Results 101 to 110 of about 44,966 (284)

Multi-institutional experimental validation of online adaptive proton therapy workflows

Physics in Medicine & Biology
AbstractObjective.To experimentally validate two online adaptive proton therapy (APT) workflows using Gafchromic EBT3 films and optically stimulated luminescent dosimeters (OSLDs) in an anthropomorphic head-and-neck phantom.Approach.A three-field proton plan was optimized on the planning CT of the head-and-neck phantom with 2.0 Gy(RBE) per fraction ...
Mislav Bobić, Evangelia Choulilitsa, Hoyeon Lee, Katarzyna Czerska, Jeppe B Christensen, Alexandre Mayor, Sairos Safai, Brian A Winey, Damien C Weber, Antony J Lomax, Harald Paganetti, Konrad P Nesteruk, Francesca Albertini   +12 more
openaire   +3 more sources

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

Advanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno, Andrea Escudero, Oscar Ferreira Silvestre, José Manuel Terrés, Mónica Gorbe, Eva Garrido, Carlos Renero‐Lecuna, Judith Langer, María Alfonso, Javier Ibañez, Félix Sancenón, Roberto Cao‐Milán, Luis M. Liz‐Marzán, Alba García‐Fernández, Andy Hernández‐Montoto, Ramón Martínez‐Máñez   +15 more
wiley   +1 more source

Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain

Advanced Materials, EarlyView.
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha, Bilguun Nurzed, Mostafa Berangi, Andre Kuehne, Helmar Waiczies, Igor Fabian Tellez Ceja, Xiang Hu, Thomas Gladytz, Lisa Krenz, Dave Huebler, Beate Endemann, Claudia Brockmann, Ebba Beller, Oliver Stachs, Thoralf Niendorf   +14 more
wiley   +1 more source

A treatment-site-specific evaluation of commercial synthetic computed tomography solutions for proton therapy

Physics and Imaging in Radiation Oncology
Background and purpose: Despite the superior dose conformity of proton therapy, the dose distribution is sensitive to daily anatomical changes, which can affect treatment accuracy.
Ping Lin Yeap, Yun Ming Wong, Kang Hao Lee, Calvin Wei Yang Koh, Kah Seng Lew, Clifford Ghee Ann Chua, Andrew Wibawa, Zubin Master, James Cheow Lei Lee, Sung Yong Park, Hong Qi Tan   +10 more
doaj   +1 more source

Clustomesogen Showing Sub‐Zero Liquid Crystal Properties: Supramolecular Assembly Between Cs2[Mo6Ii8(OCOC2F5)6] and Hexaethylenoxide Containing Mesogenic Dimers

Advanced Materials, EarlyView.
Associating a red‐NIR phosphorescent octahedral hexanuclear molybdenum cluster compound with hexaethyleneoxide chains bearing mesogenic units on both ends leads to an emissive hybrid liquid crystal showing mesomorphism on a very unusual temperature range down to −25°C.
Killiann Heinz, Jeanne Rebours, Zoulikha Zerrouqi, Noée Dumait, Maria Amela‐Cortes, Nikolai Scheuring, Sara Simonovska, Sebastian Marino, Max Ebert, Stéphane Cordier, Sabine Laschat, Yann Molard   +11 more
wiley   +1 more source

Plasmonic Nanomachines: Creating Local Potential Gradients and Motions

Advanced Materials, EarlyView.
Plasmonic nanomachines can generate optical, thermal, and chemical potential gradients to drive directional rectilinear, rotational, and twisting motions at the nanometer scale. The integration of multimodal plasmonic forces with functional materials and programmed structural distortions enables precise spatiotemporal actuation, thereby providing a ...
Yoonhee Kim, Soohyun Ji, Donghyun Choi, Jwa‐Min Nam   +3 more
wiley   +1 more source

Ultra-low field magnetic resonance breast imaging in prone and seated positions for radiation therapy

Physics and Imaging in Radiation Oncology
Background & purpose: The aim of this first-in-human study was to investigate the potential of ultra-low field (ULF) magnetic resonance imaging (MRI) at 6.5 mT for breast imaging in healthy female participants in prone and seated positions for ...
Friderike K. Longarino, Sheng Shen, Neha Koonjoo, Torben P.P. Hornung, Rachel B. Jimenez, Elie K. Mehanna, John T. Burge, Zoelle Wilson, Kathryn E. Keenan, Thomas R. Bortfeld, Matthew S. Rosen, Susu Yan   +11 more
doaj   +1 more source

Strategies of dose escalation in the treatment of locally advanced non-small cell lung cancer: image guidance and beyond

Frontiers in Oncology, 2014
Radiation dose in the setting of chemo-radiation for locally advanced non-small cell lung cancer (NSCLC) has been historically limited by the risk of normal tissue toxicity and this has been hypothesized to correlate with the poor results in regard to ...
Alexander eChi, Nam Phong Nguyen, James S Welsh, William eTse, Manish eMonga, Olusola eOduntan, Mohammed eAlmubarak, John eRogers, Scot C Remick, David eGius   +9 more
doaj   +1 more source

Probing the quantum vacuum with ultra intense laser pulses

, 2014
This article presents: 1) The theoretical background of strong field physics and vacuum structure and stability; 2) The instrumental developments in the area of pulse lasers and considers the physics case for ultra intense laser facilities; and 3 ...
Hegelich, B. Manuel, Mourou, Gerard, Rafelski, Johann   +2 more
core   +1 more source

Bioelectrical Interfaces Beyond Excitable Cells: Cancer, Aging, and Gene Expression Modulation

Advanced Materials Interfaces, EarlyView.
ABSTRACT The investigation of biological conductivity has evolved from its classical foundation based on ionic fluxes underpinning cardiac and neuronal excitability to a multifaceted regulator of cellular physiology. Traditional approaches for probing electrical events in living matter focused largely on action potentials recording.
Paolo Cadinu, Matthew K. Burgess, Catarina Franco Jones, Marzia Iarossi, Manuel Schröter, Nako Nakatsuka, Mustafa B. A. Djamgoz, Gil Gonçalves, Sidahmed Abayzeed, Paola Sanjuán‐Alberte, Paula M. Mendes, Frankie J. Rawson, Malavika Nair, Michael Levin, Rosalia Moreddu   +14 more
wiley   +1 more source