor that participates in selective autophagy to ...
Xue Huang, Lu Liu, Jia Yao, Changhai Lin, Tingxiu Xiang, Aimin Yang   +5 more
semanticscholar   +1 more source

Regiodivergent C-H Acylation of Arenes by Switching from Ionic to Radical Type Chemistry Using NHC-Catalysis.

Angewandte Chemie, 2023
The Friedel-Crafts acylation which belongs to the class of electrophilic aromatic substitutions is a highly valuable and versatile reaction in synthesis.
Jannik Reimler, Xiao‐Ye Yu, Nico Spreckelmeyer, C. Daniliuc, A. Studer   +4 more
semanticscholar   +1 more source

Ligand Relay Catalysis Enables Asymmetric Migratory Reductive Acylation of Olefins or Alkyl Halides.

Journal of the American Chemical Society, 2022
Design of ligands in transition-metal catalyzed reactions is challenging, especially in asymmetric transformations. With each step in the catalytic cycle promoted by its privileged ligand and different steps well-connected by dynamic ligand exchange ...
Xiaoli Jiang, Feng‐Tao Sheng, Yao-Wei Zhang, Gao Deng, Shaolin Zhu   +4 more
semanticscholar   +1 more source

Enzymatic acylation of raspberry anthocyanin: Evaluations on its stability and oxidative stress prevention.

Food Chemistry, 2021
Raspberry anthocyanins were isolated and purified by XAD-7HP macroporous resin and silica gel column chromatography. Anthocyanins were then acylated with methyl salicylate as catalyzed by lipase under reduced pressure, and the conversion rate was 84.26%.
Hui Teng, Y. Mi, H. Cao, Lei Chen
semanticscholar   +1 more source

An atlas of Arabidopsis protein S-Acylation reveals its widespread role in plant cell organisation and function

Nature Plants, 2022
S-acylation is the addition of a fatty acid to a cysteine residue of a protein. While this modification may profoundly alter protein behaviour, its effects on the function of plant proteins remains poorly characterized, largely as a result of the lack of
Manoj Kumar, P. Carr, Simon Turner
semanticscholar   +1 more source

Nucleophilic Acyl Substitution of Acyl Diimides

The Journal of Organic Chemistry, 2009
The nucleophilic acyl substitution of the acyl diimide intermediate formed by the oxidation of isoniazid was found to involve two methanol molecules in a six-membered cyclic transition state. Calculations were performed in the gas phase at the B3LYP/6-311+G(d,p)//B3LYP/6-31G(d) level of theory and solvation effects were included both explicitly and ...
Ruth I J, Amos, Carl H, Schiesser, Jason A, Smith, Brian F, Yates   +3 more
openaire   +2 more sources

Direct Enantioselective C(sp3)-H Acylation for the Synthesis of α-Amino Ketones.

Journal of the American Chemical Society, 2020
A direct enantioselective acylation of α-amino C(sp3)-H bonds with carboxylic acids has been achieved via the merger of transition metal and photoredox catalysis.
Xiaomin Shu, Leitao Huan, Qian-Wei Huang, Haohua Huo   +3 more
semanticscholar   +1 more source