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The FASEB Journal, Volume 40, Issue 2, 31 January 2026.This study conducted an integrated analysis using multi‐source data, with specific data sources including the GEO database (encompassing datasets GSE55235, GSE55457, and GSE152805), literature‐mined gene sets, and the IEU OpenGWAS database (dataset ebi‐a‐GCST005814).
Jiahong Li +9 more
wiley +1 more source
Biochemical and Physiological Effects of Galanin in Health and Disease
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles +3 more
wiley +1 more source
TNF/TNFR1 is a Key Regulator of Prolonged Fasting‐Induced Decrease in Adipose Tissue
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Fasting triggers an inflammatory response and increases sympathetic tone in white adipose tissue (WAT), promoting fat breakdown and tissue remodeling. Fasting sparks an inflammatory response that underpins the reduction in adipocyte size and WAT remodeling.
Amanda Carla Clemente de Oliveira +12 more
wiley +1 more source
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Chemerin – exploring a versatile adipokine
Biological chemistry, 2022Chemerin is a small chemotactic protein and a key player in initiating the early immune response. As an adipokine, chemerin is also involved in energy homeostasis and the regulation of reproductive functions.
Tobias F. Fischer +1 more
semanticscholar +1 more source
Obesity, 2021
The purpose of this study was to investigate the effects of vitamin D on adipokine expression and inflammation in human adipose tissues and adipocytes and evaluate the molecular mechanisms involved.
H. Nimitphong +4 more
semanticscholar +1 more source
The purpose of this study was to investigate the effects of vitamin D on adipokine expression and inflammation in human adipose tissues and adipocytes and evaluate the molecular mechanisms involved.
H. Nimitphong +4 more
semanticscholar +1 more source
2018
Brown adipokines are regulatory factors secreted by brown and beige adipocytes that exhibit endocrine, paracrine, and autocrine actions. Peptidic and non-peptidic molecules, including miRNAs and lipids, are constituents of brown adipokines. Brown adipose tissue remodeling to meet thermogenic needs is dependent on the secretory properties of brown/beige
Francesc, Villarroya +4 more
openaire +2 more sources
Brown adipokines are regulatory factors secreted by brown and beige adipocytes that exhibit endocrine, paracrine, and autocrine actions. Peptidic and non-peptidic molecules, including miRNAs and lipids, are constituents of brown adipokines. Brown adipose tissue remodeling to meet thermogenic needs is dependent on the secretory properties of brown/beige
Francesc, Villarroya +4 more
openaire +2 more sources
Theoretical biology forum, 2014
Once considered a passive reservoir for lipid storage and an inert provider of thermal/mechanical insulation, white adipose tissue (WAT) is presently seen as a highly dynamic endocrine organ that actively modulates a variety of physiologic processes, including energy balance, food intake, inflammation, immunity, metabolism, as well as cardio-vascular ...
Fietta, Pieranna, Delsante, Giovanni
openaire +2 more sources
Once considered a passive reservoir for lipid storage and an inert provider of thermal/mechanical insulation, white adipose tissue (WAT) is presently seen as a highly dynamic endocrine organ that actively modulates a variety of physiologic processes, including energy balance, food intake, inflammation, immunity, metabolism, as well as cardio-vascular ...
Fietta, Pieranna, Delsante, Giovanni
openaire +2 more sources
Clinica Chimica Acta, 2013
White adipose tissue is recognized as a dynamic endocrine organ able to produce and release several bioactive polypeptides known as adipokines. Obesity is defined as an excessive growth of adipose tissue. As such, it is likely that adipokines could play an important role in the development of diseases associated with obesity including insulin ...
Viviane de Oliveira, Leal, Denise, Mafra
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White adipose tissue is recognized as a dynamic endocrine organ able to produce and release several bioactive polypeptides known as adipokines. Obesity is defined as an excessive growth of adipose tissue. As such, it is likely that adipokines could play an important role in the development of diseases associated with obesity including insulin ...
Viviane de Oliveira, Leal, Denise, Mafra
openaire +2 more sources
Adipokines in vascular calcification
Clinica Chimica Acta, 2021Adipose tissue (AT), a critical endocrine gland, is capable of producing and secreting abundant adipokines. Adipokines act on distant or adjacent organ tissues via paracrine, autocrine, and endocrine mechanism, which play attractive roles in the regulation of glycolipid metabolism and inflammatory response. Increasing evidence shows that adipokines can
Xuan, Xiao +7 more
openaire +2 more sources