Results 21 to 30 of about 731,675 (357)

Stability of Diluted Adenosine Solutions in Polyolefin Infusion Bags [PDF]

, 2013
Background Intravenous or intracoronary adenosine is used in the cardiac catherization lab to achieve maximal coronary blood flow and determine fractional flow reserve.
Almagambetova, Elise, Blais, Danielle M., Hutchinson, David, Zhao, Fang   +3 more
core   +2 more sources

Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug? [PDF]

The Journal of Pharmacology and Experimental Therapeutics, 2019
Adenosine receptors (ARs) represent key drug targets in many human pathologies, including cardiovascular, neurologic, and inflammatory diseases. To overcome the very rapid metabolization of adenosine, metabolically stable AR agonists and antagonists were developed.
Rouquette, Marie, Lepetre-Mouelhi, Sinda, Dufrançais, Ophélie, Yang, Xue, Mougin, Julie, Pieters, Grégory, Garcia-Argote, Sébastien, Ijzerman, Adriaan, Couvreur, Patrick, Rouquette, Marie   +9 more
openaire   +4 more sources

Computerized Modeling of Adenosine Triphosphate, Adenosine Triarsenate and Adenosine Trivanadate [PDF]

Molecules, 2012
Computerized molecular models of adenosine triphosphate, adenosine tri-arsenate and adenosine trivanadate have been generated using the molecular mechanics technique. The analysis of structural parameters indicated that, at least theoretically, adenosine triarsenate is a realistic candidate for replacement of adenosine triphosphate in biochemical ...
Nascimento, Valter A., Melnikov, Petr, Consolo, Lourdes Z. Z.   +2 more
openaire   +3 more sources

Biosensor measurement of purine release from cerebellar cultures and slices [PDF]

, 2010
We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Dale, Nicholas, Eason, Robert, Wall, Mark J.   +2 more
core   +3 more sources

Treatment With Methotrexate Associated With Lipid Core Nanoparticles Prevents Aortic Dilation in a Murine Model of Marfan Syndrome

Frontiers in Cardiovascular Medicine, 2022
In Marfan syndrome (MFS), dilation, dissection, and rupture of the aorta occur. Inflammation can be involved in the pathogenicity of aortic defects and can thus be a therapeutic target for MFS.
Maria Carolina Guido, Natalia de Menezes Lopes, Camila Inagaki Albuquerque, Elaine Rufo Tavares, Leonardo Jensen, Priscila de Oliveira Carvalho, Thauany Martins Tavoni, Ricardo Ribeiro Dias, Lygia da Veiga Pereira, Francisco Rafael Martins Laurindo, Raul Cavalcante Maranhão   +10 more
doaj   +1 more source

Caffeine and Adenosine [PDF]

Journal of Alzheimer's Disease, 2010
Caffeine causes most of its biological effects via antagonizing all types of adenosine receptors (ARs): A1, A2A, A3, and A2B and, as does adenosine, exerts effects on neurons and glial cells of all brain areas. In consequence, caffeine, when acting as an AR antagonist, is doing the opposite of activation of adenosine receptors due to removal of ...
Ribeiro, Joaquim A., Sebastião, Ana M
openaire   +3 more sources

The dynamics of single spike-evoked adenosine release in the cerebellum [PDF]

, 2010
The purine adenosine is a potent neuromodulator in the brain, with roles in a number of diverse physiological and pathological processes. Modulators such as adenosine are difficult to study as once released they have a diffuse action (which can affect ...
Beierlein, Bellamy, Boison, Bordey, Boris P. Klyuch, Brasnjo, Clark, Craig, Dale, Dale, Dale, Daniel, Delaney, Edwards, Fredholm, Fredholm, Isope, Jo, Kimura, Li, Llaudet, Llaudet, Magnus J. E. Richardson, Mark J. Wall, Martín, Mitchell, Mitterdorfer, Nedergaard, Neher, Nicholas Dale, Pearson, Pearson, Piet, Richardson, Rossi, Sabatini, Sweeney, Tsodyks, Wall, Wall, Wall, Wong   +41 more
core   +2 more sources

Comparison between adenosine triphosphate bioluminescence and aerobic colony count to assess surface sanitation in the hospital environment [PDF]

, 2018
Background: Adenosine triphosphate bioluminescence produced by the firefly luciferase has been successfully introduced to verify cleaning procedures in the food industry according to the Hazard Analysis Critical Control Point program.
Alagna E., Aprea L., Bonanno V., Cannova L., Firenze A., Piazza D., Provenzano S., Raia D. D., Santangelo O. E.   +8 more
core   +1 more source

Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5′-Nucleotidase (CD73)

Frontiers in Pharmacology, 2020
The airways are a target tissue of type I allergies and atopy is the main etiological factor of bronchial asthma. A predisposition to allergy and individual response to allergens are dependent upon environmental and host factors.
Elisabetta Caiazzo, Ida Cerqua, Maria Antonietta Riemma, Roberta Turiello, Roberta Turiello, Armando Ialenti, Jurgen Schrader, Giuseppe Fiume, Carmen Caiazza, Fiorentina Roviezzo, Silvana Morello, Carla Cicala   +11 more
doaj   +1 more source

Adenosine Receptors Profile in Fibromuscular Dysplasia

Biomedicines, 2022
Fibromuscular dysplasia (FMD) is a non-inflammatory vascular disease that is characterized by unexplained systemic hypertension occurring in young people, associated with arterial stenosis, aneurysm rupture, intracranial/renal infarction, and stroke ...
Claire Guiol, Sarah El Harake, Julien Fromonot, Mohamed Chefrour, Marguerite Gastaldi, Yassine Alibouch, Maxime Doublier, Pierre Deharo, Gabrielle Sarlon, Marion Marlinge, Nathalie Lalevee, Régis Guieu, François Silhol   +12 more
doaj   +1 more source