Results 91 to 100 of about 3,973,865 (282)

Potential of a compact low energy proton accelertor for medical applications [PDF]

This thesis explores the potential of a compact low energy (
Ratcliffe, Naomi
core   +3 more sources

Impact of reduced robustness settings on the necessity for proton therapy treatment plan adaptation in head-and-neck cancer patients

Physics and Imaging in Radiation Oncology
Background and purpose: Robust optimization mitigates the effects of range and setup uncertainties in intensity–modulated proton therapy (IMPT) through robustness settings. However, it increases the dose to organs-at-risk (OARs).
Brian Zapien-Campos, Dirk Wagenaar, Tim Franssen, Hans Verbeek, Stefan Both, Peter Dendooven   +5 more
doaj   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

Proton dose calculation on scatter‐corrected CBCT image: Feasibility study for adaptive proton therapy

Medical Physics, 2015
Purpose:To demonstrate the feasibility of proton dose calculation on scatter‐corrected cone‐beam computed tomographic (CBCT) images for the purpose of adaptive proton therapy.Methods:CBCT projection images were acquired from anthropomorphic phantoms and a prostate patient using an on‐board imaging system of an Elekta infinity linear accelerator.
Yang-Kyun, Park, Gregory C, Sharp, Justin, Phillips, Brian A, Winey   +3 more
openaire   +2 more sources

Dosimetric advantages of proton therapy compared with photon therapy using an adaptive strategy in cervical cancer [PDF]

Acta Oncologica, 2016
Background Image-guided adaptive proton therapy (IGAPT) can potentially be applied to take into account interfraction motion while limiting organ at risk (OAR) dose in cervical cancer radiation therapy (RT). In this study, the potential dosimetric advantages of IGAPT compared with photon-based image-guided adaptive RT (IGART) were investigated ...
Schoot, A.J.A.J. van de, Boer, P. de, Crama, K.F., Visser, J., Stalpers, L.J.A., Rasch, C.R.N., Bel, A.   +6 more
openaire   +4 more sources

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

Adaptive Proton Therapy Using CBCT-Guided Digital Twins

ArXiv
This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its effectiveness and reduced treatment duration.
Chang, Chih-Wei, Tian, Zhen, Qiu, Richard L. J., McGinnis, H. Scott, Bohannon, Duncan, Patel, Pretesh, Wang, Yinan, Yu, David S., Patel, Sagar A., Zhou, Jun, Yang, Xiaofeng   +10 more
openaire   +3 more sources

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Generation and evaluation of anatomy-preserving virtual CT for online adaptive proton therapy.

Medical Physics (Lancaster)
BACKGROUND Daily CTs generated by CBCT correction are required for daily replanning in online-adaptive proton therapy (APT) to effectively deal with inter-fractional changes.
S. Kaushik, Jakob Ödén, D. Sharma, Albin Fredriksson, I. Toma-Dasu   +4 more
semanticscholar   +1 more source