Results 51 to 60 of about 42,601 (251)

Stochastic Block Models with Multiple Continuous Attributes [PDF]

open access: yes, 2018
The stochastic block model (SBM) is a probabilistic model for community structure in networks. Typically, only the adjacency matrix is used to perform SBM parameter inference.
Bonacci, Thomas   +4 more
core   +3 more sources

Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections

open access: yesBMC Genomics, 2023
Background RNA editing is a process that increases transcriptome diversity, often through Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of adenosine to inosine.
Benjamin Wales-McGrath   +2 more
doaj   +1 more source

Adare Convent

open access: yes, 1937
A collection of folklore and local history stories from Adare Convent (school) (Adare, Co. Limerick), collected as part of the Schools' Folklore Scheme, 1937-1938 under the supervision of teacher An tSr. Mechtildes.
Adare Convent   +23 more
openaire   +1 more source

Monitoring Challenges and Approaches for P2P File-Sharing Systems [PDF]

open access: yes, 2006
Since the release of Napster in 1999, P2P file-sharing has enjoyed a dramatic rise in popularity. A 2000 study by Plonka on the University of Wisconsin campus network found that file-sharing accounted for a comparable volume of traffic to HTTP, while a ...
Hughes, D., Lee, K., Walkerdine, J.
core   +2 more sources

Inferring Person-to-person Proximity Using WiFi Signals [PDF]

open access: yes, 2016
Today's societies are enveloped in an ever-growing telecommunication infrastructure. This infrastructure offers important opportunities for sensing and recording a multitude of human behaviors.
Lehmann, Sune   +4 more
core   +2 more sources

Adar is essential for optimal presynaptic function [PDF]

open access: yesMolecular and Cellular Neuroscience, 2013
RNA editing is a powerful way to recode genetic information. Because it potentially affects RNA targets that are predominantly present in neurons, it is widely hypothesized to affect neuronal structure and physiology. Across phyla, loss of the enzyme responsible for RNA editing, Adar, leads to behavioral changes, impaired locomotion, neurodegeneration ...
Carolina, Maldonado   +4 more
openaire   +2 more sources

Unveiling RNA Editing by ADAR and APOBEC Protein Gene Families

open access: yesFrontiers in Bioscience-Landmark
RNA editing is a crucial post-transcriptional modification that alters the transcriptome and proteome and affects many cellular processes, including splicing, microRNA specificity, stability of RNA molecules, and protein structure.
Alexander Modestov   +2 more
doaj   +1 more source

ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity. [PDF]

open access: yes, 2016
It has been postulated that synaptic potentiation during waking is offset by a homoeostatic reduction in net synaptic strength during sleep. However, molecular mechanisms to support such a process are lacking. Here we demonstrate that deficiencies in the
Dickman, DK   +3 more
core  

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

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