Results 41 to 50 of about 1,754 (193)

PAT family proteins pervade lipid droplet cores

open access: yesJournal of Lipid Research, 2005
The PAT family proteins, named after perilipin, adipophilin, and the tail-interacting protein of 47 kDa (TIP47), are implicated in intracellular lipid metabolism. They associate with lipid droplets, but how is completely unclear.
Horst Robenek   +2 more
doaj   +1 more source

Redistribution of macrophage cholesteryl ester hydrolase from cytoplasm to lipid droplets upon lipid loading1

open access: yesJournal of Lipid Research, 2005
Hydrolysis of intracellular cholesteryl esters (CEs) represents the first step in the removal of cholesterol from lipid-laden foam cells associated with atherosclerotic lesions.
Bin Zhao   +4 more
doaj   +1 more source

Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line

open access: yesJournal of Lipid Research, 2006
Transplacental transfer of maternal fatty acids is critical for fetal growth and development. In the placenta, a preferential uptake of fatty acids toward long-chain polyunsaturated fatty acids (LCPUFAs) has been demonstrated.
Kari Anne Risan Tobin   +5 more
doaj   +1 more source

Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis [PDF]

open access: yesJournal of Cell Science, 2006
The prevailing hypothesis of lipid droplet biogenesis proposes that neutral lipids accumulate within the lipid bilayer of the ER membrane from where they are budded off, enclosed by a protein-bearing phospholipid monolayer originating from the cytoplasmic leaflet of the ER membrane.
Horst, Robenek   +5 more
openaire   +2 more sources

The nature of the white opaque substance within colorectal neoplastic epithelium as visualized by magnifying endoscopy with narrow-band imaging

open access: yesEndoscopy International Open, 2016
Background and study aims: We previously reported our discovery of a white opaque substance (WOS) that is opaque to endoscopic light inside the epithelium while using magnifying endoscopy (ME) to examine gastric epithelial neoplasia.
Kentaro Imamura   +17 more
doaj   +1 more source

Disorder in Milk Proteins: Adipophilin and TIP47, Important Constituents of the Milk Fat Globule Membrane

open access: yes, 2020
Milk fat globules (MFGs), which are secreted by the epithelial cells of the lactating mammary glands, account for the most of the nutritional value of milk.
Alkarim, Saleh A.   +5 more
core   +1 more source

Adipophilin immunostain in BL and not-BL cases.

open access: yes, 2013
(A) BL is characterized by medium-sized cells with a monotonous cohesive pattern of growth, round nuclei with finely clumped and dispersed chromatin, a high proliferation rate and “starry-sky” appearance [Haematoxilin-eosin (H&E), original magnification (
Pier P. Piccaluga (309094)   +13 more
core   +1 more source

Identification of adipophilin as a potential plasma biomarker for colorectal cancer using label-free quantitative mass spectrometry and protein microarray. [PDF]

open access: yes, 2011
[Background]: The aim of this study was to identify a new plasma biomarker for use in early detection of colorectal cancer.[Methods]: Using the combination of hollow fiber membrane (HFM)-based low-molecular weight protein enrichment and two-dimensional ...
Ioka, Tatsuya   +37 more
core   +1 more source

Cytoplasmic lipid droplet accumulation in developing mammary epithelial cells: roles of adipophilin and lipid metabolism

open access: yesJournal of Lipid Research, 2007
PAT proteins (perilipin, adipophilin, and TIP47) are hypothesized to be critical regulators of lipid accumulation in eukaryotic cells. We investigated the developmental relationships between the expression of these proteins and cytoplasmic lipid droplet (
Tanya D. Russell   +6 more
doaj   +1 more source

Human papilloma virus infection and mismatch repair protein expression in sebaceous neoplasms of the genital area

open access: yesHistopathology, Volume 88, Issue 6, Page 1221-1228, May 2026.
This study establishes the role of high‐risk HPV infection in cutaneous sebaceous carcinoma of the genital area. An intraepithelial component in a subset of cases poses a challenge to distinguish the entity from squamous cell carcinoma in situ. Rarely, sebaceous neoplasia of the genital area is associated with Muir–Torre syndrome. Aims This study aimed
Katharina Wiedemeyer   +5 more
wiley   +1 more source

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