Results 61 to 70 of about 171,177 (219)

CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors

open access: yesNature Communications, 2017
Adipose tissue resident macrophages have important roles in the maintenance of tissue homeostasis and regulate insulin sensitivity for example by secreting pro-inflammatory or anti-inflammatory cytokines. Here, we show that M2-like macrophages in adipose
A. Nawaz   +25 more
semanticscholar   +1 more source

MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation.

open access: yesJournal of Clinical Investigation, 2015
Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in osteogenesis that is accompanied by an increased propensity toward adipocyte differentiation. This switch increases adipocyte numbers and decreases the number of osteoblasts,
Changjun Li   +11 more
semanticscholar   +1 more source

Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism

open access: yesScience Signaling, 2018
Parkin-mediated mitophagy reverses the browning of white adipose tissue. A whitener for beige fat White fat can undergo “browning” and acquire some of the energy-burning properties of brown fat in response to various stimuli, such as β3-adrenergic ...
Xiaodan Lu   +8 more
semanticscholar   +1 more source

Rapid Depot-Specific Activation of Adipocyte Precursor Cells at the Onset of Obesity

open access: yesNature Cell Biology, 2015
Excessive accumulation of white adipose tissue (WAT) is the defining characteristic of obesity. WAT mass is composed primarily of mature adipocytes, which are generated through the proliferation and differentiation of adipocyte precursors (APs). Although
Elise Jeffery   +4 more
semanticscholar   +1 more source

Branched chain amino acid catabolism fuels adipocyte differentiation and lipogenesis

open access: yesNature Chemical Biology, 2015
Adipose tissue plays important roles in regulating carbohydrate and lipid homeostasis, though less is known about the regulation of amino acid metabolism in adipocytes.
Courtney R. Green   +6 more
semanticscholar   +1 more source

Quantitative assessment of adipocyte differentiation in cell culture

open access: yesAdipocyte, 2016
Adipocyte cell culture is an important tool for mechanistic studies of energy metabolism. Many factors affect the differentiation of adipocytes in culture. Oil red O staining can be used to assess the degree of differentiation.
Nils A Kraus   +5 more
semanticscholar   +1 more source

Large Field, High Resolution Full Field Optical Coherence Tomography: A Pre-clinical study of human breast tissue and cancer assessment [PDF]

open access: yesarXiv, 2012
We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) is used to image human breast tissue and is evaluated to assess its ability to aid the pathologist's management of intra-operative diagnoses.
arxiv  

Interleukin-6/STAT3 signalling regulates adipocyte induced epithelial-mesenchymal transition in breast cancer cells

open access: yesScientific Reports, 2018
The tumour microenvironment is a key regulators of tumour progression through the secretion of growth factors that activate epithelial-mesenchymal transition (EMT). Induction of EMT is a key step for transition from a benign state to a metastatic tumour.
Jones Gyamfi   +3 more
semanticscholar   +1 more source

Stimulation of triacylglycerol synthesis in rat adipocytes by plasma very-low-density lipoproteins [PDF]

open access: green, 1978
P Thomopoulos   +4 more
openalex   +1 more source

Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation

open access: yesNature Communications, 2018
Adipocytes undergo pronounced changes in size and behavior to support diverse tissue functions, but the mechanisms that control these changes are not well understood.
Rachel K. Zwick   +11 more
semanticscholar   +1 more source

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