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Biomedicines, 2021 Adipose tissue resides in specific depots scattered in peripheral or deeper locations all over the body and it enwraps most of the organs. This tissue is always in a dynamic evolution as it must adapt to the metabolic demand and constraints.
Annie Ladoux +3 more
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Adipose tissue macrophages: Regulators of adipose tissue immunometabolism during obesity
Molecular Metabolism, 2022 Background: Adipose tissue macrophages (ATMs) are a well characterized regulator of adipose tissue inflammatory tone. Previously defined by the M1 vs M2 classification, we now have a better understanding of ATM diversity that departs from the old ...
Sierra A. Nance +2 more
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Omega-3 PUFAs prevent bone impairment and bone marrow adiposity in mouse model of obesity
Communications Biology, 2023 Obesity adversely affects bone and fat metabolism in mice and humans. Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) have been shown to improve glucose metabolism and bone homeostasis in obesity.
Andrea Benova +21 more
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A Differential Pattern of Batokine Expression in Perivascular Adipose Tissue Depots From Mice
Frontiers in Physiology, 2021 Depending on its anatomical placement, perivascular adipose tissue (PVAT) has been found to possess features more (e.g., aortic thoracic) or less (e.g., aortic abdominal) similar to brown/beige adipose tissue in mice, whereas PVAT surrounding the ...
Alberto Mestres-Arenas +12 more
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Perivascular Adipose Tissue [PDF]
, 2019 Key Concepts:- While traditionally viewed as little more than a simple lipid reserve, perivascular adipose tissue (PVAT) boasts an extensive biological arsenal which when mobilized can modulate vascular function.- PVAT dysfunction in disease is associated with alteration to its secretory profile which can create a contractile and pro-inflammatory ...
Javed, Saad +2 more
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Marine Drugs, 2018 We found previously that white adipose tissue (WAT) hyperplasia in obese mice was limited by dietary omega-3 polyunsaturated fatty acids (omega-3 PUFA). Here we aimed to characterize the underlying mechanism.
Katerina Adamcova +7 more
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Beige Adipose Tissue Identification and Marker Specificity—Overview
Frontiers in Endocrinology, 2021 Adipose tissue (AT) is classified based on its location, physiological and functional characteristics. Although there is a clear demarcation of anatomical and molecular features specific to white (WAT) and brown adipose tissue (BAT), the factors that ...
Anna-Claire Pilkington +4 more
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Frontiers in Physiology, 2018 Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic regimen of regular exercise and pharmaceutical treatment is often recommended for their clinical management.
Luana G. Leal +4 more
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Adipose tissue aging is regulated by an altered immune system
Frontiers in Immunology, 2023 Adipose tissue is a widely distributed organ that plays a critical role in age-related physiological dysfunctions as an important source of chronic sterile low-grade inflammation. Adipose tissue undergoes diverse changes during aging, including fat depot
Yi-Xiang Zhang +5 more
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Adipose tissue macrophages: their role in adipose tissue remodeling [PDF]
Journal of Leukocyte Biology, 2010 Abstract This review summarizes the role of macrophages in adipose tissue remodeling, particularly focusing on the paracrine loop between adipocytes and macrophages. The adipose tissue secretes a large number of bioactive substances, adipocytokines, which may be involved in a variety of physiologic and pathologic processes.
Takayoshi, Suganami, Yoshihiro, Ogawa
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