Results 11 to 20 of about 15,146 (241)

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination

Scientific Reports, 2022
Infection is the most common cause of mortality early in life, yet the broad potential of immunization is not fully realized in this vulnerable population. Most vaccines are administered during infancy and childhood, but in some cases the full benefit of
David J. Dowling, Soumik Barman, Alyson J. Smith, Francesco Borriello, Danielle Chaney, Spencer E. Brightman, Gandolina Melhem, Byron Brook, Manisha Menon, Dheeraj Soni, Simone Schüller, Karthik Siram, Etsuro Nanishi, Hélène G. Bazin, David J. Burkhart, Ofer Levy, Jay T. Evans   +16 more
doaj   +1 more source

Near-infrared laser adjuvant for influenza vaccine. [PDF]

PLoS ONE, 2013
Safe and effective immunologic adjuvants are often essential for vaccines. However, the choice of adjuvant for licensed vaccines is limited, especially for those that are administered intradermally.
Satoshi Kashiwagi, Jianping Yuan, Benjamin Forbes, Mathew L Hibert, Eugene L Q Lee, Laura Whicher, Calum Goudie, Yuan Yang, Tao Chen, Beth Edelblute, Brian Collette, Laurel Edington, James Trussler, Jean Nezivar, Pierre Leblanc, Roderick Bronson, Kosuke Tsukada, Makoto Suematsu, Jeffrey Dover, Timothy Brauns, Jeffrey Gelfand, Mark C Poznansky   +21 more
doaj   +1 more source

SARS-CoV-2 vaccine-triggered autoimmunity: Molecular mimicry and/or bystander activation of the immune system [PDF]

BioImpacts, 2023
Induced autoimmunity or autoinflammatory-like conditions as a rare vaccine-related adverse event have been reported following COVID-19 vaccination.
Azam Safary, Mostafa Akbarzadeh-Khiavi, Jaleh Barar, Yadollah Omidi   +3 more
doaj   +1 more source

Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge

Scientific Reports, 2021
Vaccines based on live attenuated Chlamydia elementary bodies (EBs) can cause disease in vaccinated animals and the comparably safer inactivated whole EBs are only marginally protective.
Zonghui Zuo, Yongjuan Zou, Qiang Li, Yongxia Guo, Tianyuan Zhang, Jie Wu, Cheng He, Francis O. Eko   +7 more
doaj   +1 more source

Studying the Immunogenic Properties of Plague Microbe Capsule Antigen F1 Conjugated with Nanoparticles of Colloid Gold and Silver

Проблемы особо опасных инфекций, 2008
Influence of nanoparticles of colloid gold (CG) and silver (CS) on immunobiological properties of antigens and possibility of their application as adjuvants for antibody formation stimulation were studied.
M. N. Kireev, T. A. Polunina, N. P. Guseva, N. A. Podboronova, Ya. M. Krasnov, T. M. Taranenko   +5 more
doaj   +1 more source

Imiquimod 5% cream in the treatment of superficial and nodular basal cell carcinomas: study of 10 cases Tratamento tópico do carcinoma basocelular superficial e nodular pelo imiquimod creme a 5%: observação de 10 casos

Anais Brasileiros de Dermatologia, 2002
BACKGROUND: Topical treatment with 5% imiquimod cream has been demonstrated to be effective in patients with basal cell carcinoma. OBJECTIVES: In the present study, efficacy and tolerability of this treatment was analyzed in 10 patients with 13 different
Cyro Festa Neto
doaj   +1 more source

Immunosenescence and novel vaccination strategies for the elderly

Frontiers in Immunology, 2013
Vaccination remains the most effective prophylactic intervention for infectious disease in the healthcare professional’s toolkit. However, the efficacy and effectiveness of vaccines decrease with age.
Michael Geoffrey Dorrington, Dawn M.E. Bowdish   +1 more
doaj   +1 more source

PPAR agonists as effective adjuvants for COVID-19 vaccines, by modifying immunogenetics: a review of literature

Journal of Genetic Engineering and Biotechnology, 2021
Background Several coronavirus vaccine have been fast-tracked to halt the pandemic, the usage of immune adjuvants that can boost immunological memory has come up to the surface.
Antoine Fakhry AbdelMassih, Rahma Menshawey, Jumana H. Ismail, Reem J. Husseiny, Yousef M. Husseiny, Shenoda Yacoub, Aya Kamel, Rafeef Hozaien, Elaria Yacoub, Esraa Menshawey, Abanoub Abdelmalek, Ahmed Abouelazaem, Ahmed Elhatw, Ahmed Aboelmaaty, Alaaelrahman Shahib, Amany Mansour, Aya Kamal, Basant Mohamed, Bemen Atif, Beshoy Ghabreal, Catherine Abdelmalak, David Ibrahim, Ebtesam Elsaify, Farah Magdy, Farid G. Hanna, Hadeer Hafez, Hafsa Dahir, Kerlos Merhom, Maram Ahmed, Mariam Bishara, Mina Tawfik, Mina Youssef, Mohamed El Sharnouby, Mourad Hamouda, Musheera Ammar, Nada Ali, Nada Daniel, Nadine El-Husseiny, Noha Abdelraouf, Nuran K. Abdelhameed, Radwa Ahmed, Radwa Othman, Rahma Mohamadein, Rana Allam, Rana Elgendy, Rana Shebl, Saged Elsherbiney, Sarah Fouad, Sara Emel, Sara Owais, Sarah Hetta, Samah El-Saman, Shaimaa Abdelalim, Sherin Galal, Yara Asar, Yara Osman, Yasmeen Khalaf, Youstina Aziz, Yousra Khafagy, Nervana Gamal, Biagio Castaldi   +60 more
doaj   +1 more source

Oral inactivated whole cell vaccine for mucosal immunization: ETVAX case study

Frontiers in Immunology, 2023
Oral immunization is an effective strategy for inducing protective immunity against mucosal enteric pathogens. Although live-attenuated as well as subunit approaches have been explored for vaccination against enteric pathogens, inactivated whole ...
Richard I. Walker, A. Louis Bourgeois
doaj   +1 more source

Role of the immune system and possible mechanisms in COVID-19 vaccine-induced thyroiditis: Case report and literature review

Journal of Clinical and Translational Endocrinology Case Reports, 2022
Introduction: Subacute thyroiditis (SAT) is an inflammatory disease that has different trigger factors. Recent studies show the possible role of COVID-19 vaccine-induced thyroiditis in its initiation.
Vahid Reisi-Vanani, Mahour Farzan, Mahan Farzan, Hosein Ataei-Goujani, Maryam Keihani, Golshan Taghipour-Boroujeni   +5 more
doaj   +1 more source