Results 101 to 110 of about 5,867,069 (283)
Cytokine-Induced Memory-Like NK Cells: From the Basics to Clinical Applications
Frontiers in Immunology, 2022 Natural killer (NK) cells are lymphocytes with a key role in the defense against viral infections and tumor cells. Although NK cells are classified as innate lymphoid cells (ILCs), under certain circumstances they exhibit adaptive and memory-like ...
I. Terrén +5 more
semanticscholar +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Adaptive Natural Killer Cells Integrate Interleukin-18 during Target-Cell Encounter
Frontiers in Immunology, 2018 Human cytomegalovirus (HCMV) infection induces adaptations in the natural killer (NK)-cell compartment. Expanded subsets of adaptive NK cells display potent effector functions against cellular targets, despite their apparent unresponsiveness to ...
Quirin Hammer +4 more
doaj +1 more source
NK Cells Under Hypoxia: The Two Faces of Vascularization in Tumor and Pregnancy
Frontiers in Immunology, 2022 Environmental conditions greatly shape the phenotype and function of immune cells. Specifically, hypoxic conditions that exist within tissues and organs have been reported to affect both the adaptive and the innate immune system.
Irene Garcés-Lázaro +4 more
doaj +1 more source
Hidden talents of natural killers: NK cells in innate and adaptive immunity [PDF]
The EMBO Reports, 2009 Natural killer (NK) cells are innate immune lymphocytes capable of killing target cells and producing immunoregulatory cytokines. Herein, we discuss recent studies that indicate that NK cells span the conventional boundaries between innate and adaptive immunity.
Megan A, Cooper +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Frontiers in Immunology, 2018 In human natural killer (NK) cells, human cytomegalovirus (HCMV) has been shown to be a driving force capable of inducing the expansion of a highly differentiated NKG2C+CD57+ subset, persisting over time in both HCMV+ healthy subjects and umbilical cord ...
Letizia Muccio +12 more
doaj +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
The Role of Natural Killer Cells in the Immune Response in Kidney Transplantation
Frontiers in Immunology, 2020 Natural killer cells (NK) represent a population of lymphocytes involved in innate immune response. In addition to their role in anti-viral and anti-tumor defense, they also regulate several aspects of the allo-immune response in kidney transplant ...
Paola Pontrelli +6 more
doaj +1 more source
IL-15 participates in the respiratory innate immune response to influenza virus infection. [PDF]
PLoS ONE, 2012 Following influenza infection, natural killer (NK) cells function as interim effectors by suppressing viral replication until CD8 T cells are activated, proliferate, and are mobilized within the respiratory tract.
Katherine C Verbist +4 more
doaj +1 more source