Results 101 to 110 of about 20,502 (253)
: Immune thrombotic thrombocytopenic purpura (iTTP) is primarily caused by immunoglobulin G (IgG)–type autoantibodies that bind and inhibit plasma ADAMTS13 activity and/or accelerate its clearance from circulation. Approximately 50% of patients with iTTP
Jingrui Sui +9 more
doaj +1 more source
BackgroundThrombotic microangiopathy (TMA) is a syndrome associated with hemolytic anemia, thrombocytopenia, and various organ disorders. Thrombotic thrombocytopenic purpura (TTP) is a disease that develops when a disintegrin-like and metalloproteinase ...
Yoko Takagi +12 more
doaj +1 more source
ADAMTS13: A New Link Between Thrombosis and Inflammation [PDF]
von Willebrand factor (VWF) levels are elevated and a disintegrin-like and metalloprotease with thrombospondin type I repeats–13 (ADAMTS13) activity is decreased in both acute and chronic inflammation.
Brill, Alexander +5 more
core +1 more source
Severe COVID‐19 is often compounded by a prothrombotic state that is associated with poor outcomes. In this investigation, we aimed to evaluate ADAMTS13 activity, von Willebrand factor level (VWF:Ag), and the corresponding ADAMTS13 activity/VWF:Ag ratio,
B. Henry +5 more
semanticscholar +1 more source
Expression of ADAMTS13 and PCNA in the Placentas of Gestational Diabetic Mothers
GDM is linked with overexpression of inflammatory cytokines and increased oxidative stress, leading to endothelial dysfunction and vascular disorder.
Süleyman Cemil Oğlak, M. Obut
semanticscholar +1 more source
Supplemental Digital Content is available in the text Acute kidney injury (AKI) is common after trauma, but contributory factors are incompletely understood.
William E Plautz +14 more
semanticscholar +1 more source
This study reports a rare case of bone marrow failure syndrome type 1 (BMFS1) caused by a novel de novo splicing mutation (c.1502+1G>A) in the SRP72 gene. The 6‐year‐old patient presented with aplastic anemia and pancytopenia. Genetic analysis identified the mutation, which was absent in both parents, confirming its de novo origin.
Wang Xiangwen +3 more
wiley +1 more source
Anti-A Disintegrin and Metalloproteinase with a ThromboSpondin type 1 motif, member 13 (ADAMTS13) autoantibodies cause a severe ADAMTS13 deficiency in immune-mediated thrombotic thrombocytopenic purpura (iTTP). ADAMTS13 consists of a metalloprotease (M),
K. Kangro +15 more
semanticscholar +1 more source
ABSTRACT Aim This study aimed to evaluate whether human dental pulp stem cells (DPSCs), after long‐term biobanking (7–8 years), retain their pro‐angiogenic properties and can be used to engineer vascularised tissues, addressing their potential for clinical translation in regenerative dentistry.
Shuntaro Yamada +10 more
wiley +1 more source
Pseudotumor Cerebri and Hemolytic Uremic Syndrome, A Rare Association
ABSTRACT Hemolytic uremic syndrome can present with central nervous system involvement. Idiopathic intracranial hypertension (IIH) is among the possible neurological manifestations of HUS, and clinicians should remain vigilant for extrarenal complications while treating patients with HUS.
Aasim Ali +6 more
wiley +1 more source

