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Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytes

open access: goldOncoImmunology, 2021
The optimization of adoptive transfer approaches of anti-tumor T cells requires both the functional improvement of the injected T cells and the modulation of the tumor microenvironment, favoring the recruitment of these T cells and their activation.
L Marotte   +13 more
doaj   +2 more sources

Adoptive immune transfer from donors offers Anti-HBV protection to HBsAb-negative patients after Allo-HSCT

open access: greeniScience, 2023
Summary: Adoptive transfer of hepatitis B virus (HBV) immunity may occur following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we investigated the adoptive transfer of HBV immunity in 112 patients without HBV surface antibody ...
Jinhua Ren   +17 more
doaj   +3 more sources

Adoptive Cellular Transfer Immunotherapies for Cancer

open access: yesCancer Treatment and Research Communications, 2022
Patients with cancer require efficient treatment approaches as the mortality rate due to their disease is high. Conventional therapies, like chemotherapy and radiation, have severe side effects.
Panagiotis Parsonidis   +1 more
doaj   +3 more sources

Adoptive Transfer of Memory B Cells [PDF]

open access: yesBio-Protocol, 2015
The adoptive transfer of antigen-specific B cells into mice that cannot recognize that specific antigen has two main advantages. The first is determining exactly when the B cells were transferred and exposed to antigen.
Griselda Zuccarino-Catania   +1 more
doaj   +3 more sources

Is It Feasible to Use CMV-Specific T-Cell Adoptive Transfer as Treatment Against Infection in SOT Recipients? [PDF]

open access: yesFrontiers in Immunology, 2021
During the last decade, many studies have demonstrated the role of CMV specific T-cell immune response on controlling CMV replication and dissemination. In fact, it is well established that transplanted patients lacking CMV-specific T-cell immunity have ...
Estéfani García-Ríos   +3 more
doaj   +2 more sources

Adoptive Transfer of Isolated Bone Marrow Neutrophils [PDF]

open access: yesBio-Protocol, 2012
Adoptive transfer experiments of specific cell populations are widely used methods to assess the role of the injected population on an ongoing process.
Jimena Boari, Eva Rodríguez
doaj   +4 more sources

MAIT Cell Adoptive Transfer v1 [PDF]

open access: gold, 2020
This is part 3.2 of the "Study of MAIT Cell Activation in Viral Infections In Vivo" collection of protocols. Collection Abstract: MAIT cells are abundant, highly evolutionarily conserved innate-like lymphocytes expressing a semi-invariant T cell receptor (TCR), which recognizes microbially derived small intermediate molecules from the riboflavin ...
Timothy S C Hinks   +7 more
openaire   +2 more sources

Adoptive T-Cell Transfer to Treat Lymphangioleiomyomatosis

open access: greenAmerican Journal of Respiratory Cell and Molecular Biology, 2020
Patients with lymphangioleiomyomatosis (LAM) develop pulmonary cysts associated with neoplastic, smooth muscle-like cells that feature neuroendocrine cell markers. The disease preferentially affects premenopausal women. Existing therapeutics do not cure LAM.
Fei Han   +10 more
openaire   +5 more sources

Adoptive Transfer of Lung Antigen Presenting Cells

open access: yesBio-Protocol, 2017
Our protocol describes adoptive transfer of antigen presenting cells (APCs) isolated from the lungs by enzymatic digestion and magnetic enrichment. This protocol can be used to study APC functions and trafficking.
Xiaofeng Zhou, Bethany Moore
doaj   +4 more sources

Adoptive Transfer of Myeloid-Derived Suppressor Cells and T Cells in a Prostate Cancer Model [PDF]

open access: yesBio-Protocol, 2015
The adoptive transfer of immune cells for cancer, chronic infection, and autoimmunity is an emerging field that has shown promise in recent trials. The transgenic adenocarcinoma mouse prostate (TRAMP) is a classical mouse model of prostate cancer (PCa ...
Libo Yan, Yan Xu
doaj   +3 more sources

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