Results 81 to 90 of about 803,750 (296)

ATP‐Mediated Bidirectional Communication Between Natural and Artificial Cells for Controlled Bioreactions

open access: yesAdvanced Functional Materials, EarlyView.
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte   +6 more
wiley   +1 more source

Adenosine Receptors and Wound Healing, Revised

open access: yesThe Scientific World Journal, 2006
Recent studies have demonstrated that application of topical adenosine A2A receptor agonists promotes more rapid wound closure and clinical studies are currently underway to determine the utility of topical A2A adenosine receptor agonists in the therapy ...
Bruce M. Cronstein
doaj   +1 more source

Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Signaling of Gs protein-coupled receptors (GsPCRs) is accomplished by stimulation of adenylyl cyclase, causing an increase of the intracellular cAMP concentration, activation of the intracellular cAMP effectors protein kinase A (PKA) and
Thomas Pleli   +11 more
doaj   +1 more source

Endothelial and Neuronal Nitric Oxide Activate Distinct Pathways on Sympathetic Neurotransmission in Rat Tail and Mesenteric Arteries. [PDF]

open access: yesPLoS ONE, 2015
Nitric oxide (NO) seems to contribute to vascular homeostasis regulating neurotransmission. This work aimed at assessing the influence of NO from different sources and respective intracellular pathways on sympathetic neurotransmission, in two vascular ...
Joana Beatriz Sousa   +5 more
doaj   +1 more source

Stimulation of glia reveals modulation of mammalian spinal motor networks by adenosine [PDF]

open access: yes, 2015
This work was funded by the Wellcome Trust Institutional Strategic Support Fund for University of St. Andrews.Despite considerable evidence that glia can release modulators to influence the excitability of neighbouring neurons, the importance of ...
Miles, Gareth B.   +6 more
core   +2 more sources

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

open access: yesAdvanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li   +10 more
wiley   +1 more source

Purinergic Receptors in Adipose Tissue As Potential Targets in Metabolic Disorders

open access: yesFrontiers in Pharmacology, 2017
Extracellular nucleosides and nucleotides, such as adenosine and adenosine triphosphate (ATP), are involved in many physiological and pathological processes in adipose tissue (AT).
Marco Tozzi, Ivana Novak
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

open access: yesAdvanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Unlocking the adenosine receptor mechanism of the tumour immune microenvironment

open access: yesFrontiers in Immunology
The suppressive tumour microenvironment significantly hinders the efficacy of immunotherapy in treating solid tumors. In this context, stromal cells, such as tumour-associated fibroblasts, undergo changes that include an increase in the number and ...
Yecheng Han   +4 more
doaj   +1 more source

Regulation of inflammation by adenosine

open access: yesFrontiers in Immunology, 2013
Adenosine, a purine nucleoside generated by the dephorphorylation of adenine nucleotides, is a potent endogenous physiologic and pharmacologic regulator of many functions.
Bruce Neil Cronstein   +2 more
doaj   +1 more source

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