Results 21 to 30 of about 63,665 (250)
Adoptive cell transfer using autologous tumor infiltrating lymphocytes in gynecologic malignancies. [PDF]
Gynecol Oncol, 2018 Mayor P, Starbuck K, Zsiros E.
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iScience, 2023 Summary: Adoptive transfer of hepatitis B virus (HBV) immunity may occur following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we investigated the adoptive transfer of HBV immunity in 112 patients without HBV surface antibody ...
Jinhua Ren +17 more
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Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent. [PDF]
PLoS ONE, 2016 In this study, we compared two lines of transgenic CD8+ T cells specific for the same KdM282-90 epitope of respiratory syncytial virus in the CB6F1 hybrid mouse model. Here we found that these two transgenic lines had similar in vivo abilities to control
Kaitlyn M Morabito +3 more
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Adoptive Immunotherapy Based on Chain-Centric TCRs in Treatment of Infectious Diseases
iScience, 2020 Summary: Complications after vaccination, lack of vaccines against certain infections, and the emergence of antibiotic-resistant microorganisms point to the need for alternative ways of protection and treatment of infectious diseases. Here, we proposed a
Anastasiia A. Kalinina +8 more
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Treatment of lymphoma with adoptively transferred T cells [PDF]
Expert Opinion on Biological Therapy, 2009 Chemotherapy-resistant lymphomas can be cured with allogeneic hematopoietic cell transplantation, demonstrating the susceptibility of these tumors to T cell mediated immune responses. However, high rates of transplant-related morbidity and mortality limit this approach.
Brian G, Till, Oliver W, Press
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iScience, 2020 Summary: The viral antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress hepatitis B virus (HBV) infection. After adoptive transfer, PSC-CTLs can infiltrate into
Mohammad Haque +10 more
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TARGETING TUMOURS BY ADOPTIVE TRANSFER OF IMMUNE CELLS [PDF]
Clinical and Experimental Pharmacology and Physiology, 2006 1. Surgery, radiotherapy and chemotherapy are the most widely used and well-established modalities for treating malignant diseases. Surgery is used to excise solid tumours and radiotherapy/chemotherapy are used for the treatment of liquid tumours and for solid tumours where there is a risk of micrometastases.
P A, Macary, C T, Too, X, Dai
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ADOPTIVE CELL THERAPY: CURRENT ADVANCES
Южно-Российский онкологический журнал, 2020 The immune system plays an important role in the development and treatment of many cancer types. This fact determined the emergence of numerous immunotherapeutic approaches, including that of adoptive cell therapy (ACT).
T. V. Shamova +3 more
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Journal of Hematology & Oncology, 2019 Background Allogeneic hematopoietic stem cell transplantation (HSCT) can expose patients to a transient but marked immunosuppression, during which viral infections are an important cause of morbidity and mortality.
Theresa Kaeuferle +4 more
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Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes
Journal for ImmunoTherapy of Cancer, 2020 Background Genome editing offers unique perspectives for optimizing the functional properties of T cells for adoptive cell transfer purposes. So far, PDCD1 editing has been successfully tested mainly in chimeric antigen receptor T (CAR-T) cells and human
Nathalie Labarrière +17 more
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