Results 91 to 100 of about 1,797,998 (215)

Retinoic acid induces white adipose tissue browning by increasing adipose vascularity and inducing beige adipogenesis of PDGFRα+ adipose progenitors [PDF]

, 2017
Formation of beige adipocytes within white adipose tissue enhances energy expenditure, which is a promising strategy to reduce obesity and prevent metabolic symptoms.
Min Du, Fu, Xing, Tian, Qiyu, Zhao, Junxing, Gomez, Noe Alberto, Sophie C Trombetta, Deavila, Jeanene M., Xingwei Liang, Zhixiu Wang, Bo Wang, Du, Min, Qiyu Tian, Noe Alberto Gomez, Xing Fu, Liang, Xingwei, Liang Zhao, Wang, Bo, Junxing Zhao, Mei-Jun Zhu, Zhao, Liang, Wang, Zhixiu, Jeanene M Deavila, Trombetta, Sophie C., Zhu, Mei Jun   +23 more
core   +1 more source

Involvement of Alternative Splicing Regulation in Adipose Tissue Thermogenic Induction [PDF]

, 2023
[eng] Alternative splicing (AS) is a gene expression regulatory mechanism that enables generation of multiple mRNA isoforms from a single gene which commonly are translated into proteins.
Castellá Giner, Moisés
core   +1 more source

Combination Pharmacotherapies for Obesity—Current Evidence and Future Directions

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Combination pharmacotherapy for obesity can enhance weight loss by targeting complementary neuroendocrine and metabolic pathways. Such benefits are largely additive but limited by tolerability, cost and access. This review outlines practical clinical archetypes and a research agenda for safer, more precise and durable combination strategies across ...
A. B. M. Kamrul‐Hasan, Arnav Kalra, Nitin Kapoor, Deep Dutta, Kunal Mahajan, Robin Maskey, Syed Abbas Raza   +6 more
wiley   +1 more source

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

Cell Reports, 2013
The phenomenon of white fat "browning," in which certain white adipose tissue depots significantly increase gene expression for the uncoupling protein UCP1 and thus supposedly acquire thermogenic, fat-burning properties, has attracted considerable attention.
Irina G. Shabalina, Natasa Petrovic, Jasper M.A. de Jong, Anastasia V. Kalinovich, Barbara Cannon, Jan Nedergaard   +5 more
openaire   +3 more sources

The Role of β3-Adrenergic Receptors in Cold-Induced Beige Adipocyte Production in Pigs

Cells
After exposure to cold stress, animals enhance the production of beige adipocytes and expedite thermogenesis, leading to improved metabolic health.
Shuo Yang, Hong Ma, Liang Wang, Fang Wang, Jiqiao Xia, Dongyu Liu, Linlin Mu, Xiuqin Yang, Di Liu   +8 more
doaj   +1 more source

MRP8‐Cre Transgenic Mice Are Resistant to Weight Gain and Diet‐Induced Obesity Independently of Neutrophils

European Journal of Immunology, Volume 56, Issue 9, September 2026.
The MRP8Cre mouse model is frequently used to investigate the biology of neutrophils. This study reports that MRP8Cre transgenic have a lower body weight and improved metabolic health, especially after high fat diet feeding, which correlates with decreased Serpine1/PAI‐1 expression in metabolic organs. Image created with BioRender.com. ABSTRACT Obesity
Stephan Forisch, Fatemeh Soltani, Laia Salvat Costa, Beatriz M. Cardoso, Yaiza Moreno Galiano, Cedric Duval, Robert A. S. Ariëns, Navdeep S. Chandel, Mari T. Kaartinen, Stefanie K. Wculek   +9 more
wiley   +1 more source

Human brown adipose tissue: Classical brown rather than brite/beige?

, 2020
New Findings What is the topic of this review? It has been suggested that human brown adipose tissue (BAT) is more similar to the brite/beige adipose tissue of mice than to classical BAT of mice.
Nedergaard, Jan,, Jan Nedergaard, Jasper M. A. de Jong, Alexander W. Fischer, Natasa Petrovic, de Jong, Jasper M. A.,, Fischer, Alexander W.,, Cannon, Barbara,, Petrovic, Natasa,, Barbara Cannon   +9 more
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Effect of Intermittent Fasting on Weight Loss in Overweight and Obese Adults: A Systematic Review of Clinical Trials

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This systematic review screened 2307 records identified through PubMed, Cochrane Library, Google Scholar, and ScienceDirect, following PRISMA 2020 criteria. The search yielded 26 eligible clinical trials (24 RCTs, 2 non‐randomized studies) on intermittent fasting (TRE 16:8/20:4/14:10/18:6, alternate‐day fasting, and 5:2 fasting) for weight loss in ...
Hafiz Muhammad Irfan Manzoor, Muhammad Tauseef Sultan, Aneela Hameed, Ahmad Mujtaba Noman, Mahnoor Khalid, Maheen Kazmi, Aiman Sohail, Mohamed Fawzy Ramadan, Eliasse Zongo, Muhammad Abdul Rahim, Fahad Al‐Asmari   +10 more
wiley   +1 more source

Optical imaging for brown or beige adipose tissue

VIEW
AbstractCurrently, one in three adults worldwide may be obese or overweight. Obesity is characterized by an excess of energy‐storing white fat. An ingenious and sought‐after strategy against obesity is to activate energy‐consuming beige fat, which is converted from white fat or brown fat.
Jiamin Liu, Linjie Ni, Minmin Peng, Yiying Liang, Chan Lu, Hanying Zheng, Zicheng Huang, Jinde Zhang, Ronghe Chen   +8 more
openaire   +2 more sources

Investigation of effect of hyperinsulinaemia on adipose tissue microvasculature. [PDF]

, 2015
Background: Obesity in Qatar is amongst the highest globally and constitutes a serious health risk. Obese individuals are at greater risk of vascular disease compared to the lean, especially in the insulin resistant state.
Bakhamis, AAA
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