Results 11 to 20 of about 62,660 (267)

Epigenetic Regulators of White Adipocyte Browning [PDF]

Epigenomes, 2021
Adipocytes play an essential role in maintaining energy homeostasis in mammals. The primary function of white adipose tissue (WAT) is to store energy; for brown adipose tissue (BAT), primary function is to release fats in the form of heat.
Ravikanth Nanduri
doaj   +3 more sources

Mitochondria in White, Brown, and Beige Adipocytes [PDF]

Stem Cells International, 2016
Mitochondria play a key role in energy metabolism in many tissues, including cardiac and skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be identified in mammals, commonly classified according to their colour appearance: the white (WAT), the brown (BAT), and the beige/brite/brown‐like (bAT) adipose tissues.
Miroslava Cedikova, Michaela Kripnerová, Jana Dvorakova, Pavel Pitule, Martina Grundmanova, Vaclav Babuska, Dana Mullerova, Jitka Kuncova   +7 more
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AMP-Activated Kinase (AMPK) Activation by AICAR in Human White Adipocytes Derived from Pericardial White Adipose Tissue Stem Cells Induces a Partial Beige-Like Phenotype. [PDF]

PLoS ONE, 2016
Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin.
Omar Abdul-Rahman, Endre Kristóf, Quang-Minh Doan-Xuan, András Vida, Lilla Nagy, Ambrus Horváth, József Simon, Tamás Maros, István Szentkirályi, Lehel Palotás, Tamás Debreceni, Péter Csizmadia, Tamás Szerafin, Tamás Fodor, Magdolna Szántó, Attila Tóth, Borbála Kiss, Zsolt Bacsó, Péter Bai   +18 more
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Identification of Biochemical Differences in White and Brown Adipocytes Using FTIR Spectroscopy

Applied Sciences, 2022
This study was conducted to investigate the developmental characteristics of adipocytes and to identify selectively white and brown adipocytes through Fourier transform infrared (FTIR) spectroscopy.
DongHyun Shon, SeJun Park, SukJun Yoon, Yong Ko   +3 more
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Mitophagy Mediates the Beige to White Transition of Human Primary Subcutaneous Adipocytes Ex Vivo

Pharmaceuticals, 2022
Brown and beige adipocytes have multilocular lipid droplets, express uncoupling protein (UCP) 1, and promote energy expenditure. In rodents, when the stimulus of browning subsides, parkin-dependent mitophagy is activated and dormant beige adipocytes ...
Attila Vámos, Abhirup Shaw, Klára Varga, István Csomós, Gábor Mocsár, Zoltán Balajthy, Cecília Lányi, Zsolt Bacso, Mária Szatmári-Tóth, Endre Kristóf   +9 more
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Heterogeneity of white adipocytes in metabolic disease

Current Opinion in Clinical Nutrition & Metabolic Care, 2023
Purpose of review This review aims to discuss the most recent evidence identifying the presence of distinct white adipocyte subpopulations in white adipose tissue (WAT) and how these may be altered with increasing adiposity and/or metabolic disease.
Bilson, Josh, Sethi, Jaswinder K., Byrne, Christopher D.   +2 more
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Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice. [PDF]

PLoS ONE, 2013
Chronic adrenergic activation leads to the emergence of beige adipocytes in some depots of white adipose tissue in mice. Despite their morphological similarities to brown adipocytes and their expression of uncoupling protein 1 (UCP1), a thermogenic ...
Yuko Okamatsu-Ogura, Keigo Fukano, Ayumi Tsubota, Akihiro Uozumi, Akira Terao, Kazuhiro Kimura, Masayuki Saito   +6 more
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Functional and Genetic Characterization of Porcine Beige Adipocytes

Cells, 2022
Beige adipocytes are a distinct type of fat cells with a thermogenic activity that have gained substantial attention as an alternative cellular anti-obesity target in humans.
Lilan Zhang, Silu Hu, Chunwei Cao, Chuanhe Chen, Jiali Liu, Yu Wang, Jianfeng Liu, Jianguo Zhao, Cong Tao, Yanfang Wang   +9 more
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Ceiling culture of human mature white adipocytes with a browning agent: A novel approach to induce transdifferentiation into beige adipocytes

Frontiers in Bioengineering and Biotechnology, 2022
Excess and dysfunctional adipose tissue plays an important role in metabolic diseases, including obesity, atherosclerosis and type 2 diabetes mellitus. In mammals, adipose tissue is categorized into two types: white and brown.
Yufei He, Zhuokai Liang, Jing Wang, Haojing Tang, Jian Li, Junrong Cai, Yunjun Liao   +6 more
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Human abdominal subcutaneous-derived active beige adipocytes carrying FTO rs1421085 obesity-risk alleles exert lower thermogenic capacity

Frontiers in Cell and Developmental Biology, 2023
Introduction: White adipocytes store lipids, have a large lipid droplet and few mitochondria. Brown and beige adipocytes, which produce heat, are characterized by high expression of uncoupling protein (UCP) 1, multilocular lipid droplets, and large ...
Attila Vámos, Attila Vámos, Rini Arianti, Rini Arianti, Boglárka Ágnes Vinnai, Boglárka Ágnes Vinnai, Rahaf Alrifai, Rahaf Alrifai, Abhirup Shaw, Szilárd Póliska, Andrea Guba, Andrea Guba, Éva Csősz, István Csomós, Gábor Mocsár, Cecilia Lányi, Zoltán Balajthy, László Fésüs, Endre Kristóf   +18 more
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