A novel cellular pathway of antigen presentation and CD4 T cell activation in vivo [PDF]
Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity.
Baz Morelli, Adriana+10 more
core +5 more sources
Establishing the pig as a large animal model for vaccine development against human cancer [PDF]
Immunotherapy has increased overall survival of metastatic cancer patients, and cancer antigens are promising vaccine targets. To fulfill the promise, appropriate tailoring of the vaccine formulations to mount in vivo cytotoxic T cell (CTL) responses ...
Adam+50 more
core +5 more sources
ASIA and BIA-ALCL as adverse reactions to silicone breast implants [PDF]
Adjuvant-induced autoimmune/inflammatory syndrome leads to capsular contracture and fibrosis from the oxidation that takes place in silicone.
Natalia Silva Zahdi+3 more
doaj +1 more source
Adjuvant-induced autoimmune syndrome triggered by silicone breast implants: systematic review [PDF]
Adjuvant-induced autoimmune syndrome (ASIA) and its diagnostic criteria were described by Shoenfeld in 2011, relating symptoms of autoimmunity to adjuvants, such as silicone, present in breast implants.
Caio Munaretto Giacomazzo+5 more
doaj +1 more source
Continuous Treatment with IncobotulinumtoxinA Despite Presence of BoNT/A Neutralizing Antibodies: Immunological Hypothesis and a Case Report. [PDF]
Botulinum Neurotoxin A (BoNT/A) is a bacterial protein that has proven to be a valuable pharmaceutical in therapeutic indications and aesthetic medicine.
Martin MU, Tay CM, Siew TW.
europepmc +2 more sources
Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
Respiratory syncytial virus (RSV) poses a significant burden on public health, causing lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals.
Kay Choong See
doaj +1 more source
Application of built-in adjuvants for epitope-based vaccines [PDF]
Several studies have shown that epitope vaccines exhibit substantial advantages over conventional vaccines. However, epitope vaccines are associated with limited immunity, which can be overcome by conjugating antigenic epitopes with built-in adjuvants (e.
Yao Lei+6 more
doaj +2 more sources
BACKGROUND:. We report the case of a patient with aplastic anemia and pancytopenia on immune-suppressive therapy who developed invasive pulmonary infection with mucormycosis and was treated with immune adjuvant therapy. CASE SUMMARY:. Given the patient’s
Zachary D. Crees, MD+8 more
doaj +1 more source
SARS-CoV-2 vaccine-triggered autoimmunity: Molecular mimicry and/or bystander activation of the immune system [PDF]
Induced autoimmunity or autoinflammatory-like conditions as a rare vaccine-related adverse event have been reported following COVID-19 vaccination.
Azam Safary+3 more
doaj +1 more source
Infection is the most common cause of mortality early in life, yet the broad potential of immunization is not fully realized in this vulnerable population. Most vaccines are administered during infancy and childhood, but in some cases the full benefit of
David J. Dowling+16 more
doaj +1 more source