Results 121 to 130 of about 83,442 (296)
Expression of adenylyl cyclase isoforms in neutrophils
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2003 In the present study, we have identified the expression of adenylyl cyclase (AC) isoforms in rat neutrophils according to the mRNA analysis and the distinct mode of regulation of isoform activity. Agarose gel electrophoresis of reverse transcription-polymerase chain reaction (RT-PCR)-amplified products resulted in a single band of the expected size for
Ling-Chu Chang +3 more
openaire +3 more sources
Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review
Journal of Periodontal Research, EarlyView.Untargeted salivary proteomics identified promising biological molecules consistently over‐ or under‐expressed in periodontitis patients compared to periodontally healthy subjects, but further targeted approaches are required for their validation. ABSTRACT Aim Salivary content is regarded as a powerful diagnostic window for oral and systemic diseases ...
Matteo Corana +7 more
wiley +1 more source
An investigation of the response of a model class IIIA Adenyly Cyclase to carbon dioxide [PDF]
, 2009 Adenylyl cyclase catalyses the conversion of adenosine triphosphate into 3’,5'-cyclic adenosine monophosphate and pyrophosphate. Adenylyl cyclases are grouped into six distinct Classes based on amino acid sequence similarity.
Holliday, Phillip
core
Co-Localization of p-CREB and p-NR1 in Spinothalamic Neurons in a Chronic Muscle Pain Model [PDF]
, 2007 Activation of the cAMP pathway is an important mediator of chronic muscle pain. This study examined phosphorylation of the transcription factor cAMP-response-element-binding protein (p-CREB) and the NR1 subunit of the NMDA receptor (p-NR1) in the spinal ...
Bement, Marie K. Hoeger +1 more
core +2 more sources
Soluble adenylyl cyclase in health and disease
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2014 The second messenger cAMP is integral for many physiological processes. Soluble adenylyl cyclase (sAC) was recently identified as a widely expressed intracellular source of cAMP in mammalian cells. sAC is evolutionary, structurally, and biochemically distinct from the G-protein-responsive transmembranous adenylyl cyclases (tmAC).
Dimirela Meili +2 more
openaire +2 more sources
PLoS Neglected Tropical Diseases, 2010 BackgroundTrichomonas vaginalis has an unusually large genome (approximately 160 Mb) encoding approximately 60,000 proteins. With the goal of beginning to understand why some Trichomonas genes are present in so many copies, we characterized here a family
Jike Cui +3 more
doaj +1 more source
On the roles of Mg in the activation of G proteins [PDF]
, 2010 In this review, we highlight the evolution of our knowledge about the way Mg2+ participates in the activation of heterotrimeric G proteins, beginning with its requirement in hormonal stimulation of fat cell adenylyl cyclase (1969) and ending with ...
Birnbaumer, Lutz, Zurita, Adolfo Ramón
core +2 more sources
The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms
eLife, 2017 Adenylyl cyclases (ACs) generate cAMP, a second messenger of utmost importance that regulates a vast array of biological processes in all kingdoms of life.
Wenbao Hu +12 more
doaj +1 more source
Differential Coupling of Muscarinic m2 and m3 Receptors to Adenylyl Cyclases V/VI in Smooth Muscle
Journal of Biological Chemistry, 1997 Muscarinic m2 and m4 receptors couple preferentially to inhibition of adenylyl cyclase, whereas m1, m3, and m5 receptors couple preferentially to activation of phospholipase C-β and in some cells to stimulation of cAMP.
K. Murthy, G. Makhlouf
semanticscholar +1 more source
Old player, new roles: defining the role of the plastidial phosphorylase
New Phytologist, EarlyView.Summary The plastidial phosphorylase (Pho1 or Phs1; E.C. 2.4.1.1) is a ubiquitous enzyme among plants that catalyzes the formation and degradation of glucans. Although the first report connecting Pho1 with starch metabolism came out > 80 years ago, its precise role is still a matter of debate.
David Seung +2 more
wiley +1 more source