Link prediction in multiplex networks via triadic closure [PDF]
Link prediction algorithms can help to understand the structure and dynamics of complex systems, to reconstruct networks from incomplete data sets and to forecast future interactions in evolving networks. Available algorithms based on similarity between nodes are bounded by the limited amount of links present in these networks.
Aleta, Alberto+4 more
arxiv +7 more sources
Extending adamic adar for cold-start problem in link prediction based on network metrics
The cold-start problem is a condition for a new node to join a network with no available information or an isolated node. Most studies use topological network information with the Triadic Closure principles to predict links in future networks.
Herman Yuliansyah+2 more
doaj +2 more sources
QCD3 dualities and the F-theorem [PDF]
There has recently been a surge of new ideas and results for 2+1 dimensional gauge theories. We consider a recently proposed duality for 2+1 dimensional QCD, which predicts a symmetry-breaking phase.
Adar Sharon
doaj +2 more sources
Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila [PDF]
ADAR RNA editing enzymes are high-affinity dsRNA-binding proteins that deaminate adenosines to inosines in pre-mRNA hairpins and also exert editing-independent effects.
Patricia Deng+11 more
openalex +2 more sources
Site-specific regulation of RNA editing with ribose-modified nucleoside analogs in ADAR guide strands [PDF]
Adenosine Deaminases Acting on RNA (ADARs) are enzymes that catalyze the conversion of adenosine to inosine in RNA duplexes. These enzymes can be harnessed to correct disease-causing G-to-A mutations in the transcriptome because inosine is translated as ...
Victorio Jauregui Matos+6 more
openalex +2 more sources
Lessons from discovery of true ADAR RNA editing sites in a human cell line
Background Conversion or editing of adenosine (A) into inosine (I) catalyzed by specialized cellular enzymes represents one of the most common post-transcriptional RNA modifications with emerging connection to disease.
Fang Wang+9 more
doaj +2 more sources
ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses
hnRNPC prevents release of inverted-repeat Alu double-stranded RNA into the cytosol by masking cryptic splice sites. Herzner et al. found that deficiency in hnRNPC led to dysregulation of splicing and increased abundance of intronic double-stranded RNA ...
Anna‐Maria Herzner+13 more
openalex +2 more sources
An engineered U7 small nuclear RNA scaffold greatly increases ADAR-mediated programmable RNA base editing [PDF]
Custom RNA base editing exploiting the human Adenosine Deaminase Acting on RNA (ADAR) enzyme may enable therapeutic gene editing without DNA damage or use of foreign proteins.
Susan M. Byrne+10 more
doaj +2 more sources
Charting and probing the activity of ADARs in human development and cell-fate specification [PDF]
Adenosine deaminases acting on RNA (ADARs) impact diverse cellular processes and pathological conditions, but their functions in early cell-fate specification remain less understood.
Amir Dailamy+10 more
doaj +2 more sources
VIRMA promotes NSCLC progression by modifying ADAR m6A and increasing the activity of the TGF-β signaling pathway [PDF]
The N6-methyladenosine (m6A) modification is prevalently found in mRNAs and lncRNAs in various eukaryotic organisms, playing a crucial role in biological processes.
Yuchen Shan+8 more
doaj +2 more sources