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Serotype Chimeric Human Adenoviruses for Cancer GeneTherapy [PDF]

open access: yesViruses, 2010
Cancer gene therapy consists of numerous approaches where the common denominator is utilization of vectors for achieving therapeutic effect. A particularly potent embodiment of the approach is virotherapy, in which the replication potential of an ...
Akseli Hemminki, Tuuli Ranki
doaj   +4 more sources

The seroprevalence of adenoviruses since 20001 [PDF]

open access: yesEmerging Microbes and Infections
Human adenoviruses (Ad) are increasingly used as vaccine vectors, especially after Ad5, Ad26, and ChAdY25 (ChAdOx1) were employed as vectors for SARS-CoV-2 vaccines. So far, more than 116 adenovirus genotypes have been identified, divided into 7 species (
Lingling Hong   +7 more
doaj   +2 more sources

Anti-Viral Drugs for Human Adenoviruses

open access: yesPharmaceuticals, 2010
There are many stages in the development of a new drug for viral infection and such processes are even further complicated for adenovirus by the fact that there are at least 51 serotypes, forming six distinct groups (A–F), with different degree of ...
Chor Wing Sing, Mary Miu Yee Waye
doaj   +2 more sources

Evolution of Human Adenoviruses, a Double-Stranded DNA Viral Pathogen Documented Through Genomics and Bioinformatics and Viewed Through a Web Resource Database [PDF]

open access: yesViruses
Human adenoviruses (HAdVs) remain prominent global human pathogens, particularly in dense, crowded populations. The advent of genomic and bioinformatic tools allows for high-resolution means to identify, characterize, and understand these pathogens ...
Katayoon Dadkhah   +4 more
doaj   +2 more sources

A brief review on the molecular biology of human adenoviruses

open access: yesBaghdad Journal of Biochemistry and Applied Biological Sciences, 2022
Human adenoviruses infection causes diseases worldwide in all age groups and genders, which is associated with a wide range of diseases affecting the gastrointestinal tract, respiratory tract, urinary tract, and the eye, but they are often isolated from ...
Buhari Suraka, Umar Usman, Aminu Tijjani
doaj   +1 more source

Almost famous: Human adenoviruses (and what they have taught us about cancer)

open access: yesTumour Virus Research, 2021
Papillomaviruses, polyomaviruses and adenoviruses are collectively categorized as the small DNA tumour viruses. Notably, human adenoviruses were the first human viruses demonstrated to be able to cause cancer, albeit in non-human animal models.
Tanner M. Tessier   +5 more
doaj   +1 more source

Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates. [PDF]

open access: yesPLoS Pathogens, 2009
Adenoviruses are important human pathogens that have been developed as vectors for gene therapies and genetic vaccines. Previous studies indicated that human infections with adenoviruses are self-limiting in immunocompetent hosts with evidence of some ...
Soumitra Roy   +11 more
doaj   +1 more source

Human adenovirus infections in pediatric population - An update on clinico–pathologic correlation

open access: yesBiomedical Journal, 2022
Human adenoviruses can cause infections at any age but most commonly in pediatric population, especially in young children and infants. By the time of 10 years old, most children have had at least one episode of adenovirus infection.
Wun-Ju Shieh
doaj   +1 more source

Simian adenoviruses: Molecular and serological survey in monkeys and humans in Thailand

open access: yesOne Health, 2022
Simian adenoviruses are in the genus Mastadenovirus of the family Adenoviridae. This family is composed of non-enveloped, double-stranded DNA viruses that infect a wide range of animals.
Nathamon Kosoltanapiwat   +8 more
doaj   +1 more source

Molecular evolution of human adenoviruses [PDF]

open access: yesScientific Reports, 2013
Scientific Reports | 3 ...
Robinson, Christopher   +11 more
openaire   +3 more sources

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