Results 51 to 60 of about 42,221 (215)
Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site [PDF]
, 2002 RNA editing by members of the ADAR (adenosine deaminase that acts on RNA) enzyme family involves hydrolytic deamination of adenosine to inosine within the context of a double-stranded pre-mRNA substrate.
Collins, Cynthia H. +2 more
core +1 more source
Journal of Traumatic Stress, EarlyView.Abstract Cognitive dysfunction is a hallmark of posttraumatic stress disorder (PTSD). Although treatments effectively reduce core PTSD symptoms, limited research has examined whether associated cognitive impairments improve following treatment.
Zulkayda Mamat +2 more
wiley +1 more source
Molecular Genetics & Genomic Medicine, 2019 Background Dyschromatosis symmetrica hereditaria (DSH;OMIM: #127400) is a rare autosomal dominant skin disease of hyperpigmented and hypopigmented macules on the dorsal aspects of the feet and hands.
Peng Wang +4 more
doaj +1 more source
Link Prediction using Top-$k$ Shortest Distances
, 2017 In this paper, we apply an efficient top-$k$ shortest distance routing algorithm to the link prediction problem and test its efficacy. We compare the results with other base line and state-of-the-art methods as well as with the shortest path. Our results
Lebedev, Andrei +3 more
core +1 more source
People and Nature, EarlyView.Abstract The future of land use in the UK uplands is highly debated, with growing interest in increasing tree cover and other land use changes, alongside a desire to maintain traditional land use patterns and practices. Treescape expansion is likely to result in synergies and trade‐offs between different outcomes, so integrating stakeholder preferences
Melissa Minter +6 more
wiley +1 more source
Remote Sensing in Ecology and Conservation, EarlyView.Accurately estimating forest age is key to understanding how forests recover and evaluating restoration success. We developed a two‐step deep learning approach using historical greyscale aerial photographs to map forest age at fine spatial scales. By combining a pre‐trained model with localized fine‐tuning, our U‐Net + ResNet50 architecture achieved ...
Ying Ki Law +10 more
wiley +1 more source
Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs
Genome Biology, 2017 One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR family of enzymes.
Carl R. Walkley, Jin Billy Li
doaj +1 more source
In vivo RNA editing of point mutations via RNA-guided adenosine deaminases. [PDF]
, 2019 We present in vivo sequence-specific RNA base editing via adenosine deaminases acting on RNA (ADAR) enzymes with associated ADAR guide RNAs (adRNAs). To achieve this, we systematically engineered adRNAs to harness ADARs, and comprehensively evaluated the
Chen, Genghao +7 more
core +1 more source
Insect Science, EarlyView.Aphids pose a serious risk to horticultural crops. Current biocontrol strategies often fail due to the poor establishment of natural enemies when aphids are scarce. We evaluated the potential of two aphidophagous predators, Micromus variegatus and Scymnus interruptus, to be used as preventive biocontrol agents, released before aphid infestation.
Jesica Pérez‐Rodríguez +3 more
wiley +1 more source
ADAR mediates differential expression of polycistronic microRNAs [PDF]
Nucleic Acids Research, 2014 Adenosine deaminases acting on RNAs (ADARs) convert adenosine residues to inosines in primary microRNA (pri-miRNA) transcripts to alter the structural conformation of these precursors and the subsequent functions of the encoded microRNAs (miRNAs). Here we show that RNA editing by Drosophila ADAR modulates the expression of three co-transcribed miRNAs ...
Chawla, Geetanjali, Sokol, Nicholas S.
openaire +2 more sources