Results 71 to 80 of about 156,709 (208)

Resetting intrinsic purinergic modulation of neural activity: an associative mechanism? [PDF]

, 2002
The purines, ATP and adenosine, control the rundown and termination of swimming in the Xenopus embryo. This intrinsic purinergic modulation, unavoidably present during every swimming episode, could lead to stereotyped inflexible behavior and consequently
Dale, Nicholas, Nicholas Dale
core   +1 more source

Regulation of inflammation by adenosine

Frontiers in Immunology, 2013
Adenosine, a purine nucleoside generated by the dephorphorylation of adenine nucleotides, is a potent endogenous physiologic and pharmacologic regulator of many functions.
Bruce Neil Cronstein, Bruce Neil Cronstein, György eHaskó   +2 more
doaj   +1 more source

ALTERED EXPRESSION AND FUNCTIONALITY OF A2A ADENOSINE RECEPTORS IN HUNTINGTON’S DISEASE AND OTHER POLYGLUTAMINE DISORDERS

, 2009
Several studies have suggested the possible involvement of A2A adenosine receptors in the pathogenesis of neuronal disorders, including Huntington’s disease.
Vincenzi, Fabrizio
core  

G Protein-Coupled Receptors: Chemical and Structural Insights for Drug Discovery [PDF]

Records of Pharmaceutical & Biomedical Sciences
G-protein coupled receptors (GPCRs) are very popular as integral membrane protein receptors which are used by cells to transfer the extracellular signals into intracellular responses.
Manar Nagy, Safaa Kishk, Khaled Darwish, Samia Mostafa, Ismail Salama   +4 more
doaj   +1 more source

Stimulation of glia reveals modulation of mammalian spinal motor networks by adenosine

, 2015
This work was funded by the Wellcome Trust Institutional Strategic Support Fund for University of St. Andrews.Despite considerable evidence that glia can release modulators to influence the excitability of neighbouring neurons, the importance of ...
Miles, Gareth B., David Acton, Acton David, Miles Gareth B., Acton, David, Gareth B Miles   +5 more
core   +1 more source

ADENOSINE RECEPTORS IN RESPIRATORY DISORDERS AS CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND MALIGNANT PLEURAL MESOTHELIOMA

, 2012
Adenosine is a purine nucleoside that is commonly expressed in the body and involved in a wide range of physiological processes. The effects of adenosine are mediated through specific G-protein coupled cell surface receptors, named A1, A2A, A2B and A3 ...
Targa, Martina
core  

The role of the large conductance Ca2+-activated K+ channel in adenosine receptor-mediated cytoprotection

, 2009
The rat embryonic cardiomyoblast-derived H9c2 cell line is increasingly used for studies into cardioprotection, as these cells display similar properties to primary cardiomyocytes.
Fretwell, Laurice V, Fretwell, LV
core  

Purines as potential morphogens during embryonic development [PDF]

, 2012
Components of purinergic signalling are expressed in the early embryo raising the possibility that ATP, ADP and adenosine may contribute to the mechanisms of embryonic development.
Dale, Nicholas, Masse, Karine, Karine Massé, Nicholas Dale   +3 more
core   +1 more source

NEW INSIGHTS AND POSSIBLE THERAPEUTIC IMPLICATIONS OF ADENOSINE ANALOGS AND PULSED ELECTROMAGNETIC FIELDS (PEMFs) IN OSTEOARTICULAR PATHOLOGIES

, 2009
Objective: The aim of this study was to characterize adenosine receptors in synovial fibroblasts (SFs) and to investigate the potential link between adenosine pathway and pulsed electromagnetic fields (PEMFs).
Masieri, Federica Francesca
core  

Heteromerización de receptores de adenosina A2A, dopamina D2 y cannabinoides CB1. Implicaciones farmacológicas y funcionales. [PDF]

, 2007
[spa] La visión de los receptores acoplados a proteína G ha evolucionado en los últimos años. Clásicamente se consideraban unidades individuales capaces de producir una señal intracelular; actualmente, está aceptado que estas proteínas de membrana pueden
Carriba Domínguez, Paulina
core