Results 121 to 130 of about 7,998 (203)

Active Ebola Virus Replication and Heterogeneous Evolutionary Rates in EVD Survivors [PDF]

, 2018
Summary: Following cessation of continuous Ebola virus (EBOV) transmission within Western Africa, sporadic EBOV disease (EVD) cases continued to re-emerge beyond the viral incubation period.
Alfson, Arias, Baczko, Barnes, Bass, Bausch, Blackley, Calain, Cattaneo, Christie, Deen, Dejucq, Delwart, Diallo, Dudas, Duffy, George, Gire, Gupta, Gélinas, Iizasa, Jacobs, Kumar, Kuming, Ladner, Li, Martini, Martínez, Mate, Meyer, Meyer, Ni, Park, Pfaller, Pillai, Randall, Rice, Rodriguez, Rowe, Shabman, Simon-Loriere, Sissoko, Sissoko, Smits, Soka, Spengler, Suspène, Tapia, Tong, Uyeki, Varkey, Volchkova, Zahn   +52 more
core   +2 more sources

Movement Disorders Presenting in Childhood. [PDF]

, 2016
PURPOSE OF REVIEW: This article provides an overview of movement disorders that present in childhood. Key clinical features are discussed, and a brief guide to management strategies is provided.
Dale, RC, Kurian, MA
core   +1 more source

Meme kanserli hastalarda ADAR1 gen ifade değişikliklerinin adar1 aracılı RNA düzenlenmesi ile BRCA1 ifadesine etkisi

, 2023
Somatik mutasyonlar ve bağışıklık yanıtından kaçış, kanserin başlamasında ve ilerlemesinde rol oynayan iki temel faktördür. Artan sayıda ikinci nesil dizileme verileriyle birlikte, RNA mutasyonları olarak da adlandırılan transkriptomik modifikasyonlar, normal hücrelerin kötü huylu tümöre geçişini yönlendiren ve aynı zamanda bağışıklık yanıtından kaçmak
openaire   +1 more source

ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway

Cancer Management and Research, 2019
Han Xiao, Qian Cheng, Xinyu Wu, Yishu Tang, Jing Liu, Xin Li Department of Hematology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of ChinaCorrespondence: Xin Li; Jing LiuDepartment of Hematology, The ...
Xiao H, Cheng Q, Wu X, Tang Y, Liu J, Li X   +5 more
doaj  

Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line

eLife, 2017
ADAR1 isoforms are adenosine deaminases that edit and destabilize double-stranded RNA reducing its immunostimulatory activities. Mutation of ADAR1 leads to a severe neurodevelopmental and inflammatory disease of children, Aicardi-Goutiéres syndrome.
Yize Li, Shuvojit Banerjee, Stephen A Goldstein, Beihua Dong, Christina Gaughan, Sneha Rath, Jesse Donovan, Alexei Korennykh, Robert H Silverman, Susan R Weiss   +9 more
doaj   +1 more source

ADAR1 affects HCV infection by modulating innate immune response

Antiviral Research, 2018
The hepatitis C virus (HCV) is a globally prevalent infectious pathogen. As many as 80% of people infected with HCV do not control the virus and develop a chronic infection. Response to interferon (IFN) therapy is widely variable in chronic HCV infected patients, suggesting that HCV has evolved mechanisms to suppress and evade innate immunity ...
Maria Pujantell, Sandra Franco, Iván Galván-Femenía, Roger Badia, Marc Castellví, Edurne Garcia-Vidal, Bonaventura Clotet, Rafael de Cid, Cristina Tural, Miguel A. Martínez, Eva Riveira-Muñoz, José A. Esté, Ester Ballana   +12 more
openaire   +3 more sources

REPAIR - new tool for RNA editing with Cas13 [PDF]

, 2018
Istraživači su nedavno razvili alat REPAIR koji se sastoji od spojene katalitičke domene deaminaze ADAR i katalitički mrtvog Cas13b, iz obitelji proteina Cas13.
Majsec, Petra
core   +2 more sources

ADAR1 Promotes Myogenic Proliferation and Differentiation of Goat Skeletal Muscle Satellite Cells

Cells
As one of the most important economic traits for domestic animal husbandry, skeletal muscle is regulated by an intricate molecular network. Adenosine deaminase acting on RNA (ADAR1) involves various physiological processes and diseases, such as innate ...
Zihao Zhao, Miao Xiao, Xiaoli Xu, Meijun Song, Dinghui Dai, Siyuan Zhan, Jiaxue Cao, Jiazhong Guo, Tao Zhong, Linjie Wang, Li Li, Hongping Zhang   +11 more
doaj   +1 more source

Single molecule pull down of double strand RNA binding proteins [PDF]

, 2015
RNA molecules are transcribed as single stranded naturally, but with most of them forming in to structures composed of duplex regions, loop, bulge or mismatches. RNAs with double stranded regions, or known as double-strand RNAs (dsRNAs).
Wang, Xinlei
core  

The role of RNA editing in cancer development and metabolic disorders [PDF]

, 2018
Kung, Che-Pei, Maggi, Leonard B, Jr., Weber, Jason D   +2 more
core   +2 more sources