Results 91 to 100 of about 44,966 (284)

Innovative approaches in precision radiation oncology: advanced imaging technologies and challenges which shape the future of radiation therapy

Frontiers in Medicine
Radiation oncology is undergoing a transformative shift toward precision medicine through unprecedented advances in imaging technologies that enable increasingly personalized and adaptive cancer treatment.
Yue Yan, Yue Yan, Yue Yan, Daniel A. Alexander, Daniel A. Alexander, Bryan P. Bednarz, Lawrence F. Bronk, Huixiao Chen, David J. Gladstone, David J. Gladstone, David J. Gladstone, Bin Han, Christopher M. Iannuzzi, Yuting Li, Ngoc Nguyen, Natasha Mulenga, Natalie N. Viscariello, Yuenan Wang, Joseph Weygand, Joseph Weygand, Yana Zlateva, Fada Guan   +21 more
doaj   +1 more source

Infectious diseases and autoimmunity [PDF]

, 2011
Introduction: Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the ...
Deidda, Silvia, Delitala, Giuseppe, Delogu, Lucia Gemma, Manetti, Roberto   +3 more
core   +1 more source

Smart Face Masks as Wearable Respiratory Sensors: A Review of Sensor Technologies, Materials, and Future Directions

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in smart face masks that actively monitor breathing. By integrating humidity, gas, temperature, pressure, strain, and triboelectric sensors, these masks track key respiratory parameters in real time. The article summarizes sensor mechanisms, compares performance across studies, and discusses challenges and future ...
Negin Faramarzi, Naseeh Backer Kannanthodi, Alice Nicole Casling, Babar Ali, Samira Lakouraj Mansouri, Alessandro Giuseppe D'aloia, Hossein Cheraghi Bidsorkhi, Maria Sabrina Sarto   +7 more
wiley   +1 more source

An adaptive proton FLASH therapy using modularized pin ridge filter

Medical Physics
AbstractBackgroundIn our previous study, we developed a modular pin ridge filter (pRF) design framework to streamline assembly, enabling the fast manufacture of custom filters optimized for single‐energy proton FLASH planning.PurposeIn this paper, we propose a method to optimize adaptive proton FLASH therapy (ADP‐FLASH) using modularized pRFs by ...
Zafar, Ahmal Jawad, Yang, Xiaofeng, Diamond, Zachary, Sibo, Tian, Yu, David, Patel, Pretesh R., Zhou, Jun   +6 more
openaire   +2 more sources

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Implementation of a Compact Spot-Scanning Proton Therapy System in a GPU Monte Carlo Code to Support Clinical Routine

Frontiers in Physics, 2020
The purpose of this work was to implement a fast Monte Carlo dose calculation tool, Fred, in the Maastro proton therapy center in Maastricht (Netherlands) to complement the clinical treatment planning system.
Jan Gajewski, Angelo Schiavi, Angelo Schiavi, Nils Krah, Nils Krah, Gloria Vilches-Freixas, Antoni Rucinski, Vincenzo Patera, Vincenzo Patera, Ilaria Rinaldi   +9 more
doaj   +1 more source

Uncoupling protein 2: a key player and a potential therapeutic target in vascular diseases [PDF]

, 2017
Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein that belongs to the uncoupling protein family and plays an important role in lowering mitochondrial membrane potential and dissipating metabolic energy with prevention of oxidative ...
Forte, Maurizio, Migliarino, Serena, Perelli, Marika, Pierelli, Giorgia, Rubattu, Speranza, Stanzione, Rosita, Volpe, Massimo   +6 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Metabolic Dependencies in Pancreatic Cancer. [PDF]

, 2018
Pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer with a long-term survival rate under 10%. Available cytotoxic chemotherapies have significant side effects, and only marginal therapeutic efficacy. FDA approved drugs currently used against
Brody, Jonathan R., Vaziri-Gohar, Ali, Winter, Jordan M., Zarei, Mahsa   +3 more
core   +1 more source

The use of non-selective beta-blockers in patients with cirrhosis: more doubts than certainties [PDF]

, 2017
In conclusion, prospective RCT would be needed on the use of NSBBs in decompensated cirrhotic patients with ascites however these trials are difficult to organize and will need a large sample size.
Di Gregorio, Vincenza, D’Ambrosio, Daria, Lattanzi, Barbara, Merli, Manuela   +3 more
core   +1 more source