Results 101 to 110 of about 175,144 (193)

Prokaryotic adenylate cyclase toxin stimulates anterior pituitary cells in culture

, 1986
Bordetella pertussis synthesizes a variety of virulence factors including a calmodulin-dependent adenylate cyclase (AC) toxin. Treatment of anterior pituitary cells with this AC toxin resulted in an increase in cellular cAMP levels that was associated ...
D. N. Orth, A. D. Rogol, E. L. Hewlett, M. J. Cronin, M. O. Thorner, A. A. Weiss, T. Yasumoto, W. S. Evans, W. E. Nicholson   +8 more
core   +1 more source

The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity. [PDF]

J Biol Chem, 2023
Chen G, Wang H, Bumba L, Masin J, Sebo P, Li H.   +5 more
europepmc   +1 more source

Adenylate cyclase toxin of Bordetella parapertussis disrupts the epithelial barrier granting the bacterial access to the intracellular space of epithelial cells. [PDF]

PLoS One, 2023
Gorgojo JP, Carrica MDC, Baroli CM, Valdez HA, Alvarez Hayes J, Rodriguez ME.   +5 more
europepmc   +1 more source

Regulation of Neuronal Adenylate Cyclase Activity [PDF]

, 1987
Neuronal adenylate cyclase is responsive to a variety of neurotransmitters which stimulate or inhibit that enzyme. Recent studies concerning the molecular identification of the adenylate cyclase components have elucidated the molecular mechanism linking ...
八田, 愼一
core   +1 more source

The Draft Genome Sequence of the Yersinia entomophaga Entomopathogenic Type Strain MH96T

Toxins, 2016
Here we report the draft genome of Yersinia entomophaga type strain MH96T. The genome shows 93.8% nucleotide sequence identity to that of Yersinia nurmii type strain APN3a-cT, and comprises a single chromosome of approximately 4,275,531 bp.
Mark R. H. Hurst, Amy Beattie, Eric Altermann, Roger M. Moraga, Lincoln A. Harper, Joanne Calder, Aurelie Laugraud   +6 more
doaj   +1 more source

Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin. [PDF]

Cell Rep, 2022
Goldsmith JA, DiVenere AM, Maynard JA, McLellan JS.   +3 more
europepmc   +1 more source

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis. [PDF]

mBio, 2022
DiVenere AM, Amengor D, Silva RP, Goldsmith JA, McLellan JS, Maynard JA.   +5 more
europepmc   +1 more source

Cloning and expression of the calmodulin-sensitive Bacillus anthracis adenylate cyclase in Escherichia coli

, 1988
International audienceThe adenylate cyclase gene of Bacillus anthracis, encoding the edema factor, a component of anthrax toxin, has been cloned and expressed in Escherichia coli.
Labruyère, Elisabeth, Ullmann, Agnes, Glaser, Philippe, Danchin, Antoine, Mock, Michèle   +4 more
core   +1 more source

Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis. [PDF]

Int J Mol Sci, 2021
Holubova J, Juhasz A, Masin J, Stanek O, Jurnecka D, Osickova A, Sebo P, Osicka R.   +7 more
europepmc   +1 more source

Tannin inhibits adenylate cyclase in airway epithelial cells

, 1995
Tannin, isolated from cotton bracts extract and implicated in the pathogenesis of byssinosis, inhibits adenosine 3',5'-cyclic monophosphate (cAMP) production and Cl- secretion in bovine airway epithelial cells in part by inhibiting adrenergic receptor ...
M. M. Cloutier, L. Guernsey
core   +1 more source