Results 1 to 10 of about 4,507,088 (388)

Mitochondria transplanted adipose-derived stem cells/decellularized adipose tissue hydrogel for adipose tissue regeneration [PDF]

Materials Today Bio
Adipose tissue reconstruction is of significant importance for both cosmetic procedures and therapeutic interventions. Current clinical strategies, including autologous adipose tissue grafting and the application of synthetic materials, still have ...
Jiezhang Tang, Yige Han, Pan Ren, Lirong Xu, Zhanjun Lei, Jiaqi Li, Yiwei Cui, Jie Zhang, Jinqing Li, Xueyong Li   +9 more
doaj   +2 more sources

Clinical correlates of perivascular adipose tissue in coronary artery disease and obesity [PDF]

Frontiers in Physiology
The adipose tissue surrounding the arterial and venous vasculature and microvasculature affects vascular reactivity and pathology, particularly when perivascular adipose tissue (PVAT) accumulates in overweight and obese states.
Sunil Upadhaya, Amitabh C. Pandey, Jose Wiley, Thierry H. Le Jemtel   +3 more
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Adipose tissue remodeling: its role in energy metabolism and metabolic disorders

Frontiers in Endocrinology, 2016
The adipose tissue is a central metabolic organ in the regulation of whole-body energy homeostasis. The white adipose tissue (WAT) functions as a key energy reservoir for other organs, whereas the brown adipose tissue (BAT) accumulates lipids for cold ...
Sung Sik eChoe, Jin Young eHuh, In Jae eHwang, Jong In eKim, Jae Bum eKim   +4 more
doaj   +2 more sources

Human Adipose Tissue Metabolism in Obesity [PDF]

Journal of Obesity & Metabolic Syndrome
The scientific understanding of adipose tissue has advanced tremendously during the past decade. Once thought to be an inert fat storage organ, we now know that adipose tissue serves important functions in energy balance and endocrinology, as well as ...
Shuhao Lin, Michael D. Jensen
doaj   +2 more sources

Thermoneutral housing promotes hepatic steatosis in standard diet-fed C57BL/6N mice, with a less pronounced effect on NAFLD progression upon high-fat feeding

Frontiers in Endocrinology, 2023
IntroductionNon-alcoholic fatty liver disease (NAFLD) can progress to more severe stages, such as steatohepatitis and fibrosis. Thermoneutral housing together with high-fat diet promoted NAFLD progression in C57BL/6J mice.
Olga Horakova, Gabriella Sistilli, Gabriella Sistilli, Veronika Kalendova, Veronika Kalendova, Kristina Bardova, Marko Mitrovic, Marko Mitrovic, Tomas Cajka, Ilaria Irodenko, Petra Janovska, Karoline Lackner, Jan Kopecky, Martin Rossmeisl   +13 more
doaj   +1 more source

Adipose tissue-specific ablation of PGC-1β impairs thermogenesis in brown fat

Disease Models & Mechanisms, 2022
Impaired thermogenesis observed in mice with whole-body ablation of peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β; officially known as PPARGC1B) may result from impaired brown fat (brown adipose tissue; BAT) function, but other ...
Jiří Funda, Josep A. Villena, Kristina Bardova, Katerina Adamcova, Illaria Irodenko, Pavel Flachs, Ivana Jedlickova, Eliska Haasova, Martin Rossmeisl, Jan Kopecky, Petra Janovska   +10 more
doaj   +1 more source

Epicardial adipose tissue in contemporary cardiology

Nature Reviews Cardiology, 2022
Interest in epicardial adipose tissue (EAT) is growing rapidly, and research in this area appeals to a broad, multidisciplinary audience. EAT is unique in its anatomy and unobstructed proximity to the heart and has a transcriptome and secretome very ...
G. Iacobellis
semanticscholar   +1 more source

A pyrexic effect of FGF21 independent of energy expenditure and UCP1

Molecular Metabolism, 2021
Objective: Administration of FGF21 to mice reduces body weight and increases body temperature. The increase in body temperature is generally interpreted as hyperthermia, i.e.
Petr Zouhar, Petra Janovska, Sara Stanic, Kristina Bardova, Jiri Funda, Blanka Haberlova, Birgitte Andersen, Martin Rossmeisl, Barbara Cannon, Jan Kopecky, Jan Nedergaard   +10 more
doaj   +1 more source

Adipose tissue aging: mechanisms and therapeutic implications

Cell Death and Disease, 2022
Adipose tissue, which is the crucial energy reservoir and endocrine organ for the maintenance of systemic glucose, lipid, and energy homeostasis, undergoes significant changes during aging.
M. Ou, Hao Zhang, Poh-ching Tan, Shuangbai Zhou, Qing-Feng Li   +4 more
semanticscholar   +1 more source

Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle

Molecular Metabolism, 2023
Objective: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis.
Petra Janovska, Petr Zouhar, Kristina Bardova, Jakub Otahal, Marek Vrbacky, Tomas Mracek, Katerina Adamcova, Lucie Lenkova, Jiri Funda, Tomas Cajka, Zdenek Drahota, Sara Stanic, Arild C. Rustan, Olga Horakova, Josef Houstek, Martin Rossmeisl, Jan Kopecky   +16 more
doaj   +1 more source