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Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? [PDF]
, 2017 Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride
Freeman, Dilys J. +2 more
core +1 more source
Identification and importance of brown adipose tissue in adult humans.
New England Journal of Medicine, 2009 BACKGROUND Obesity results from an imbalance between energy intake and expenditure. In rodents and newborn humans, brown adipose tissue helps regulate energy expenditure by thermogenesis mediated by the expression of uncoupling protein 1 (UCP1), but ...
A. Cypess +11 more
semanticscholar +1 more source
Changes in adenosine 5'-monophosphate-activated protein kinase as a mechanism of visceral obesity in Cushing's syndrome [PDF]
, 2008 OBJECTIVE: Features of the metabolic syndrome such as central obesity with insulin resistance and dyslipidemia are typical signs of Cushing's syndrome and common side effects of prolonged glucocorticoid treatment.
Blerina Kola +31 more
core +1 more source
The colors of adipose tissue [PDF]
Gaceta Médica de México, 2023 Adipose tissue is an endocrine organ with high metabolic activity. Countless adipose tissue-secreted adipokines and lipokines, as well as peptides and lipids with biological activity have thus far been discovered. Both white and brown and beige adipose tissue are known to contribute to energy homeostasis and metabolic regulation.
María E. Frigolet +1 more
openaire +2 more sources
Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes [PDF]
, 2017 Obesity is an important public health issue worldwide, where it is commonly associated with the development of metabolic disorders, especially insulin resistance (IR).
Agustin Gutierrez, Jaime +11 more
core +2 more sources
Frontiers in Immunology, 2018 Adipose tissue is a metabolic organ that plays a central role in controlling systemic energy homeostasis. Compelling evidence indicates that immune system is closely linked to healthy physiologic functions and pathologic dysfunction of adipose tissue. In
Yoon Jeong Park +8 more
doaj +1 more source
Lipids in Health and Disease, 2020 Obesity exhibits a correlation with metabolic inflammation and endoplasmic reticulum stress, promoting the progression of metabolic disease such as diabetes, hyperlipidemia, hyperuricemia and so on.
Yunjia Li, Ke Yun, Runqing Mu
doaj +1 more source
Stem Cell Research & Therapy, 2021 Background In human subcutaneous adipose tissue, the superficial fascia distinguishes superficial and deep microenvironments showing extensions called retinacula cutis.
Leandra Santos Baptista +7 more
doaj +1 more source
Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
Frontiers in Physiology, 2020 Obesity is one of the major health burdens of the 21st century as it contributes to the growing prevalence of its related comorbidities, including insulin resistance and type 2 diabetes.
Federica Zatterale +6 more
semanticscholar +1 more source
A pyrexic effect of FGF21 independent of energy expenditure and UCP1
Molecular Metabolism, 2021 Objective: Administration of FGF21 to mice reduces body weight and increases body temperature. The increase in body temperature is generally interpreted as hyperthermia, i.e.
Petr Zouhar +10 more
doaj