Heritability of fat accumulation in white adipocytes [PDF]
American Journal of Physiology-Endocrinology and Metabolism, 2014 Since individual cells from freshly isolated white adipose tissue (WAT) exhibit variable levels of fat accumulation, we attempted to determine which factor(s) cause this variation. We used primary WAT cells from adult mice and the mouse 3T3-L1 cell-line of preadipocytes for these studies.
Liora S, Katz +2 more
openaire +4 more sources
Mitochondria in White, Brown, and Beige Adipocytes [PDF]
Stem Cells International, 2016 Mitochondria play a key role in energy metabolism in many tissues, including cardiac and skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be identified in mammals, commonly classified according to their colour appearance: the white (WAT), the brown (BAT), and the beige/brite/brown‐like (bAT) adipose tissues.
Miroslava Cedikova +7 more
core +6 more sources
Human White Adipocytes Convert Into “Rainbow” Adipocytes In Vitro [PDF]
Journal of Cellular Physiology, 2017 White adipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo. These plastic properties could be used in future for regenerative medicine, but are incompletely explored in their details.
Maurizi G +17 more
core +9 more sources
Oncostatin M promotes lipolysis in white adipocytes [PDF]
Adipocyte, 2022 Oncostatin M (OSM) is a member of the glycoprotein 130 cytokine family that is involved in chronic inflammation and increased in adipose tissue under obesity and insulin resistance. OSM was shown to inhibit adipogenesis, suppress browning, and contribute to insulin resistance in cultured white adipocytes.
van Krieken, Pim P +4 more
core +7 more sources
Identification of Biochemical Differences in White and Brown Adipocytes Using FTIR Spectroscopy [PDF]
Applied Sciences, 2022 This study was conducted to investigate the developmental characteristics of adipocytes and to identify selectively white and brown adipocytes through Fourier transform infrared (FTIR) spectroscopy.
DongHyun Shon +3 more
doaj +2 more sources
AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype. [PDF]
PLoS ONE, 2016 Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin.
Omar Abdul-Rahman +18 more
doaj +3 more sources
Mitophagy Mediates the Beige to White Transition of Human Primary Subcutaneous Adipocytes Ex Vivo [PDF]
Pharmaceuticals, 2022 Brown and beige adipocytes have multilocular lipid droplets, express uncoupling protein (UCP) 1, and promote energy expenditure. In rodents, when the stimulus of browning subsides, parkin-dependent mitophagy is activated and dormant beige adipocytes ...
Attila Vámos +9 more
doaj +2 more sources
Epigenetic Regulators of White Adipocyte Browning [PDF]
Epigenomes, 2021 Adipocytes play an essential role in maintaining energy homeostasis in mammals. The primary function of white adipose tissue (WAT) is to store energy; for brown adipose tissue (BAT), primary function is to release fats in the form of heat.
Ravikanth Nanduri
doaj +3 more sources
Adrenoceptors in white, brown, and brite adipocytes [PDF]
British Journal of Pharmacology, 2019 Adrenoceptors play an important role in adipose tissue biology and physiology that includes regulating the synthesis and storage of triglycerides (lipogenesis), the breakdown of stored triglycerides (lipolysis), thermogenesis (heat production), glucose metabolism, and the secretion of adipocyte‐derived hormones that can control whole‐body energy ...
Bronwyn A. Evans +3 more
openaire +4 more sources
Intrinsic Properties of Brown and White Adipocytes Have Differential Effects on Macrophage Inflammatory Responses [PDF]
Mediators of Inflammation, 2017 Obesity is marked by chronic, low-grade inflammation. Here, we examined whether intrinsic differences between white and brown adipocytes influence the inflammatory status of macrophages.
Louisa Dowal +13 more
doaj +2 more sources