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In recent decades, obesity has become one of the most common metabolic diseases [...]
Javier Gómez-Ambrosi
doaj +4 more sources
Targeting adipose tissue [PDF]
Two different types of adipose tissues can be found in humans enabling them to respond to starvation and cold: white adipose tissue (WAT) is generally known and stores excess energy in the form of triacylglycerol (TG), insulates against cold, and serves ...
Haas Bodo +3 more
doaj +4 more sources
Ceramides in Adipose Tissue [PDF]
Adipose tissue is a key nutrient-sensing depot that regulates excess energy storage and consumption. Adipocytes, the key components of the adipose tissue, have unique ability to store excess energy in the form of triglycerides, sense systemic energy demands, and secrete factors (lipids, peptides, cytokines, and adipokines) to regulate other metabolic ...
Ying Li +3 more
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Adipose tissue macrophages: their role in adipose tissue remodeling [PDF]
Abstract This review summarizes the role of macrophages in adipose tissue remodeling, particularly focusing on the paracrine loop between adipocytes and macrophages. The adipose tissue secretes a large number of bioactive substances, adipocytokines, which may be involved in a variety of physiologic and pathologic processes.
Takayoshi, Suganami, Yoshihiro, Ogawa
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Adipose tissue macrophages: Regulators of adipose tissue immunometabolism during obesity
Background: Adipose tissue macrophages (ATMs) are a well characterized regulator of adipose tissue inflammatory tone. Previously defined by the M1 vs M2 classification, we now have a better understanding of ATM diversity that departs from the old ...
Sierra A. Nance +2 more
doaj +1 more source
Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy [PDF]
Obesity increases preeclampsia risk. Adipose tissue inflammation may contribute to the clinical syndrome of pre-eclampsia. We compared adipose tissue macrophage infiltration and release of pro-inflammatory adipokines in pre-eclampsia and healthy ...
Bray, Jack +6 more
core +1 more source
Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity
Obesity adversely affects bone and fat metabolism in mice and humans. Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) have been shown to improve glucose metabolism and bone homeostasis in obesity.
Andrea Benova +21 more
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A Differential Pattern of Batokine Expression in Perivascular Adipose Tissue Depots From Mice
Depending on its anatomical placement, perivascular adipose tissue (PVAT) has been found to possess features more (e.g., aortic thoracic) or less (e.g., aortic abdominal) similar to brown/beige adipose tissue in mice, whereas PVAT surrounding the ...
Alberto Mestres-Arenas +12 more
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Protective Role of S-Adenosylmethionine Against Fructose-Induced Oxidative Damage in Obesity [PDF]
Introduction. It has been shown that S-adenosylmethionine (S-AMe) stimulates glutathione synthesis and increases cell resistance to the cytotoxic action of free radicals and pro-inflammatory cytokines. The aim of this study was to determine the effect of
Bratoeva, Kameliya Zh +3 more
core +4 more sources
We found previously that white adipose tissue (WAT) hyperplasia in obese mice was limited by dietary omega-3 polyunsaturated fatty acids (omega-3 PUFA). Here we aimed to characterize the underlying mechanism.
Katerina Adamcova +7 more
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