Results 51 to 60 of about 4,507,088 (388)
Nature Communications, 2016 The clock protein Cry regulates hepatic glucose metabolism. Here the authors show that SREBP1c, activated by insulin signalling after feeding, directly regulates Cry transcription at specific circadian time points, and that Cry represses hepatic glucose ...
Hagoon Jang +11 more
doaj +1 more source
Adipose Tissue and Atherosclerosis [PDF]
Physiological Research, 2015 High-energy intake which exceeds energy expenditure leads to the accumulation of triglycerides in adipose tissue, predominantly in large-size adipocytes. This metabolic shift, which drives the liver to produce atherogenic dyslipidemia, is well documented.
Rudolf Poledne +2 more
openaire +2 more sources
Journal of Cardiovascular Development and Disease, 2023 The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to ...
Joana Ferreira +12 more
doaj +1 more source
Differential Tissue Response to Growth Hormone in Mice [PDF]
, 2018 Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R. +4 more
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Role of adipose tissue grafting and adipose-derived stem cells in peripheral nerve surgery
Neural Regeneration Research, 2022 The application of autologous fat grafting in reconstructive surgery is commonly used to improve functional form. This review aims to provide an overview of the scientific evidence on the biology of adipose tissue, the role of adipose-derived stem cells,
Tiam M Saffari +4 more
doaj +1 more source
Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]
, 2018 Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M. +3 more
core +3 more sources
Autophagy in Adipose Tissue [PDF]
Obesity Facts, 2012 The possible involvement of the evolutionarily conserved process of autophagy (selfeating) in the pathogenesis of human diseases has been increasingly appreciated in recent years. However, at present, many fundamental questions remain to be answered before autophagy can be considered as a therapeutic target: The biological consequences of activating or
Matthias Blüher +5 more
openaire +3 more sources
RPB4 and pathogenesis of diabetes [PDF]
, 2007 Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh +1 more
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Armaghane Danesh Bimonthly Journal, 2022 Background & aim: Ulcerative colitis is an inflammatory disease of the large intestine that cannot be treated, but its symptoms can be controlled. In traditional medicine, for the basic treatment of colitis, it is necessary to first prevent this abnormal
N Fitras +4 more
doaj
Changes in adenosine 5'-monophosphate-activated protein kinase as a mechanism of visceral obesity in Cushing's syndrome [PDF]
, 2008 OBJECTIVE: Features of the metabolic syndrome such as central obesity with insulin resistance and dyslipidemia are typical signs of Cushing's syndrome and common side effects of prolonged glucocorticoid treatment.
Blerina Kola +31 more
core +1 more source