Results 31 to 40 of about 4,418,865 (434)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization.
Journal of Clinical Investigation, 2007 Adipose tissue macrophages (ATMs) infiltrate adipose tissue during obesity and contribute to insulin resistance. We hypothesized that macrophages migrating to adipose tissue upon high-fat feeding may differ from those that reside there under normal diet ...
C. Lumeng, Jennifer L Bodzin, A. Saltiel
semanticscholar +1 more source
Frontiers in Cardiovascular Medicine, 2020 Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date several types of adipose tissue have been identified, namely white, brown, and beige, that reside in various specific anatomical locations throughout the body. The
A. Chait, Laura J. den Hartigh
semanticscholar +1 more source
Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? [PDF]
, 2017 Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride
Freeman, Dilys J. +2 more
core +1 more source
Adipose Tissue Inflammation and Metabolic Dysfunction in Obesity.
American Journal of Physiology - Cell Physiology, 2020 Several lines of preclinical and clinical research have confirmed that chronic low-grade inflammation of adipose tissue is mechanistically linked to metabolic disease and organ tissue complications in the overweight and obese organism.
Tatsuo Kawai, M. Autieri, R. Scalia
semanticscholar +1 more source
Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes [PDF]
, 2017 Obesity is an important public health issue worldwide, where it is commonly associated with the development of metabolic disorders, especially insulin resistance (IR).
Agustin Gutierrez, Jaime +11 more
core +2 more sources
Human adipose tissue is a source of multipotent stem cells.
Molecular Biology of the Cell, 2002 Much of the work conducted on adult stem cells has focused on mesenchymal stem cells (MSCs) found within the bone marrow stroma. Adipose tissue, like bone marrow, is derived from the embryonic mesenchyme and contains a stroma that is easily isolated ...
P. Zuk +9 more
semanticscholar +1 more source
Frontiers in Physiology, 2018 Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic regimen of regular exercise and pharmaceutical treatment is often recommended for their clinical management.
Luana G. Leal +4 more
doaj +1 more source
Identification and importance of brown adipose tissue in adult humans.
New England Journal of Medicine, 2009 BACKGROUND Obesity results from an imbalance between energy intake and expenditure. In rodents and newborn humans, brown adipose tissue helps regulate energy expenditure by thermogenesis mediated by the expression of uncoupling protein 1 (UCP1), but ...
A. Cypess +11 more
semanticscholar +1 more source
Omental adipose tissue is a more suitable source of canine Mesenchymal stem cells [PDF]
, 2017 Background: Mesenchymal Stem Cells (MSCs) are a promising therapeutic tool in veterinary medicine. Currently the subcutaneous adipose tissue is the leading source of MSCs in dogs.
Bahamondes, Francisca +4 more
core +2 more sources
The colors of adipose tissue [PDF]
Gaceta Médica de México, 2023 Adipose tissue is an endocrine organ with high metabolic activity. Countless adipose tissue-secreted adipokines and lipokines, as well as peptides and lipids with biological activity have thus far been discovered. Both white and brown and beige adipose tissue are known to contribute to energy homeostasis and metabolic regulation.
María E. Frigolet +1 more
openaire +2 more sources