Results 21 to 30 of about 39,170 (208)

Defective insulin-stimulated GLUT4 translocation in brown adipocytes induces systemic glucose homeostasis dysregulation independent of thermogenesis in female mice

open access: yesMolecular Metabolism, 2021
Objective: Recent studies indicate that brown adipose tissue, in addition to its role in thermogenesis, has a role in the regulation of whole-body metabolism.
Belén Picatoste   +6 more
doaj   +1 more source

Adipocytes and Stromal Cells Regulate Brown Adipogenesis Through Secretory Factors During the Postnatal White-to-Brown Conversion of Adipose Tissue in Syrian Hamsters

open access: yesFrontiers in Cell and Developmental Biology, 2021
Brown adipose tissue (BAT) is a specialized tissue that regulates non-shivering thermogenesis. In Syrian hamsters, interscapular adipose tissue is composed primarily of white adipocytes at birth, which is converted to BAT through the proliferation and ...
Junnosuke Mae   +6 more
doaj   +1 more source

Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]

open access: yesPLoS ONE, 2013
Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura   +6 more
doaj   +1 more source

Brown Adipocyte Focus [PDF]

open access: yesCell Metabolism, 2010
We are pleased to present in this issue of Cell Metabolism a review series on brown adipocytes. Until recently, brown adipose tissue (BAT) was principally studied by a handful of investigators focused on rodents and newborn mammals, and, at times, their work was deemed more an exercise in scientific curiosity than an issue relevant to human health.
Emambokus, Nikla, Wang, Charlotte
openaire   +2 more sources

Identification of Biochemical Differences in White and Brown Adipocytes Using FTIR Spectroscopy

open access: yesApplied Sciences, 2022
This study was conducted to investigate the developmental characteristics of adipocytes and to identify selectively white and brown adipocytes through Fourier transform infrared (FTIR) spectroscopy.
DongHyun Shon   +3 more
doaj   +1 more source

Full activation of thermogenesis in brown adipocytes requires Basigin action [PDF]

open access: yes, 2023
Exploring mechanisms responsible for brown adipose tissue's (BAT) high metabolic activity is crucial to exploit its energy-dissipating ability for therapeutic purposes.
Hansen, Jacob B   +40 more
core   +1 more source

The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function

open access: yesFrontiers in Endocrinology, 2023
IntroductionBrown adipocytes produce heat through non shivering thermogenesis (NST). To adapt to temperature cues, they possess a remarkably dynamic metabolism and undergo substantial cellular remodeling.
Zeynep Koçberber   +5 more
doaj   +1 more source

Compartmentalisation of cAMP in Brown Adipocytes [PDF]

open access: yes, 2022
The second messenger, 3',5'-cyclic adenosine monophosphate (cAMP) plays an important role in governing the function and differentiation of brown adipocytes.
Arcot Kannabiran, Sukanya
core   +1 more source

NF-κB regulates brown adipocyte function through suppression of ANT2

open access: yesActa Pharmaceutica Sinica B, 2022
The transcription factor nuclear factor of kappa-light-chain-enhancer of activated B cells (NF-κB) is expressed in brown adipocytes, but its role remains largely unknown in the cells.
Shiqiao Peng   +10 more
doaj   +1 more source

Src family kinases suppress differentiation of brown adipocytes and browning of white adipocytes [PDF]

open access: yesGenes to Cells, 2016
Brown adipocytes and beige adipocytes can expend energy, generate heat, and increase whole‐body energy expenditure. The detailed mechanisms of adipogenesis and thermogenesis of these cells are still obscure. Here, we show that Src family kinases (SFKs) regulate both brown adipogenesis and browning of white adipocytes.
Mai, Usui   +2 more
openaire   +2 more sources

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