Results 31 to 40 of about 4,454,068 (344)

Autophagy in Adipose Tissue [PDF]

open access: yesObesity Facts, 2012
The possible involvement of the evolutionarily conserved process of autophagy (selfeating) in the pathogenesis of human diseases has been increasingly appreciated in recent years. However, at present, many fundamental questions remain to be answered before autophagy can be considered as a therapeutic target: The biological consequences of activating or
Matthias Blüher   +5 more
openaire   +3 more sources

Persistent organic pollutant burden, experimental POP exposure and tissue properties affect metabolic profiles of blubber from grey seal pups [PDF]

open access: yes, 2018
Persistent organic pollutants (POPs) are toxic, ubiquitous, resist breakdown, bioaccumulate in living tissue and biomagnify in food webs. POPs can also alter energy balance in humans and wildlife.
Bennett, Kimberley A.   +5 more
core   +3 more sources

Regulation of tissue crosstalk by skeletal muscle-derived myonectin and other myokines. [PDF]

open access: yes, 2012
The integrated control of animal physiology requires intimate tissue crosstalk, a vital task mediated by circulating humoral factors. As one type of these factors, adipose tissue-derived adipokines have recently garnered attention as important regulators
Seldin, Marcus M, Wong, G William
core   +1 more source

The Importance of Breast Adipose Tissue in Breast Cancer

open access: yesInternational Journal of Molecular Sciences, 2020
Adipose tissue is a complex endocrine organ, with a role in obesity and cancer. Adipose tissue is generally linked to excessive body fat, and it is well known that the female breast is rich in adipose tissue.
Charu Kothari, C. Diorio, F. Durocher
semanticscholar   +1 more source

Changes in adenosine 5'-monophosphate-activated protein kinase as a mechanism of visceral obesity in Cushing's syndrome [PDF]

open access: yes, 2008
OBJECTIVE: Features of the metabolic syndrome such as central obesity with insulin resistance and dyslipidemia are typical signs of Cushing's syndrome and common side effects of prolonged glucocorticoid treatment.
Blerina Kola   +31 more
core   +1 more source

Adipose Tissue Fibrosis: Mechanisms, Models, and Importance

open access: yesInternational Journal of Molecular Sciences, 2020
Increases in adipocyte volume and tissue mass due to obesity can result in inflammation, further dysregulation in adipose tissue function, and eventually adipose tissue fibrosis.
Megan K. DeBari, R. Abbott
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Adipose Tissue and Atherothrombosis [PDF]

open access: yesPathophysiology of Haemostasis and Thrombosis, 2003
Obesity is associated with increased cardiovascular mortality and morbidity mainly through insulin resistance. Dysregulation of protein secretion by adipose tissue is involved in obesity-related diseases. Adipose tissue contributes to create a subinflammatory status which could explain the disturbances in the haemostatic and fibrinolytic systems ...
Marie-Christine Alessi   +3 more
openaire   +3 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Functional Implications of DNA Methylation in Adipose Biology. [PDF]

open access: yes, 2019
The twin epidemics of obesity and type 2 diabetes (T2D) are a serious health, social, and economic issue. The dysregulation of adipose tissue biology is central to the development of these two metabolic disorders, as adipose tissue plays a pivotal role ...
Kang, Sona, Ma, Xiang
core  

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