Results 1 to 10 of about 40,794 (233)

Identification and Spatiotemporal Expression of Adenosine Deaminases Acting on RNA (ADAR) during Earthworm Regeneration: Its Possible Implication in Muscle Redifferentiation [PDF]

open access: goldBiology, 2020
Adenosine deaminases acting on RNA (ADAR) catalyze the hydrolytic deamination of adenosine (A) to produce inosine (I) in double-stranded RNA substrates.
Yoo Bin Yoon   +4 more
doaj   +2 more sources

ANALYSIS OF FAST NEUTRON TRANSPORT IN CHLORIDE SALTS USING MONTE CARLO METHOD

open access: yesActa Polytechnica CTU Proceedings, 2020
The aim of this paper is to present results of fast neutron behavior analysis within the chloride salts environment using simulations based on Monte Carlo method (MCNP 6.2).
Ondřej Šťastný   +4 more
doaj   +1 more source

Elevated ADAR expression is significantly linked to shorter overall survival and immune infiltration in patients with lung adenocarcinoma

open access: yesMathematical Biosciences and Engineering, 2023
To date, few studies have investigated whether the RNA-editing enzymes adenosine deaminases acting on RNA (ADARs) influence RNA functioning in lung adenocarcinoma (LUAD).
Siqi Hu   +3 more
doaj   +1 more source

Identification of the pathogenic variants in three Chinese families with dyschromatosis symmetrica hereditaria [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To analyze the clinical features and to identify the pathogenic variants in three Chinese families with dyschromatosis symmetrica hereditaria (DSH).
YANG Xueting, GUO Kexin, SUN Yang, WANG Rongrong, MA Donglai, ZHANG Xue
doaj   +1 more source

ADAR expression and copy number variation in patients with advanced gastric cancer

open access: yesBMC Gastroenterology, 2020
Background Gastric cancer (GC) is a world health problem and it is the third leading cause of cancer deaths worldwide. The current practice for prognosis assessment in GC is based on radiological and pathological criteria and they may not result in an ...
Javad Behroozi   +3 more
doaj   +1 more source

The A to I editing landscape in melanoma and its relation to clinical outcome

open access: yesRNA Biology, 2022
RNA editing refers to non-transient RNA modifications that occur after transcription and prior to translation by the ribosomes. RNA editing is more widespread in cancer cells than in non-transformed cells and is associated with tumorigenesis of various ...
Austeja Amweg   +11 more
doaj   +1 more source

Dynamic hyper-editing underlies temperature adaptation in Drosophila. [PDF]

open access: yesPLoS Genetics, 2017
In Drosophila, A-to-I editing is prevalent in the brain, and mutations in the editing enzyme ADAR correlate with specific behavioral defects. Here we demonstrate a role for ADAR in behavioral temperature adaptation in Drosophila.
Ilana Buchumenski   +6 more
doaj   +1 more source

Programmable RNA editing with endogenous ADAR enzymes – a feasible option for the treatment of inherited retinal disease?

open access: yesFrontiers in Molecular Neuroscience, 2023
RNA editing holds great promise for the therapeutic correction of pathogenic, single nucleotide variants (SNV) in the human transcriptome since it does not risk creating permanent off-targets edits in the genome and has the potential for innovative ...
Julia-Sophia Bellingrath   +5 more
doaj   +1 more source

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

open access: yesBMC Biology, 2020
Background In fly brains, the Drosophila Adar (adenosine deaminase acting on RNA) enzyme edits hundreds of transcripts to generate edited isoforms of encoded proteins.
Anzer Khan   +8 more
doaj   +1 more source

The Advantage of Evidential Attributes in Social Networks [PDF]

open access: yes, 2017
Nowadays, there are many approaches designed for the task of detecting communities in social networks. Among them, some methods only consider the topological graph structure, while others take use of both the graph structure and the node attributes.
adar   +7 more
core   +3 more sources

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