Results 31 to 40 of about 4,280,291 (335)
Frontiers in Immunology, 2018 Adipose tissue is a metabolic organ that plays a central role in controlling systemic energy homeostasis. Compelling evidence indicates that immune system is closely linked to healthy physiologic functions and pathologic dysfunction of adipose tissue. In
Yoon Jeong Park +8 more
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Lipids in Health and Disease, 2020 Obesity exhibits a correlation with metabolic inflammation and endoplasmic reticulum stress, promoting the progression of metabolic disease such as diabetes, hyperlipidemia, hyperuricemia and so on.
Yunjia Li, Ke Yun, Runqing Mu
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LLC tumor cells-derivated factors reduces adipogenesis in co-culture system
Heliyon, 2018 Cancer cachexia (CC) is a multifactorial syndrome with an unknown etiology. The primary symptom is the progressive reduction of the body weight. Recently, down-regulation of adipogenic and lipogenic genes were demonstrated to be early affected during ...
Magno Alves Lopes +4 more
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Stem Cell Research & Therapy, 2021 Background In human subcutaneous adipose tissue, the superficial fascia distinguishes superficial and deep microenvironments showing extensions called retinacula cutis.
Leandra Santos Baptista +7 more
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Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation
Nature Communications, 2017 VLDLR regulates cellular lipoprotein uptake and storage. Here, the authors show that VLDLR, expressed on adipose tissue macrophages, is upregulated in obesity and promotes adipose tissue inflammation by upregulating ceramide production and facilitating ...
Kyung Cheul Shin +10 more
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Frontiers in Cardiovascular Medicine, 2020 Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date several types of adipose tissue have been identified, namely white, brown, and beige, that reside in various specific anatomical locations throughout the body. The
A. Chait, Laura J. den Hartigh
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Nature Communications, 2016 The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic glucose ...
Hagoon Jang +11 more
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Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
Frontiers in Physiology, 2020 Obesity is one of the major health burdens of the 21st century as it contributes to the growing prevalence of its related comorbidities, including insulin resistance and type 2 diabetes.
Federica Zatterale +6 more
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Journal of Cardiovascular Development and Disease, 2023 The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to ...
Joana Ferreira +12 more
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World Journal of Diabetes, 2015 The increasing prevalence of obesity causes a major interest in white adipose tissue biology. Adipose tissue cells are surrounded by extracellular matrix proteins whose composition and remodeling is of crucial importance for cell function. The expansion of adipose tissue in obesity is linked to an inappropriate supply with oxygen and hypoxia ...
Christa, Buechler +2 more
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