Results 51 to 60 of about 1,754 (193)

Adipophilin expression is an indicator of poor prognosis in patients with pancreatic ductal adenocarcinoma: An immunohistochemical analysis. [PDF]

, 2020
関西医科大学博士（医学）令和元年度Adipophilin is a lipid droplet-associated protein, and its expression has been correlated with aggressive clinical behavior in some types of carcinomas, though its role in pancreatic ductal adenocarcinoma (PDAC) has not been clarified ...
Ishida, Mitsuaki, Ryota, Hironori, Hirooka, Satoshi, Hashimoto, Yuki, 橋本, 祐 希, Kosaka, Hisashi, ハシモト, ユウキ, Matsui, Yoichi, Yanagimoto, Hiroaki, Yamaki, So, Yamamoto, Tomohisa, Tsuta, Koji, Kotsuka, Masaya, Satoi, Sohei   +13 more
core  

Development and Characterisation of a Starvation‐ and Exercise‐Induced Murine Model of Microvesicular Steatosis Relevant to Anorexia Nervosa

Liver International Communications, Volume 7, Issue 1, March 2026.
ABSTRACT Anorexia nervosa (AN) leads to severe dietary restriction, low body weight, and in many patients, hepatocellular steatosis. Clinically, hepatic fat in AN is usually macrovesicular, whereas microvesicular steatosis is more often associated with severe starvation and mitochondrial dysfunction.
Michiko Ishii, Kyoko Hoshikawa, Yuko Takeda, Taketo Nishina, Fumi Uchiyama, Fumiya Suzuki, Keita Maki, Tomohiro Katsumi, Hiroaki Haga, Yoshiyuki Ueno   +9 more
wiley   +1 more source

What the Eyelid Can Tell You: The Unexpected Initial Presentation of De Novo Stage IV Breast Carcinoma

Journal of Cutaneous Pathology, Volume 53, Issue 3, Page 248-253, March 2026.
ABSTRACT A 66‐year‐old female presented with seven months of progressive right upper eyelid (RUL) drooping and thickening of her right lower eyelid (RLL). MRI revealed soft tissue enhancement of the RUL and RLL pre‐septal planes without posterior extension.
Grace L. Casado, Eileen Xu, Maedot A. Haymete, Nicholas A. Ramey, Douglas J. Grider   +4 more
wiley   +1 more source

Characterization and Comparison of Milk Fat Globule Membrane Proteins, Whey Protein Concentrate, and Micellar Casein Concentrate

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
This study compared milk fat globule membrane protein (MFGMP) with whey protein concentrate (WPC) and micellar casein concentrate (MCC). The results revealed MFGMP's superior structural stability and amino acid profile, identified its unique proteomic landscape through label‐free quantification, and demonstrated its enhanced in vitro digestibility ...
Jiaming Wang, Xiaoguo Ji, Zhongbo Bian, Yuwei Liu, Wenliang Chen, Chuang Fan, Juan Li   +6 more
wiley   +1 more source

Screening of multiple myeloma by polyclonal rabbit anti-human plasmacytoma cell immunoglobulin. [PDF]

PLoS ONE, 2013
Antibody-based immunotherapy has been effectively used for tumor treatment. However, to date, only a few tumor-associated antigens (TAAs) or therapeutic targets have been identified.
Bo Mu, Huan Zhang, Xiaoming Cai, Junbao Yang, Yuewu Shen, Baofeng Chen, Suhua Liang   +6 more
doaj   +1 more source

Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland

Frontiers in Cell and Developmental Biology, 2022
Secretory epithelial cells (sMEC) in mammary glands of lactating animals secrete lipids by a novel apocrine mechanism in which cytoplasmic lipid droplets (LD) contact and are enveloped by elements of the apical plasma membrane (APM) before being released
Jenifer Monks, Jenifer Monks, David J. Orlicky, Andrew E. Libby, Monica Dzieciatkowska, Mark S. Ladinsky, James L. McManaman, James L. McManaman   +7 more
doaj   +1 more source

LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid β-oxidation of lipid droplets. [PDF]

PLoS ONE, 2012
Lipid storage droplet protein 5 (LSDP5) is a lipid droplet-associated protein of the PAT (perilipin, adipophilin, and TIP47) family that is expressed in the liver in a peroxisome proliferator-activated receptor alpha (PPARα)-dependent manner; however ...
Hang Li, Yue Song, Li-Jun Zhang, Yu Gu, Fan-Fan Li, Shu-Yi Pan, Li-Na Jiang, Fang Liu, Jing Ye, Qing Li   +9 more
doaj   +1 more source

High Immunohistochemical Expression of SETD5 as a Candidate Pathological Factor for Dedifferentiation and Prognosis in Liposarcoma

Pathology International, Volume 76, Issue 1, January 2026.
SET domain containing 5 (SETD5), a chromatin regulator involved in adipocytic differentiation. However, its immunohistochemical expression and prognostic significance in liposarcoma remain unclear. In our study, SETD5 expression was markedly elevated in the dedifferentiated component of dedifferentiated liposarcoma compared to the well‐differentiated ...
Makoto Abe, Naoto Kubota, Ken Yamazaki, Eisuke Miura, Kaoru Hirabayashi, Masatsugu Ishii, Hirofumi Shirakawa, Kazutaka Kikuta, Yudai Murayama, Rumi Nakagawa, Hidenori Ojima   +10 more
wiley   +1 more source

Integrated Transcriptomic Analysis Identifies Immune Remodeling and Prognostic Signatures in Uveal Melanoma

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Uveal melanoma (UVM) is the most common primary intraocular malignancy in adults and exhibits a high propensity for liver metastasis, often leading to poor prognosis. However, effective prognostic biomarkers and therapeutic strategies for metastatic UVM remain limited.
Zhongmin Li, Youmeng Yang, Houhong Wang, Jing Wang, Songyun Zhao   +4 more
wiley   +1 more source

High-Fructose Diet Increases Renal ChREBPβ Expression, Leading to Intrarenal Fat Accumulation in a Rat Model with Metabolic Syndrome

Biology, 2022
Fructose consumption is associated with metabolic syndrome (MeS). Dysregulated lipid metabolism and ectopic lipid accumulation, such as in “fatty liver’’, are pivotal components of the syndrome.
Ariel Bier, Eliyahu Shapira, Rawan Khasbab, Yehonatan Sharabi, Ehud Grossman, Avshalom Leibowitz   +5 more
doaj   +1 more source