Results 51 to 60 of about 63,155 (105)

Engineering and comparison of cas12a‐based genome editing systems in plants

open access: yesThe Plant Journal, Volume 123, Issue 5, September 2025.
SUMMARY While Cas9 and Cas12a are both RNA‐guided endonucleases used for genome editing, only Cas12a is able to process pre‐crRNA via its additional ribonuclease activity. This feature reduces the complexity of Cas12a versus Cas9‐based genome editing systems thus providing an attractive alternative for generating site‐specific mutations in plants. Here
Martin Bircheneder, Martin Parniske
wiley   +1 more source

Comparing school leaders' experiences of research use in England, Scotland and Germany

open access: yesReview of Education, Volume 13, Issue 1, April 2025.
Abstract In some countries it is common for policy makers to advocate research use by practitioners as a means to bring about school development. Yet, despite their increasing sophistication, the enactment of protocols for using research is problematic and, even in optimal environments, practitioners have difficulty mobilising research findings to ...
Peter Kelly, Anna Beck, Susann Hofbauer
wiley   +1 more source

DynaGUI - Konzepte und Methoden zur Entwicklung adaptiver und intuitiver Benutzeroberflächen

open access: yes, 2022
Ziel des Projektes "DynaGUI" ist die Erforschung von Konzepten und Methoden zur Entwicklung adaptiver und intuitiver Benutzeroberflächen. Dies beinhaltet unter anderem die Erarbeitung von Vorgehensweisen zur Analyse der Funktionalität und der ...
Diener, Holger   +2 more
core   +1 more source

General and special education teachers' attitudes towards evidence‐based practice

open access: yesJournal of Research in Special Educational Needs, Volume 25, Issue 2, Page 323-340, April 2025.
Abstract In the context of special and inclusive education, applying evidence‐based practice (EBP) is important for providing equal access to effective and efficient education for students, regardless of their ability status. However, there is a relevant research‐practice gap in this area.
Lea Rüger, David Scheer
wiley   +1 more source

The Plausibility of Klafki's Model of Exemplary Teaching

open access: yesEducational Theory, Volume 75, Issue 1, Page 81-106, February 2025.
Abstract In this article Antti Moilanen assesses criticisms of Wolfgang Klafki's model of exemplary teaching made by Meinert Meyer and Hilbert Meyer and by Chi‐Hua Chu. “Exemplary teaching” is a style of discovery‐based teaching in which students study concrete examples of general principles in such a way that they acquire transferable knowledge and ...
Antti Moilanen
wiley   +1 more source

Unterrichten mit MatheBattle: Eine Lehrkräftefortbildung zur Gestaltung adaptiver Übungsphasen

open access: yes
Adaptiver Unterricht gilt als vielversprechender Ansatz, der Heterogenität der Lernenden zu begegnen. Übungsphasen, die der Festigung mathematischer Fähigkeiten dienen, bieten hierfür geeignete Ansatzpunkte.
Paravicini, Walther   +3 more
core   +1 more source

A quantitative assay for the efficiency of RNA‐guided genome editing in plants

open access: yesThe Plant Journal, Volume 119, Issue 5, Page 2564-2577, September 2024.
SUMMARY RNA‐guided endonucleases originating from the bacterial CRISPR/Cas system are a versatile tool for targeted gene editing. To determine the functional relevance of a gene of interest, deletion of the entire open reading frame (ORF) by two independent double‐strand breaks (DSBs) is particularly attractive. This strategy greatly benefits from high
Martin Bircheneder   +3 more
wiley   +1 more source

Three‐dimensional model for improvement of endometriosis care (3D‐E)

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 165, Issue 2, Page 416-423, May 2024.
Abstract Objective Endometriosis affects approximately 10% of women of reproductive age and leads to significant morbidity and financial burden. Consequently, countries such as France and Germany are formulating strategies to combat endometriosis. In this study, we propose the implementation of our three‐dimensional model (3D‐E) to raise awareness ...
Stefan Lukac   +8 more
wiley   +1 more source

Modellierung adaptiver eingebetteter Systeme

open access: yes, 2005
Ein elementares Problem bei der Entwicklung adaptiver Systeme besteht darin, dass das Adaptionsverhalten eines Systems durch sehr komplexe Zusammenhänge bestimmt ist.
Wörz, Philipp   +2 more
core   +1 more source

Editorial: Bildung für eine digitale Zukunft. [PDF]

open access: yesZ Erziehwiss, 2021
Scheiter K, Gogolin I.
europepmc   +1 more source

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