Results 21 to 30 of about 98,046 (284)

Oxidative acylation of sulfoximines with methylarenes as an acyl donor [PDF]

open access: yesRSC Advances, 2015
An efficient direct oxidative acylation of sulfoximines with methylarenes as an acyl donor was finally achieved.
Junfeng Zhao   +4 more
openaire   +2 more sources

Detection and Analysis of S-Acylated Proteins via Acyl Resin-Assisted Capture (Acyl-RAC). [PDF]

open access: yesBio Protoc
Protein palmitoylation is a lipid modification where a palmitoyl group is covalently attached via a thioester linkage to one or more cysteines on a substrate protein. This modification, catalyzed by a group of enzymes named DHHC enzymes after their conserved Asp-His-His-Cys motif, plays a significant role in regulating the localization, stability, and ...
Abdulrahman DA, Veit M.
europepmc   +4 more sources

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz   +2 more
wiley   +1 more source

S‐Acyl and N‐Acyl Derivatives of Benzothiazole‐2‐thiol: An Example of Acyl Group Rearrangement. [PDF]

open access: yesChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Joung Hee Lee   +2 more
openaire   +3 more sources

Preparation of Translationally Competent tRNA by Direct Chemical Acylation [PDF]

open access: yes, 2010
Nonsense codon suppression for unnatural amino acid incorporation requires the preparation of a suppressor aminoacyl-tRNA. Chemical acylation strategies are general but inefficient and arduous. A recent report (J. Am. Chem. Soc.
Dougherty, Dennis A., Duffy, Noah H.
core   +2 more sources

Plasma membrane association by N-acylation governs PKG function in Toxoplasma gondii [PDF]

open access: yes, 2017
Cyclic GMP (cGMP)-dependent protein kinase (protein kinase G [PKG]) is essential for microneme secretion, motility, invasion, and egress in apicomplexan parasites, However, the separate roles of two isoforms of the kinase that are expressed by some ...
Brown, Kevin M   +2 more
core   +2 more sources

Supramolecular Chemistry in Metal–Organic Framework Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights synergies between reticular chemistry and supramolecular chemistry. The role of supramolecular interactions in determining framework…guest interactions and attempts to understand dynamic behavior in metal–organic frameworks (MOFs), particularly emphasizing the development of crystal sponges, studying reactions in frameworks and ...
Eugenia Miguel‐Casañ   +3 more
wiley   +1 more source

Unlocking the Essence of Lignin: High‐Performance Adhesives That Bond via Thiol‐Catechol Connectivities and Debond on Electrochemical Command

open access: yesAdvanced Materials, EarlyView.
A novel lignin‐inspired adhesive is presented, that combines the bonding strength of a structural adhesive with on‐demand electrochemical debonding, enabled by biomimetic thiol‐catechol connectivities. Voltage application of only 9 V facilitates electrochemical oxidation of catechols to quinones leading to guided detachment on command.
Keven Walter   +7 more
wiley   +1 more source

A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]

open access: yes, 2010
Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J.   +9 more
core   +2 more sources

Gold‐Catalyzed Synthesis of Fluorenones via Intramolecular C–H Arylation

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Starting from 2‐diazobenzophenones, a straightforward synthesis of valuable fluorenones via a gold‐catalyzed one‐pot oxidation, C–H activation, and cyclization is described. The addition of ascorbic acid, the correct selection of the counteranion of the 2‐diazobenzophenones, and the use of terpyridine as an auxiliary ligand are crucial for the reaction
Osvaldo Felipe López‐Saladino   +5 more
wiley   +1 more source

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