Results 21 to 30 of about 8,355 (219)

Non-rational Narain CFTs from codes over $F_4$ [PDF]

open access: yesHigh Energ. Phys. 2021, 16 (2021), 2021
We construct a map between a class of codes over $F_4$ and a family of non-rational Narain CFTs. This construction is complementary to a recently introduced relation between quantum stabilizer codes and a class of rational Narain theories. From the modular bootstrap point of view we formulate a polynomial ansatz for the partition function which reduces
arxiv   +1 more source

ANALYSIS OF FAST NEUTRON TRANSPORT IN CHLORIDE SALTS USING MONTE CARLO METHOD

open access: yesActa Polytechnica CTU Proceedings, 2020
The aim of this paper is to present results of fast neutron behavior analysis within the chloride salts environment using simulations based on Monte Carlo method (MCNP 6.2).
Ondřej Šťastný   +4 more
doaj   +1 more source

ADAR expression and copy number variation in patients with advanced gastric cancer

open access: yesBMC Gastroenterology, 2020
Background Gastric cancer (GC) is a world health problem and it is the third leading cause of cancer deaths worldwide. The current practice for prognosis assessment in GC is based on radiological and pathological criteria and they may not result in an ...
Javad Behroozi   +3 more
doaj   +1 more source

The A to I editing landscape in melanoma and its relation to clinical outcome

open access: yesRNA Biology, 2022
RNA editing refers to non-transient RNA modifications that occur after transcription and prior to translation by the ribosomes. RNA editing is more widespread in cancer cells than in non-transformed cells and is associated with tumorigenesis of various ...
Austeja Amweg   +11 more
doaj   +1 more source

ADAR RNA Modifications, the Epitranscriptome and Innate Immunity [PDF]

open access: yesTrends in Biochemical Sciences, 2021
Modified bases act as marks on cellular RNAs so that they can be distinguished from foreign RNAs, reducing innate immune responses to endogenous RNA. In humans, mutations giving reduced levels of one base modification, adenosine-to-inosine deamination, cause a viral infection mimic syndrome, a congenital encephalitis with aberrant interferon induction.
Quin, Jaclyn   +5 more
openaire   +4 more sources

Evaluation of the Interplay between the ADAR Editome and Immunotherapy in Melanoma [PDF]

open access: yesNon-Coding RNA, 2021
Background: RNA editing is a highly conserved posttranscriptional mechanism that contributes to transcriptome diversity. In mammals, it includes nucleobase deaminations that convert cytidine (C) into uridine (U) and adenosine (A) into inosine (I).
Steve Pascolo   +11 more
openaire   +6 more sources

Dynamic hyper-editing underlies temperature adaptation in Drosophila. [PDF]

open access: yesPLoS Genetics, 2017
In Drosophila, A-to-I editing is prevalent in the brain, and mutations in the editing enzyme ADAR correlate with specific behavioral defects. Here we demonstrate a role for ADAR in behavioral temperature adaptation in Drosophila.
Ilana Buchumenski   +6 more
doaj   +1 more source

Programmable RNA editing with endogenous ADAR enzymes – a feasible option for the treatment of inherited retinal disease?

open access: yesFrontiers in Molecular Neuroscience, 2023
RNA editing holds great promise for the therapeutic correction of pathogenic, single nucleotide variants (SNV) in the human transcriptome since it does not risk creating permanent off-targets edits in the genome and has the potential for innovative ...
Julia-Sophia Bellingrath   +5 more
doaj   +1 more source

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