Results 21 to 30 of about 1,754 (193)

Immunohistochemical staining for adipophilin, perilipin and TIP47 [PDF]

Journal of Clinical Pathology, 2006
Background: The presence of lipid in the cell cytoplasm is useful for supporting the diagnosis of sebaceous gland carcinoma (SGC). Currently this requires histochemical stains that are carried out on frozen sections of unprocessed tissue.
K, Muthusamy, G, Halbert, F, Roberts
openaire   +2 more sources

Endoscopic features of the duodenal pyloric gland adenoma: A case series of 14 patients. [PDF]

DEN Open
Abstract Background Pyloric gland adenoma (PGA) is a distinct subtype of duodenal adenoma. PGA has been increasingly recognized as a histologically and molecularly distinct entity; however, its endoscopic features have not been precisely described. This study aims to investigate the endoscopic characteristics of duodenal PGA, including the association ...
Uozumi T, Nonaka S, Mizuguchi Y, Suzuki H, Abe S, Yoshinaga S, Sekine S, Saito Y.   +7 more
europepmc   +2 more sources

Isolation of Adipophilin and Butyrophilin from Bovine Milk and Characterization of a cDNA Encoding Adipophilin

Journal of Dairy Science, 1999
The milk fat globule membrane-associated proteins adipophilin (alias adipocyte differentiation-related protein) and butyrophilin were purified from bovine milk by reverse-phase chromatography. The nucleotide sequence of bovine adipophilin was obtained via peptide mapping and sequencing of a mammary gland cDNA clone, which comprises 1841 nucleotides and
Nielsen, R.L., Andersen, M.H., Mabhout, P., Berglund, L., Petersen, T.E., Rasmussen, J.T.; id_orcid 0000-0002-2809-7225   +5 more
openaire   +5 more sources

Screening for Kidney Cancer: Is There a Role for Aquaporin-1 and Adipophilin? [PDF]

Mayo Clinic Proceedings, 2010
In this issue of Mayo Clinic Proceedings, Morrissey et al1 report the most promising proof of concept yet for the use of urine-based markers in the diagnosis of renal cell carcinoma. They show that 2 proteins that are highly expressed by renal cell carcinoma, the water-channel aquaporin-1 (AQP1) and the lipid droplet–associated protein adipophilin ...
Stefan K, Grebe, Lori A, Erickson
openaire   +2 more sources

Homocysteine Promotes the Pathogenesis of Atherosclerosis through the Circ-PIAS1-5/miR-219a-2-3p/TEAD1 Axis. [PDF]

Adv Sci (Weinh)
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Ma S, Ma F, Ding N, Xie L, Yang A, Shen J, Jiao Y, Wu K, Chai Y, Bai Z, Xiong J, Li N, Zhang H, Jiang Y.   +13 more
europepmc   +2 more sources

Spatial Integration of TIP47 and Adipophilin in Macrophage Lipid Bodies [PDF]

Journal of Biological Chemistry, 2005
We studied the distribution of the PAT family proteins TIP47 and adipophilin in lipid bodies of THP-1 cell-derived macrophages using freeze-fracture immunolabeling and other techniques. Lipid bodies in macrophages comprise lipid droplets and extensive, previously scantily characterized sheet-like organelles, which we descriptively call "lipid sails ...
Horst, Robenek, Stefan, Lorkowski, Michael, Schnoor, David, Troyer   +3 more
openaire   +2 more sources

Histologic differentiation and mucin phenotype in white opaque substance-positive gastric neoplasias

Endoscopy International Open, 2015
Background and study aims: The authors previously reported that the white opaque substance (WOS) in gastric epithelial neoplasia was caused by accumulation of lipid droplets by immunohistochemical and immunoelectron microscopic studies of adipophilin ...
Tetsuya Ueo, Hirotoshi Yonemasu, Kenshi Yao, Tetsuya Ishida, Kazumi Togo, Yuka Yanai, Masahide Fukuda, Mitsuteru Motomura, Ryoich Narita, Kazunari Murakami   +9 more
doaj   +1 more source

Determinants of adipophilin function in milk lipid formation and secretion [PDF]

Trends in Endocrinology & Metabolism, 2011
In many species the lactating mammary gland is one of the most lipogenic organs of the body. The majority of the lipid produced during lactation is secreted into milk by a novel process of membrane envelopment of cytoplasmic lipid droplets (CLDs).
Brandi M, Chong, Philip, Reigan, Kasey D, Mayle-Combs, David J, Orlicky, James L, McManaman   +4 more
openaire   +2 more sources

Adipocyte differentiation-related protein is induced by LRP1-mediated aggregated LDL internalization in human vascular smooth muscle cells and macrophages

Journal of Lipid Research, 2007
Aggregated LDL (agLDL) is internalized by LDL receptor-related protein (LRP1) in vascular smooth muscle cells (VSMCs) and human monocyte-derived macrophages (HMDMs).
V. Llorente-Cortés, T. Royo, O. Juan-Babot, L. Badimon   +3 more
doaj   +1 more source

Proteomic insights into an expanded cellular role for cytoplasmic lipid droplets[S]

Journal of Lipid Research, 2010
Cytoplasmic lipid droplets (CLDs) are cellular structures composed of a neutral lipid core surrounded by a phospholipid monolayer of amphipathic lipids and a variety of proteins.
Brittany D.M. Hodges, Christine C. Wu
doaj   +1 more source