Results 21 to 30 of about 1,761,502 (294)

Adaptive Immunity to Fungi [PDF]

Annual Review of Immunology, 2012
Only a handful of the more than 100,000 fungal species on our planet cause disease in humans, yet the number of life-threatening fungal infections in patients has recently skyrocketed as a result of advances in medical care that often suppress immunity intensely.
Marcel, Wüthrich, George S, Deepe, Bruce, Klein   +2 more
openaire   +2 more sources

Adaptive immunity in invertebrates: a straw house without a mechanistic foundation [PDF]

, 2007
Recently claims have been made for radical new insights in the field of invertebrate immunology that involve memory, specificity and/or maternal transfer of immunocompetence.
Smith, Valerie J., Hauton, Chris
core   +1 more source

TCR repertoire profiling revealed antigen-driven CD8+ T cell clonal groups shared in synovial fluid of patients with spondyloarthritis

Frontiers in Immunology, 2022
Spondyloarthritis (SpA) comprises a number of inflammatory rheumatic diseases with overlapping clinical manifestations. Strong association with several HLA-I alleles and T cell infiltration into an inflamed joint suggest involvement of T cells in SpA ...
Ekaterina A. Komech, Ekaterina A. Komech, Anastasia D. Koltakova, Anna A. Barinova, Anna A. Barinova, Anastasia A. Minervina, Maria A. Salnikova, Evgeniya I. Shmidt, Tatiana V. Korotaeva, Elena Y. Loginova, Shandor F. Erdes, Ekaterina A. Bogdanova, Ekaterina A. Bogdanova, Mikhail Shugay, Mikhail Shugay, Sergey Lukyanov, Sergey Lukyanov, Yury B. Lebedev, Yury B. Lebedev, Ivan V. Zvyagin, Ivan V. Zvyagin   +20 more
doaj   +1 more source

Curating the innate immunity interactome [PDF]

, 2010
peer-reviewedBackground: The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks.
Laird, Matthew R, Anastasia Sribnaia, Winsor, Geoffrey L., Lynn, David J, Giselle Ring, Foroushani, Amir K., Laird, Matthew R., Que, Jaimmie, Geoffrey L Winsor, Robert EW Hancock, Sribnaia, Anastasia, Hancock, Robert E.W., Ring, Giselle, Melissa Yau, Fiona SL Brinkman, Calvin Chan, Jaimmie Que, David J Lynn, Brinkman, Fiona S. L., Naseer, Misbah, Matthew R Laird, Yau, Melissa, Lo, Raymond, Raymond Lo, Chan, Calvin, Wee, Kathleen, Winsor, Geoffrey L, Breuer, Karin, Kathleen Wee, Amir K Foroushani, Hancock, R. E. W. (Robert E. W.), Brinkman, Fiona S., Misbah Naseer, Karin Breuer, Lynn, David J.   +34 more
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Comparative Analysis of B-Cell Receptor Repertoires Induced by Live Yellow Fever Vaccine in Young and Middle-Age Donors

Frontiers in Immunology, 2018
Age-related changes can significantly alter the state of adaptive immune system and often lead to attenuated response to novel pathogens and vaccination.
Alexey N. Davydov, Anna S. Obraztsova, Anna S. Obraztsova, Mikhail Y. Lebedin, Maria A. Turchaninova, Maria A. Turchaninova, Maria A. Turchaninova, Dmitriy B. Staroverov, Dmitriy B. Staroverov, Ekaterina M. Merzlyak, Ekaterina M. Merzlyak, George V. Sharonov, George V. Sharonov, Olga Kladova, Mikhail Shugay, Mikhail Shugay, Mikhail Shugay, Mikhail Shugay, Olga V. Britanova, Olga V. Britanova, Olga V. Britanova, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov   +25 more
doaj   +1 more source

Autophagy and adaptive immunity [PDF]

Immunology, 2010
SummaryAutophagy plays an important role in maintaining intracellular homeostasis by promoting the transit of cytoplasmic material, such as proteins, organelles and pathogens, for degradation within acidic organelles. Yet, in immune cells, autophagy pathways serve an additional role in facilitating intracellular surveillance for pathogens and changes ...
Victoria L, Crotzer, Janice S, Blum
openaire   +2 more sources

Dendritic cell regulation of immunity to Leishmania donovani [PDF]

, 2010
Dendritic cells lie at the interface of innate and adaptive immunity, critically contributing to the generation of an antigen-specific immune response.
Owens, Benjamin M.J.
core   +6 more sources

The long subclinical phase of Mycobacterium avium ssp. paratuberculosis infections explained without adaptive immunity [PDF]

, 2015
Mycobacterium avium ssp. paratuberculosis (MAP) is an infection of the ruminant intestine. In cows, a long subclinical phase with no or low intermittent shedding precedes the clinical phase with high shedding.
Klinkenberg, D., Sub Immunologie, Klinkenberg, Don, Koets, Ad, Ad Koets, Don Klinkenberg, Koets, A.P., FAH SIB, Infection & Immunity   +8 more
core   +2 more sources

Targeting Host Innate and Adaptive Immunity to Achieve the Functional Cure of Chronic Hepatitis B

, 2020
Despite the availability of an effective preventive vaccine for hepatitis B virus (HBV) for over 38 years, chronic HBV (CHB) infection remains a global health burden with around 257 million patients. The ideal treatment goal for CHB infection would be to
Michinori Kohara, Kyoko Tsukiyama-Kohara, Sayeh Ezzikouri, Soumaya Benjelloun, Mohammad Enamul Hoque Kayesh   +4 more
core   +1 more source

T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis. [PDF]

, 2015
There is an urgent need for a better understanding of adaptive immunity to Burkholderia pseudomallei, the causative agent of melioidosis that is frequently associated with sepsis or death in patients in Southeast Asia and Northern Australia.
Sumonwiriya, M, Makinde, Julia, Reynolds, Catherine, Altmann, D, Quigley, K, Rinchai, Darawan, Overbeek, S, Boyton, R, Yos, Pagnarith, Jenjaroen, Kemajittra, Maillere, Bernard, Manji, J, Yos, P, Reynolds, C, Musson, Julie, Overbeek, Saskia, Manji, Jiten, Spink, N, Bancroft, Gregory, Musson, J, Dunachie, S, Quigley, Kathryn, Bancroft, G, Goudet, Amélie, Wuthiekanun, Vanaporn, Wuthiekanun, V, Altmann, Daniel, Robinson, John, Lertmemongkolchai, Ganjana, Makinde, J, Rinchai, D, Robinson, J, Lertmemongkolchai, G, Holden, Matthew, Maillere, B, Dunachie, Susanna, Goudet, A, Holden, M, Jenjaroen, K, Spink, Natasha, Boyton, Rosemary, Sumonwiriya, Manutsanun   +41 more
core   +1 more source