Results 121 to 130 of about 352,221 (407)

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]

open access: yes, 2007
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C.   +12 more
core   +1 more source

Bone marrow adipocytes

open access: yesAdipocyte, 2017
Adipocytes were identified in human bone marrow more than a century ago, yet until recently little has been known about their origin, development, function or interactions with other cells in the bone marrow.
M. Horowitz   +10 more
semanticscholar   +1 more source

Synergistic Combination of Tamoxifen–Tetraphenylethylene Co‐Assembled Micelles and Orlistat‐Induced Lipid Droplet Inhibition to Overcome Tamoxifen Resistance

open access: yesAdvanced Healthcare Materials, EarlyView.
Molecule 2, which contains a shorter oligoether chain, binds to tamoxifen via structural similarity forming micelles with a positive surface charge, thereby enhancing cellular uptake. These fluorescent micelles induce lipid droplet (LD) accumulation, exhibit strong fluorescence, and effectively overcome tamoxifen resistance by synergizing with orlistat‐
Jung Yeon Park   +4 more
wiley   +1 more source

In vivo tracking of adipose tissue grafts with cadmium-telluride quantum dots

open access: yesArchives of Plastic Surgery, 2018
Background Fat grafting, or lipofilling, represent frequent clinically used entities. The fate of these transplants is still not predictable, whereas only few animal models are available for further research.
Claus J. Deglmann   +8 more
doaj   +1 more source

Adipocyte Specific HO-1 Gene Therapy Is Effective in Antioxidant Treatment of Insulin Resistance and Vascular Function in an Obese Mice Model

open access: yesAntioxidants, 2020
Obesity is a risk factor for vascular dysfunction and insulin resistance. The study aim was to demonstrate that adipocyte-specific HO-1 (heme oxygenase-1) gene therapy is a therapeutic approach for preventing the development of obesity-induced metabolic ...
Shailendra P. Singh   +9 more
doaj   +1 more source

Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways. [PDF]

open access: yes, 2004
Insulin stimulation of adipocytes resulted in the recruitment of atypical PKC (PKCzeta/lambda) to plasma membrane lipid raft microdomains. This redistribution of PKCzeta/lambda was prevented by Clostridium difficile toxin B and by cholesterol depletion ...
Hwang, Joseph B   +4 more
core   +1 more source

Reporting guidelines, review of methodological standards, and challenges toward harmonization in bone marrow adiposity research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society [PDF]

open access: yes, 2020
The interest in bone marrow adiposity (BMA) has increased over the last decade due to its association with, and potential role, in a range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation ...
et al,   +2 more
core   +1 more source

Relationship between adipose tissue dysfunction, Vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease [PDF]

open access: yes, 2017
Non-alcoholic fatty liver disease ( NAFLD) is the most common chronic liver disease worldwide. Its pathogenesis is complex and not yet fully understood.
BARCHETTA, ILARIA   +7 more
core   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

open access: yesAdvanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi   +8 more
wiley   +1 more source

Anterior pituitary influence on adipokine expression and secretion by porcine adipocytes

open access: yesAnimal, 2016
Nutritional stressors may cause negative effects on animal health and growth and lead to significant economic impact. Adipose tissue is an endocrine organ producing, mediators and hormones, called adipokines.
R. Saleri   +3 more
doaj   +1 more source

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