Results 11 to 20 of about 109,574 (350)
Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells. [PDF]
PLoS ONE, 2015 We previously described that in a rat model of heart transplantation tolerance was dependent on CD8+CD45RClow Tregs that over-expressed fibrinogen-like protein 2 (FGL2)/fibroleukin. Little is known on the immunoregulatory properties of FGL2.
Séverine Bézie +10 more
doaj +1 more source
Adoptive cell transfer using autologous tumor infiltrating lymphocytes in gynecologic malignancies. [PDF]
Gynecol Oncol, 2018 Mayor P, Starbuck K, Zsiros E.
europepmc +3 more sources
Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. [PDF]
PLoS ONE, 2012 Both nature and induced regulatory T (Treg) lymphocytes are potent regulators of autoimmune and allergic disorders. Defects in endogenous Treg cells have been reported in patients with allergic asthma, suggesting that disrupted Treg cell-mediated ...
Wei Xu +14 more
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A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro. [PDF]
PLoS ONE, 2014 Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients.
Tatsuya Moutai +3 more
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Adoptive Transfer of Memory B Cells [PDF]
BIO-PROTOCOL, 2015 The adoptive transfer of antigen-specific B cells into mice that cannot recognize that specific antigen has two main advantages. The first is determining exactly when the B cells were transferred and exposed to antigen. The second is that all B cells that can bind that antigen are the ones that were transferred; no new antigen-specific B cells will ...
Griselda Zuccarino-Catania +1 more
openaire +3 more sources
Frontiers in Immunology, 2023 Efficient intratumoral infiltration of adoptively transferred cells is a significant barrier to effectively treating solid tumors with adoptive cellular transfer (ACT) therapies. Our recent forward genetic, whole-genome screen identified T cell-intrinsic
Vianca V. Vianzon +4 more
doaj +1 more source
High-affinity T cell receptors for adoptive cell transfer. [PDF]
J Clin Invest, 2019 Adoptive cell transfer (ACT) of engineered T cell receptors (TCRs) for cancer immunotherapy has evolved from simple gene transfer of isolated TCRs to various affinity enhancement techniques that overcome limitations imposed by central and peripheral tolerance on TCR affinity. In the current issue of the JCI, Poncette et al.
Isser A, Schneck JP.
europepmc +4 more sources
OncoImmunology, 2012 During the last two decades, several approaches for the activation of the immune system against cancer have been developed. These include rather unselective maneuvers such as the systemic administration of immunostimulatory agents (e.g., interleukin-2) as well as targeted interventions, encompassing highly specific monoclonal antibodies, vaccines and ...
Galluzzi, Lorenzo +8 more
openaire +2 more sources
iScience, 2023 Summary: Adoptive transfer of hepatitis B virus (HBV) immunity may occur following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we investigated the adoptive transfer of HBV immunity in 112 patients without HBV surface antibody ...
Jinhua Ren +17 more
doaj +1 more source
Adoptive Immunotherapy Based on Chain-Centric TCRs in Treatment of Infectious Diseases
iScience, 2020 Summary: Complications after vaccination, lack of vaccines against certain infections, and the emergence of antibiotic-resistant microorganisms point to the need for alternative ways of protection and treatment of infectious diseases. Here, we proposed a
Anastasiia A. Kalinina +8 more
doaj +1 more source