Results 121 to 130 of about 19,332 (219)
PLoS Neglected Tropical Diseases, 2010 BackgroundTrichomonas vaginalis has an unusually large genome (approximately 160 Mb) encoding approximately 60,000 proteins. With the goal of beginning to understand why some Trichomonas genes are present in so many copies, we characterized here a family
Jike Cui +3 more
doaj +1 more source
Biomedical Chromatography, Volume 40, Issue 12, December 2026.ABSTRACT An ultrahigh‐performance liquid chromatography coupled with quadrupole‐Orbitrap high‐resolution mass spectrometry (UHPLC‐Q‐Orbitrap HRMS) method was applied to characterize Pingchuanning (PCN) decoction and its absorbed serum constituents in asthmatic rats.
Yue Zhang +6 more
wiley +1 more source
Characterization of calcium regulated adenylyl cyclases
, 2018 Adenylyl cyclases are key points for the concurrent integration of diverse signaling pathways. Controlling production of the second messenger cAMP, adenylyl cyclases provide an important mechanism for the regulation of physiological functions by ...
Trevor B. Doyle (5929646) +1 more
core +2 more sources
Clinical and Translational Discovery, Volume 6, Issue 6, December 2026.• Integrative evaluation with proteomic analysis of mononuclear cells (MNC) from bone marrow (BM) or peripheral blood (PB) sources for autologous cell implantation in patients with chronic wounds sheds light on molecular differences and clinical outcomes. • BM‐MNC and PB‐MNC exhibited distinct and source‐specific proteomic signatures.
Farina Mohamad Yusoff +9 more
wiley +1 more source
β-Nicotinamide adenine dinucleotide (β-NAD) acts as a bronchodilator.
PLoS ONEIntroductionβ-Nicotinamide adenine dinucleotide (β-NAD) is recognized as a sympathetic neurotransmitter that relaxes vascular and intestinal smooth muscle through purinergic receptor pathways. In the lung, β-NAD has been associated with anti-inflammatory
Innokentij Jurastow +12 more
doaj +1 more source
The Love Story between Orai Calcium Entry Channels and Adenylyl Cyclases Gets even more Complicated. [PDF]
Function (Oxf), 2021 Hofer AM.
europepmc +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10977-10991, December 2026.ABSTRACT Aims Incretin‐based pharmacotherapy was initially developed to improve glucose‐dependent insulin secretion and glycaemic control in type 2 diabetes, but its clinical interpretation has expanded substantially with cardiovascular outcome trials, kidney outcome data, obesity studies and next‐generation polyagonist development.
Ferenc Sztanek +3 more
wiley +1 more source
CellsCyclic nucleotide signaling pathways play essential roles in the physiology of the nematode Caenorhabditis elegans, influencing processes such as reproduction, environmental sensing, and cellular homeostasis. The intracellular levels of cAMP and cGMP are
Kranti K. Galande, Rick H. Cote
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Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.Polysaccharide extraction from Alhagi camelorum Fisch. was optimized, yielding ACP‐II‐1, a novel GalA‐rich, HG‐dominant pectin (26.145 kDa) containing branched RG‐I domains. ACP‐II‐1 reduced melanogenesis in forskolin‐stimulated B16F10 cells and a zebrafish model.
Zhitao Liu +4 more
wiley +1 more source
Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases [PDF]
, 1998 The active sites of guanylyl and adenylyl cyclases are closely related. The crystal structure of adenylyl cyclase and modeling studies suggest that specificity for ATP or GTP is dictated in part by a few amino acid residues, invariant in each family ...
Garbers, D. L. +5 more
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