Results 61 to 70 of about 160,546 (318)

Effect of the chronic administration of caffeine on adipose mass and lipid profile of Wistar rats - doi: 10.4025/actascibiolsci.v35i2.11085

open access: yesActa Scientiarum: Biological Sciences, 2012
This work aimed at verifying the effect of the chronic ingestion of caffeine on body weight and adiposity of Wistar rats. Sixteen male Wistar rats weighting on average 240 g were divided into two groups, one control and the other caffeine-treated (5 mg ...
Priscila Nakagawa   +1 more
doaj   +1 more source

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

open access: yesAdvanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari   +11 more
wiley   +1 more source

Association of environmental exposure to perchlorate, nitrate, and thiocyanate with overweight/obesity and central obesity among children and adolescents in the United States of America using data from the National Health and Nutrition Examination Survey (NHANES) 2005–2016

open access: yesNew Directions for Child and Adolescent Development, Volume 2022, Issue 185-186, Page 107-122, November 2022., 2022
Abstract The association of overweight/obesity, and central obesity with thiocyanate (SCN), perchlorate (CIO), and nitrate (NO) in childhood and adolescence is unclear. Therefore, this study aimed to explore this association in 4447 participants comprising children and adolescents (aged 6–19 years) using data from the United States National Health and ...
Qi Jiang, Qin Li
wiley   +1 more source

Antioxidant and Anti‐Senescence Polyvinyl Alcohol‐Gallic Acid Supramolecular Hydrogels for Stem Cell Culture

open access: yesAdvanced Healthcare Materials, EarlyView.
The PVA‐GA hydrogel is formed through hydrogen bonding between PVA hydroxyl groups and GA galloyl units, enabling sustainable GA release and its extended biological activity. The hydrogel scavenges ROS to reduce oxidative stress, preventing mitochondrial damage from excessive ROS, mitigating hADSC senescence, and preserving VEGF secretion, offering a ...
Yiduo Zhou   +11 more
wiley   +1 more source

The effect of exercise training on endothelial function in postmenopausal women with breast cancer under aromatase inhibitor therapy

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4946-4953, December 2022., 2022
Exercise training led to significantly greater improvement in exercise capacity in postmenopausal women with aromatase inhibitor‐treated breast cancer than exercise counseling only, none the less it did not exert any measurable effects on endothelial dysfunction Abstract Background Breast cancer is the leading non‐cardiovascular cause of death in women.
Barbara Mayr   +3 more
wiley   +1 more source

Supercritical Fluid‐Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
These findings advance tissue repair by offering a multifunctional filler that improves large‐scale volume retention, elasticity, and support for vascularized tissue growth. The decellularized extracellular matrix (dECM)‐based material provides low injection force and minimizes swelling, ensuring sustained volume. Combining CMC with supercritical fluid‐
Seol‐Ha Jeong   +6 more
wiley   +1 more source

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

open access: yesAdvanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang   +14 more
wiley   +1 more source

The Chemerin Receptor CMKLR1 Requires Full‐Length Chemerin for High Affinity in Contrast to GPR1 as Demonstrated by a New Nanoluciferase‐Based Binding Assay

open access: yesChemMedChem, Volume 17, Issue 23, December 5, 2022., 2022
The adipokine chemerin and the short peptide agonist chemerin‐9 activate two GPCRs: CMKLR1 and GPR1. Here, we established a nanoluciferase based binding assay to analyze differences in ligand binding. For GPR1, both ligands show high affinity and comparable binding.
Anne Sophie Czerniak   +3 more
wiley   +1 more source

Tyramine activates lipid accumulation in rat adipocytes: influences of in vitro and in vivo administration

open access: yesAIMS Molecular Science, 2017
Tyramine is naturally occurring in foods. This biogenic amine is known to induce hypertension, especially when ingested by individuals treated by irreversible inhibitors of monoamine oxidases (MAO).
Francisco Les   +3 more
doaj   +1 more source

Contrôle paracrine du développement du tissu adipeux par l'autotaxine et l'acide lysophosphatidique [PDF]

open access: yesarXiv, 2006
Secretion and role of autotaxin and lysophosphatidic acid in adipose tissue In obesity, adipocyte hypertrophy is often associated with recrutement of new fat cells (adipogenesis) under the control of circulating and local regulatory factors. Among the different lipids released in the extracellular compartment of adipocytes, our group found the presence
arxiv  

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