Results 11 to 20 of about 5,085,110 (360)
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity [PDF]
Nature reviews. Immunology, 2021 Payel Roy, Marco Orecchioni, Klaus Ley
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Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine
Nature Immunology, 2022 Despite the success of the BNT162b2 mRNA vaccine, the immunological mechanisms that underlie its efficacy are poorly understood. Here we analyzed the innate and adaptive responses to BNT162b2 in mice, and show that immunization stimulated potent antibody
Chunfeng Li +23 more
semanticscholar +1 more source
Periphery and brain, innate and adaptive immunity in Parkinson’s disease
Acta Neuropathologica, 2021 Parkinson’s disease (PD) is a neurodegenerative disorder where alpha-synuclein plays a central role in the death and dysfunction of neurons, both, in central, as well as in the peripheral nervous system.
A. Harms +2 more
semanticscholar +1 more source
Platelet and Megakaryocyte Roles in Innate and Adaptive Immunity
Circulation Research, 2022 Classically, platelets have been described as the cellular blood component that mediates hemostasis and thrombosis. This important platelet function has received significant research attention for >150 years.
Milka Koupenova +2 more
semanticscholar +1 more source
Understanding Early-Life Adaptive Immunity to Guide Interventions for Pediatric Health
Frontiers in Immunology, 2021 Infants are capable of mounting adaptive immune responses, but their ability to develop long-lasting immunity is limited. Understanding the particularities of the neonatal adaptive immune system is therefore critical to guide the design of immune-based ...
E. C. Semmes +5 more
semanticscholar +1 more source
Exploring the pre-immune landscape of antigen-specific T cells
Genome Medicine, 2018 Background Adaptive immune responses to newly encountered pathogens depend on the mobilization of antigen-specific clonotypes from a vastly diverse pool of naive T cells.
Mikhail V. Pogorelyy +11 more
doaj +1 more source
'Towards a Conceptual Framework for Innate Immunity' [PDF]
, 2005 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core +3 more sources
NLRP3 Inflammasome: Checkpoint Connecting Innate and Adaptive Immunity in Autoimmune Diseases
Frontiers in Immunology, 2021 Autoimmune diseases are a broad spectrum of human diseases that are characterized by the breakdown of immune tolerance and the production of autoantibodies.
Yiwen Zhang +3 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Spondyloarthritis (SpA) comprises a number of inflammatory rheumatic diseases with overlapping clinical manifestations. Strong association with several HLA-I alleles and T cell infiltration into an inflamed joint suggest involvement of T cells in SpA ...
Ekaterina A. Komech +20 more
doaj +1 more source
Intestinal macromolecular transport supporting adaptive immunity [PDF]
, 2019 The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
core +2 more sources