Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size. [PDF]
González Bullón D +4 more
europepmc +1 more source
Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin. [PDF]
Espinosa-Vinals CA +7 more
europepmc +1 more source
Bordetella bronchiseptica, a respiratory pathogen capable of infecting various mammals, including humans, is associated with chronic infections. B.
Sabrina Laura Mugni +4 more
doaj +1 more source
Adenylate cyclase toxin from Bordetella pertussis
E L Hewlett +4 more
openaire +1 more source
Susceptibility of primary human airway epithelial cells to Bordetella pertussis adenylate cyclase toxin in two- and three-dimensional culture conditions. [PDF]
Bianchi M +4 more
europepmc +1 more source
cAMP up-regulates IL-4 and IL-5 production from activated CD4+ T cells while decreasing IL-2 release and NF-AT induction [PDF]
Seven days after activation with concanavalin A and irradiated spleen cells, murine CD4+ T cells were re-stimulated with lonomycin and phorbol 12-myristate 13-acetate (PMA). IL-2 and IL-4 were determined in the supernatant.
Arrighi, Jean-François +5 more
core
ATP depletion in anthrax edema toxin pathogenesis.
Anthrax lethal toxin (LT) and edema toxin (ET) are two of the major virulence factors of Bacillus anthracis, the causative pathogen of anthrax disease. While the roles of LT in anthrax pathogenesis have been extensively studied, the pathogenic mechanism ...
Jie Liu +7 more
doaj +1 more source
Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin. [PDF]
Angely C +6 more
europepmc +1 more source
Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines. [PDF]
Altmann, DM +10 more
core +1 more source

