Results 31 to 40 of about 691,764 (342)
Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? [PDF]
, 2017 Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride
Freeman, Dilys J. +2 more
core +1 more source
Lipids in Health and Disease, 2020 Obesity exhibits a correlation with metabolic inflammation and endoplasmic reticulum stress, promoting the progression of metabolic disease such as diabetes, hyperlipidemia, hyperuricemia and so on.
Yunjia Li, Ke Yun, Runqing Mu
doaj +1 more source
Stem Cell Research & Therapy, 2021 Background In human subcutaneous adipose tissue, the superficial fascia distinguishes superficial and deep microenvironments showing extensions called retinacula cutis.
Leandra Santos Baptista +7 more
doaj +1 more source
Using blubber explants to investigate adipose function in grey seals:glycolytic, lipolytic and gene expression responses to glucose and hydrocortisone [PDF]
, 2017 Adipose tissue is fundamental to energy balance, which underpins fitness and survival. Knowledge of adipose regulation in animals that undergo rapid fat deposition and mobilisation aids understanding of their energetic responses to rapid environmental ...
Bennett, Kimberley A. +4 more
core +3 more sources
Imaging of Adipose Tissue [PDF]
, 2014 Adipose tissue is an endocrine organ that specializes in lipid metabolism and is distributed throughout the body in distinct white adipose tissue (WAT) and brown adipose tissue (BAT) depots. These tissues have opposing roles in lipid metabolism with WAT storing excessive caloric intake in the form of lipid, and BAT burning lipid through nonshivering ...
Ryan, Berry +5 more
openaire +2 more sources
LLC tumor cells-derivated factors reduces adipogenesis in co-culture system
Heliyon, 2018 Cancer cachexia (CC) is a multifactorial syndrome with an unknown etiology. The primary symptom is the progressive reduction of the body weight. Recently, down-regulation of adipogenic and lipogenic genes were demonstrated to be early affected during ...
Magno Alves Lopes +4 more
doaj +1 more source
RPB4 and pathogenesis of diabetes [PDF]
, 2007 Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh +1 more
core +1 more source
Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation
Nature Communications, 2017 VLDLR regulates cellular lipoprotein uptake and storage. Here, the authors show that VLDLR, expressed on adipose tissue macrophages, is upregulated in obesity and promotes adipose tissue inflammation by upregulating ceramide production and facilitating ...
Kyung Cheul Shin +10 more
doaj +1 more source
Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes [PDF]
, 2017 Obesity is an important public health issue worldwide, where it is commonly associated with the development of metabolic disorders, especially insulin resistance (IR).
Agustin Gutierrez, Jaime +11 more
core +2 more sources
Nature Communications, 2016 The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic glucose ...
Hagoon Jang +11 more
doaj +1 more source