Results 241 to 250 of about 761,976 (296)
BMEMat, EarlyView.This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu +9 more
wiley +1 more source
Programmable three‐state nanoreactor for spatiotemporally controlled tumor therapy
BMEMat, EarlyView.The OMVs are shielded with a biocompatible Da–Ca shell, which prolongs its circulation period and promotes intratumoral accumulation. Importantly, the biocompatible Da–Ca shell can be controllably disintegrated in tumor microenvironment by using laser irradiation, generating in situ hyperthermia and releasing Ca2+.
Guihong Lu +12 more
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Adenosine and adenosine receptors in colorectal cancer
International Immunopharmacology, 2020CD39 (nucleoside triphosphate diphosphohydrolase) and Ecto-5-nucleotidase (CD73) have been recognized as important factors mediating various pathological and physiological responses in the tumor microenvironment. Elevated expression of CD73 and CD39 is correlated with the over-production of adenosine in the tumor region.
Farnaz, Hajizadeh +7 more
openaire +2 more sources
Adenosine and Adenosine Receptors
American Journal of Respiratory Cell and Molecular Biology, 1990In the last decade, there has been renewed interest in extracellular signaling by adenosine and adenine nucleotides. The potent cardiovascular effects of these agents were originally described by Drury and Szent-Gy6rgyi in 1929 (1). This report was followed by a flurry of interest in the use of adenosine as an antihypertensive agent, which subsided ...
openaire +3 more sources
Trends in Pharmacological Sciences, 1993
The numerous and widespread effects of adenosine provide both an opportunity for the development of novel therapeutic agents acting via adenosine receptors and the challenge of achieving selectivity of action. The feasibility of achieving selectivity is enhanced if receptor subtypes can be identified.
M G, Collis, S M, Hourani
openaire +2 more sources
The numerous and widespread effects of adenosine provide both an opportunity for the development of novel therapeutic agents acting via adenosine receptors and the challenge of achieving selectivity of action. The feasibility of achieving selectivity is enhanced if receptor subtypes can be identified.
M G, Collis, S M, Hourani
openaire +2 more sources
Adenosine receptors and their modulators
Pharmaceutica Acta Helvetiae, 1993The identification and characterization of adenosine receptors and the development of potent, receptor subtype-selective agonists and antagonists has been an active area of research for the past 20 years. Major recent advances in the field have been the cloning of several adenosine receptor subtypes of different species, including the discovery of a ...
C E, Müller, T, Scior
openaire +2 more sources
Adenosine receptors and their ligands
Naunyn-Schmiedeberg's Archives of Pharmacology, 2000The regulatory actions of adenosine are mediated via four subtypes of G protein-coupled receptors distinguished as A1, A2A, A2B and A3 receptors. Their presence on basically every cell makes them an interesting target for the pharmacological intervention in many pathophysiological situations.
openaire +2 more sources
2002
Abstract Adenosine is not a neurotransmitter but rather a paracrine neuromodulator. This obviously does not mean that adenosine is not biologically important—it just means that we must think differently about its role compared to, for example, dopamine or noradrenaline.
openaire +2 more sources
Abstract Adenosine is not a neurotransmitter but rather a paracrine neuromodulator. This obviously does not mean that adenosine is not biologically important—it just means that we must think differently about its role compared to, for example, dopamine or noradrenaline.
openaire +2 more sources
Adenosine Receptors and Inflammation
2009Extracellular adenosine is produced in a coordinated manner from cells following cellular challenge or tissue injury. Once produced, it serves as an autocrine- and paracrine-signaling molecule through its interactions with seven-membrane-spanning G-protein-coupled adenosine receptors.
Michael R, Blackburn +3 more
openaire +2 more sources