Results 91 to 100 of about 132,161 (355)

NIH3T3 Directs Memory-Fated CTL Programming and Represses High Expression of PD-1 on Antitumor CTLs

Frontiers in Immunology, 2019
Memory CD8+ T cells have long been considered a promising population for adoptive cell therapy (ACT) due to their long-term persistence and robust re-stimulatory response. NIH3T3 is an immortalized mouse embryonic fibroblast cell line.
Yingyu Qin, Yuna Lee, Jaeho Seo, Taehyun Kim, Jung Hoon Shin, Se-Ho Park   +5 more
doaj   +1 more source

CTLA-4: a negative regulator of autoimmune disease. [PDF]

, 1996
CTLA-4, a CD28 homologue expressed on activated T cells, binds with high affinity to the CD28 ligands, B7-1 (CD80) and B7-2 (CD86). This study was designed to examine the role of CTLA-4 in regulating autoimmune disease.
Bluestone, JA, Karandikar, NJ, Miller, SD, Vanderlugt, CL, Walunas, TL   +4 more
core  

Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system. [PDF]

, 2006
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection.
A. Meyer, A.A. Dandekar, A.D. Luster, B. Mehrad, B. Parra, B. Parra, B.D. Pearce, B.P. Chen, B.T. Fife, C. Gerard, C. Ramakrishna, C. Ramakrishna, C.A. Biron, C.E. Patterson, C.J. Raport, C.M. Hogaboam, D. Franciotta, D. Galimberti, D. Whiting, D.D. Taub, D.J. Mahad, D.M. Muller, D.N. Cook, D.P. Widney, E. Lazzeri, E.J. McMahon, F.R. Fischer, F.S. Cheever, G. Penna, G. Penna, G.B. Huffnagle, G.C. Hildebrandt, G.F. Wu, H. Bartosik-Psujek, H.G. Fischer, H.G. Fischer, I. Banisor, I. Clark-Lewis, I. Salomon, I. Tsunoda, I.E. Flesch, J. Gosling, J.B. Domachowske, J.C. Houck, J.F. Bazan, J.H. Dufour, J.H. Xie, J.J. Phillips, J.M. Farber, J.S. Haring, J.S. Haring, J.S. Williamson, J.S. Williamson, K. Holmes, K. McIntosh, K.E. Balashov, K.S. Held, K.S. Warmington, K.V. Holmes, L. Boring, L. Boring, L. Cartier, L. Gu, L. Gu, L. Pewe, L. Pewe, M. Baggiolini, M. Greter, M. Matsui, M.A. Olszewski, M.J. Buchmeier, M.J. Trifilo, M.J. Trifilo, M.J. Trifilo, M.M. Lai, M.T. Lin, M.T. Lin, M.T. Liu, M.T. Liu, M.T. Liu, N. Sato, N.J. Megjugorac, N.W. Marten, R. Gade-Andavolu, R. Watanabe, R.F. Castro, R.S. Klein, S. Narumi, S. Qin, S. Xue, S.A. Stohlman, S.A. Stohlman, S.D. Miller, S.M. Stamatovic, S.R. Perlman, T.E. Lane, T.E. Lane, T.E. Lane, T.L. Sorensen, T.L. Sorensen, T.S. Kim, T.S. Kim, W.G. Glass, W.G. Glass, W.G. Glass, W.G. Glass, W.J. Karpus, Y. Zhang, Y. Zhou   +108 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Prospectives of T-cells genetic programming in adoptive immunotherapy of malignancies

Сеченовский вестник, 2016
The article reviews the literature on adoptive T-cell therapy of malignancies. Adoptive T-cell transfer allows treatment of metastatic disease on the late stages of certain tumors.
O. L. Morozova, V. V. Yakovlev, N. A. Sushentsev   +2 more
doaj  

MECHANISMS OF IMMUNOSUPPRESSIVE ACTION OF LICORICE ROOT FLAVONOIDS IN CONTACT SENSITIVITY IN MICE: INHIBITION OF T LYMPHOCYTE EFFECTOR FUNCTION MEDIATED BY NON- EFFECTOR CELLS

Медицинская иммунология, 2014
Contact sensitivity is a classical T cell-mediated, clinically important phenomenon elicited by small molecular weight molecules (haptens) that bind to host proteins to form a complete antigen.
S. I. Pavlova, D. Z. Albegova, A. A. Kyagova, I. G. Kozlov   +3 more
doaj   +1 more source

Sometimes it is Better Not to be Unique: The U.S. Department of State View on Intercountry Adoption and Child Trafficking and Why it Should Change [PDF]

, 2014
This event was not ...
Turner, Chad
core   +1 more source

Myocardial aging as a T-cell–mediated phenomenon [PDF]

, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco, Beyersdorf, Niklas, Burkard, Matthias, Frantz, Stefan, Friedrich, Mike, Heinze, Katrin G., Hofmann, Ulrich, Jocelyne, Demengeot, Kerkau, Thomas, Nunes-Silva, Vânia, Peters, Laura, Pinnecker, Jürgen, Ramos, Gustavo Campos, Schuh, Kai, van den Berg, Anne, Weirather, Johannes   +15 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The adoptive transfer of BCG-induced T lymphocytes contributes to hippocampal cell proliferation and tempers anxiety-like behavior in immune deficient mice.

PLoS ONE, 2020
We previously have reported that neonatal Bacillus Calmette-Guerin (BCG) vaccination improves neurogenesis and behavior in early life through affecting the neuroimmune milieu in the brain, but it is uncertain whether activation phenotypes and functional ...
Dan Song, Fangfang Qi, ShuaiShuai Liu, Zhongsheng Tang, Jinhai Duan, Zhibin Yao   +5 more
doaj   +1 more source