Results 251 to 260 of about 271,223 (294)

Selective adenosine A2A receptor antagonists

Il Farmaco, 2001
In the early 1990s it became clear that the A2A adenosine receptor had characteristics that made it distinct from the other A1, A2B and A3 adenosine receptors. Great progress has been made with the discovery of selective A2A receptor antagonists. A variety of synthetic substitutions on the xanthine moiety led the chemists of Kyowa-Hakko to discover ...
BARALDI, Pier Giovanni, MONOPOLI A, CACCIARI, Barbara, BARALDI PG   +3 more
openaire   +2 more sources

Adenosine Receptor Neurobiology: Overview

2014
Adenosine is a naturally occurring nucleoside that is distributed ubiquitously throughout the body as a metabolic intermediary. In the brain, adenosine functions as an important upstream neuromodulator of a broad spectrum of neurotransmitters, receptors, and signaling pathways.
Jiang-Fan, Chen, Chien-fei, Lee, Yijuang, Chern   +2 more
openaire   +2 more sources

Adenosine Receptors on Human Lymphocytes

1986
Evidence is accumulating that adenosine functions as an important immunoregulatory autacoid (1,2). Adenosine inhibits the mitotic response of human lymphocytes (3,4), lymphocyte-mediated cytolysis (5), superoxide anion generation by neutrophils (6), platelet aggregation (7) and mediator release from human basophils (8-10). The nucleoside has been shown
MARONE, GIANNI, R. PETRACCA, S. VIGORITA, M. PLAUT   +3 more
openaire   +4 more sources

Adenosine receptors

Neuropharmacology, 1995
T M, Palmer, G L, Stiles
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Adenosine and ATP Receptors

2007
Adenosine and ATP, via P1 and P2 receptors respectively, can modulate pain transmission under physiological, inflammatory, and neuropathic pain conditions. Such influences reflect peripheral and central actions and effects on neurons as well as other cell types.
openaire   +2 more sources

Adenosine A2B Receptors

Pharmacological Reviews, 1997
I, Feoktistov, I, Biaggioni
openaire   +2 more sources

A3 Adenosine Receptor Antagonists

Mini-Reviews in Medicinal Chemistry, 2001
During the past years a number of potent and selective antagonists for the human A(3) adenosine receptor (AR) have been developed, including tricyclic compounds, such as triazoloquinazoline, pyrazolo-triazolopyridine, imidazopurinone, triazoloquinoxaline and pyrazoloquinoline derivatives.
openaire   +2 more sources

Adenosine Receptors

Annals of the New York Academy of Sciences, 1990
openaire   +3 more sources

Adenosine and adenosine receptors

Trends in Pharmacological Sciences, 1991
openaire   +1 more source

Adenosine and adenosine receptors

Biochimie, 1992
openaire   +1 more source