Results 81 to 90 of about 175,144 (193)
Conformation of the adenylate cyclase toxin of Bordetella pertussis.
, 2021 This work is focused on the RTX (Repeats in ToXin) domains structure of selected RTX toxins and its impact on secretion and protein folding. The structural analysis included RTX domains of ApxI (Actinobacillus pleuropneumoniae-RTX-toxin I) from ...
Motlová, Lucia
core
Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]
, 2013 Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
Barth, Holger +24 more
core +2 more sources
Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3
eLife, 2015 Integrins are heterodimeric cell surface adhesion and signaling receptors that are essential for metazoan existence. Some integrins contain an I-domain that is a major ligand binding site.
Radim Osicka +5 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.GPR183/EBI2 links oxysterol metabolism with immune‐cell positioning and macrophage function in tuberculosis. The 7α,25‐OHC‐GPR183 axis regulates macrophage trafficking, autophagy and type I interferon responses. GPR183 represents a potential immunometabolic target for host‐directed therapy against tuberculosis..
Junfei Wang +4 more
wiley +1 more source
Toxins, 2017 Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Valérie Bouchez +6 more
doaj +1 more source
Stimulation of Intestinal Adenylate Cyclase by Cholera Toxin in Malnourished Rats
Experimental Biology and Medicine, 1985 The stimulation of intestinal adenylate cyclase by cholera toxin (CT) was studied in normal and malnourished rats 4 to 24 hr after a 30-min incubation of intestinal loops with the toxin. Whereas in control rats the enzyme activity returned to basal levels after 12 hr of incubation, in malnourished rats the activity of the enzyme remained significantly ...
I, Pérez-Schael, J, Flores
openaire +2 more sources
Bile acid metabolism and signaling in human and animal health: A One Health perspective
iMetaOmics, Volume 3, Issue 3, September 2026.Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Neurological disorders (NDs) are characterized by substantial loss of specific neurons, with Alzheimer's and Parkinson's diseases being the most frequent NDs and nearly 99% of all “foreign substances” are prohibited from entering the brain by the blood‐brain barrier (BBB) and the blood‐cerebrospinal fluid barrier (CFB).
Nnamdi Ikemefuna Okafor +3 more
wiley +1 more source
Conformation of the adenylate cyclase toxin of Bordetella pertussis.
, 2023 This work is focused on the RTX (Repeats in ToXin) domains structure of selected RTX toxins and its impact on secretion and protein folding. The structural analysis included RTX domains of ApxI (Actinobacillus pleuropneumoniae-RTX-toxin I) from ...
Motlová, Lucia
core
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.First report of Bordetella bronchiseptica in the reproductive tract of Brazilian mares. Uterine lavage samples from mares with endometritis and infertility were positive by culture, PCR (237 bp flaA), sequencing and phylogenetic analysis. Isolates showed multidrug resistance, emphasizing the relevance of this pathogen in equine reproductive disorders ...
Samira Salim Mello Gallo +5 more
wiley +1 more source