Results 21 to 30 of about 171,177 (219)
TGF-β/SMAD signaling regulation of mesenchymal stem cells in adipocyte commitment
Stem cell research & therapeutics, 2020 Adipocytes arising from mesenchymal stem cells (MSCs) requires MSC adipocyte commitment and differentiation of preadipocytes to mature adipocytes. Several signaling and some cytokines affect the adipogenesis of MSCs.
Sheng-Nan Li, Jia-fa Wu
semanticscholar +1 more source
Adipocyte, 2012 When Ron Landes approached me last summer with the idea to launch a journal dedicated to adipose tissue research, it resonated immediately; I loved the idea. Thus, it is with great pleasure that we launch Adipocyte, the first international peer-reviewed multi-disciplinary journal to focus exclusively on research covering all aspects of adipose tissue ...
openaire +3 more sources
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis
Oncogene, 2018 Ovarian cancer (OvCa) is characterized by widespread and rapid metastasis in the peritoneal cavity. Visceral adipocytes promote this process by providing fatty acids (FAs) for tumour growth.
A. Ladányi +13 more
semanticscholar +1 more source
Cell Metabolism, 2010 We are pleased to present in this issue of Cell Metabolism a review series on brown adipocytes. Until recently, brown adipose tissue (BAT) was principally studied by a handful of investigators focused on rodents and newborn mammals, and, at times, their work was deemed more an exercise in scientific curiosity than an issue relevant to human health.
Charlotte Wang, Nikla Emambokus
openaire +3 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2001 Adipocyte complement-related protein (30 kDa) (Acrp30), a secreted protein of unknown function, is exclusively expressed in differentiated adipocytes; its mRNA is decreased in obese humans and mice.
J. Fruebis +7 more
semanticscholar +1 more source
Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins.
Cancer Discovery, 2018 Advanced, metastatic melanomas frequently grow in subcutaneous tissues and portend a poor prognosis. Though subcutaneous tissues are largely composed of adipocytes, the mechanisms by which adipocytes influence melanoma are poorly understood.
Maomao Zhang +21 more
semanticscholar +1 more source
Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Nature Communications, 2020 White adipose tissue (WAT) expansion in obesity occurs through enlargement of preexisting adipocytes (hypertrophy) and through formation of new adipocytes (adipogenesis).
Shengpeng Wang +16 more
semanticscholar +1 more source
Adipocyte metabolism and obesity [PDF]
Journal of Lipid Research, 2009 Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity.
Alan D. Attie, Philipp E. Scherer
openaire +3 more sources
Extracting quantitative biological information from brightfield cell images using deep learning [PDF]
, 2020 Quantitative analysis of cell structures is essential for biomedical and pharmaceutical research. The standard imaging approach relies on fluorescence microscopy, where cell structures of interest are labeled by chemical staining techniques. However, these techniques are often invasive and sometimes even toxic to the cells, in addition to being time ...
arxiv +1 more source
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.
Genes & Development, 1994 Previously, we have isolated and characterized an enhancer from the 5'-flanking region of the adipocyte P2 (aP2) gene that directs high-level adipocyte-specific gene expression in both cultured cells and transgenic mice.
P. Tontonoz +4 more
semanticscholar +1 more source