Results 11 to 20 of about 3,239,660 (397)

Adoptive Transfer of Lung Antigen Presenting Cells

Bio-Protocol, 2017
Our protocol describes adoptive transfer of antigen presenting cells (APCs) isolated from the lungs by enzymatic digestion and magnetic enrichment. This protocol can be used to study APC functions and trafficking.
Xiaofeng Zhou, Bethany Moore
doaj   +5 more sources

Adoptive Transfer of Basophils Enriched from Mouse Spleen [PDF]

Bio-Protocol, 2019
CD49b is a member of the integrin family, expressed on basophils, natural killer (NK) cells and a subset CD4+ T cells in the spleen. This protocol describes the adoptive transfer of basophil-enriched CD49b+ cells obtained from mouse spleens by magnetic ...
Adrian Piliponsky, Stephen Galli
doaj   +2 more sources

Anti-tumor efficacy of a combination therapy with PD-L1 targeted alpha therapy and adoptive cell transfer of PD-1 deficient melanoma-specific human T-lymphocytes

OncoImmunology, 2021
The optimization of adoptive transfer approaches of anti-tumor T cells requires both the functional improvement of the injected T cells and the modulation of the tumor microenvironment, favoring the recruitment of these T cells and their activation.
L Marotte, M Capitao, C Deleine, T Beauvais, G Cadiou, J. Perrin, M Chérel, E Scotet, Y Guilloux, F Bruchertseifer, A Morgenstern, A Jarry, J. Gaschet, N Labarriere   +13 more
doaj   +1 more source

Allogeneic lymphocytes persist and traffic in feral MHC-matched mauritian cynomolgus macaques. [PDF]

PLoS ONE, 2008
Thus far, live attenuated SIV has been the most successful method for vaccinating macaques against pathogenic SIV challenge; however, it is not clear what mechanisms are responsible for this protection.
Justin M Greene, Benjamin J Burwitz, Alex J Blasky, Teresa L Mattila, Jung Joo Hong, Eva G Rakasz, Roger W Wiseman, Kim J Hasenkrug, Pamela J Skinner, Shelby L O'Connor, David H O'Connor   +10 more
doaj   +1 more source

A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro. [PDF]

PLoS ONE, 2014
Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients.
Tatsuya Moutai, Hideyuki Yamana, Takuya Nojima, Daisuke Kitamura   +3 more
doaj   +1 more source

Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells. [PDF]

PLoS ONE, 2015
We previously described that in a rat model of heart transplantation tolerance was dependent on CD8+CD45RClow Tregs that over-expressed fibrinogen-like protein 2 (FGL2)/fibroleukin. Little is known on the immunoregulatory properties of FGL2.
Séverine Bézie, Elodie Picarda, Laurent Tesson, Karine Renaudin, Justine Durand, Séverine Ménoret, Emmanuel Mérieau, Elise Chiffoleau, Carole Guillonneau, Lise Caron, Ignacio Anegon   +10 more
doaj   +1 more source

Adoptive Cell Transfer Therapy [PDF]

Seminars in Oncology, 2007
Adoptive cell transfer therapy has developed into a potent and effective treatment for patients with metastatic melanoma. Current application of this therapy relies on the ex vivo generation of highly active, highly avid tumor-reactive lymphocyte cultures from endogenous tumor infiltrating lymphocytes or on the genetic engineering of cells using ...
Steven A. Rosenberg, Mark E. Dudley
openaire   +2 more sources

The Endogenous Th17 Response in NO2-Promoted Allergic Airway Disease Is Dispensable for Airway Hyperresponsiveness and Distinct from Th17 Adoptive Transfer [PDF]

, 2013
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
A Abe, A Duguet, A Hoshino, A Vazquez-Tello, A Vazquez-Tello, AG Besnard, AG Besnard, AI Caceres, AJ Coyle, AR Brasier, AR Sousa, AS Saffar, AT Hastie, B Korkmaz, Benjamin T. Suratt, BJ Canning, C Sutton, C Taube, D Stejskal, Daniel J. Weiss, DB Corry, DC Newcomb, DC Newcomb, DC Newcomb, DH Broide, E Goleva, F Kirstein, GJ Zijlstra, H Fujie, H Koga, H Wakashin, Hong Wei Chu, I Tillie-Leblond, J Agbetile, J Chang, J Seok, J Sunyer, J Zhao, JB Cowland, Jennifer L. Ather, JH Bates, JH Lee, JL Ather, JL Ather, John F. Alcorn, JR Karlsen, JV Fahy, K Raemdonck, K Yang, L McKinley, LA Cooney, Laura Hoyt, Lennart K. A. Lundblad, LJ Akinbami, LK Lundblad, LK Lundblad, LK Lundblad, LL Reber, M Bevelander, M Kawaguchi, M Kudo, M Leppkes, M Suzukawa, MA Willart, Matthew E. Poynter, ME Poynter, ME Poynter, ME Poynter, MH Brutsche, MH Shaw, MW Kinyanjui, N Schmitz, PA Wark, PL Delamater, PS Foster, PW Hellings, Q Wang, R He, RA Martin, Rebecca A. Martin, Rebecca Daggett, RH Wilson, S Ano, S Dragon, S Ferretti, S Haak, S Lajoie, S Molet, S Schnyder-Candrian, S Suzuki, S Wenzel, SJ Ballantyne, SM Hu, SP Chapoval, SR Hodgkins, T Li, VJ Johnson, W Al-Ramli, WP Arend, WW Lee, X Yao, XY Chi, Y Chung, Y Liu, Y Takenoue, Y Zhao, YH Wang   +106 more
core   +7 more sources

Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. [PDF]

PLoS ONE, 2012
Both nature and induced regulatory T (Treg) lymphocytes are potent regulators of autoimmune and allergic disorders. Defects in endogenous Treg cells have been reported in patients with allergic asthma, suggesting that disrupted Treg cell-mediated ...
Wei Xu, Qin Lan, Maogen Chen, Hui Chen, Ning Zhu, Xiaohui Zhou, Julie Wang, Huimin Fan, Chun-Song Yan, Jiu-Long Kuang, David Warburton, Dieudonnée Togbe, Bernhard Ryffel, Song-Guo Zheng, Wei Shi   +14 more
doaj   +1 more source

VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer

Cell Communication and Signaling, 2023
Androgen deprivation therapy (ADT) is a standard therapy for prostate cancer (PCa). Though disseminated disease is initially sensitive to ADT, an important fraction of the patients progresses to castration-resistant prostate cancer (CRPC).
Rydell Alvarez-Arzola, Nicoló Bancaro, Ping Lai, Giuseppe Attanasio, Laura Pellegrini, Martina Troiani, Manuel Colucci, Simone Mosole, Emiliano Pasquini, Andrea Alimonti, Circe Mesa   +10 more
doaj   +1 more source